Endocrine Abstracts

Background: Achievement of treatment targets in children and young people (CYP) with diabetes represents an important intermediary step between delivery of care and ‘hard’ outcomes such as complications. Funnel plots have been proposed as a useful tool for visualising variation in performance indicators across centers and distinguishing between common-cause (centers lying within the control limits) and special-cause variation (centers lying outside the control limits...

Aims: The incidence of childhood/adolescent gender identity disorder (GID) is unknown. GID is an important condition where gender identity differs from biological sex. It is associated with significant distress, particularly with puberty, with much controversy internationally over the optimal timing of hormonal treatment. We examine the incidence and clinical presentation in UK/Irish children and adolescents.Methods: Study population: UK/Irish children/a...

Introduction: The impact of ethnicity and socioeconomic status (SES) on glycaemic control in children with type 1 diabetes (T1D) is poorly understood in England and Wales.Methods: We studied 18 478 children and young people with T1D aged <19 years attending diabetes clinics in England and Wales and included in the 2012–2013 National Paediatric Diabetes Audit (NPDA). Self-identified ethnicity was categorized as white, Asian, black, mixed, other a...

Background: Chromosome analysis is always indicated in disorders of sex development (DSD), but the need for karyotyping in gender dysphoria (GD) is less clear.Aims and objectives: We therefore aimed to review the place of routine chromosome analysis in the management of GD in children and adolescents.Patients and methods: Five hundred and twenty children and adolescents with GD have been referred at the time of reporting to the two...

Objectives: To identify patient and clinical factors associated with emergency hospital admission with diabetic ketoacidosis (DKA) in children and young people with type 1 diabetes attending specialist NHS outpatient clinics in England and Wales.Design: Cross-sectional observational analysis of linked data from the National Paediatric Diabetes Audits (NPDAs) in England and Wales, and Hospital Episode Statistics and Patient Episode Database for Wales. We ...

Introduction: Most adolescents with GID have no overt functional or phenotypic abnormalities to explain their presentation. Currently all female to male (FtM) persons undergo detailed evaluation of adrenal function. This study aimed to determine whether subtle abnormalities of adrenal were present and what the appropriate investigation schedule should be.Methods: Over the past 4 years, 55 biological females aged mean age 16.54 years (13.46–18.37) we...

Introduction: Delivering an equitable service is one component defining a quality service. Various factors impact on diabetes control including health beliefs and socioeconomic pressures. To determine the role played by ethnicity and/or deprivation we audited access to insulin treatment regimens and overall diabetes control in our clinic population of children and young people with type 1 diabetes mellitus (CYPT1DM).Methods: Three hundred and twenty-five...