Searchable abstracts of presentations at key conferences in endocrinology

ea0014p478 | (1) | ECE2007

Primary hyperparathyroidism during pregnancy – case report

Mogos Voichita , Mogos Simona , Onofriescu Mircea , Cotea Elena , Tarcoveanu Eugen , Florea Niculina , Zbranca Eusebie

Until 2002 less than 200 cases of primary hyperparathyroidism identified during pregnancy were reported. We present a case of primary hyperparathyroidism discovered during pregnancy in a 28-year-old woman. The disease was suspected due to a hypercalcemia discovered during a routine blood assessment during pregnancy (calcium=11 mg/dl, phosphorus=2.4 mg/dl). The patient was investigated in the Clinic of Endocrinology and the diagnosis of primary hyperparathyroidism was made on b...

ea0037ep244 | Calcium and Vitamin D metabolism | ECE2015

Quick PTH improves the cure rate of minimally invasive surgery in patients with primary hyperparathyroidism and preoperative localized parathyroid adenoma

Velicescu Cristian , Gatu Alina , Danila Radu , Grigorovici Alexandru , Mogos Voichita

Introduction: Intraoperative quick PTH (iqPTH) monitoring is important in the treatment of primary hyperparathyroidism (pHPTH), allowing, together with preoperative localisation, the switch from routine bilateral neck exploration to limited gland excision.Aims: We checked the advantage of iqPTH for improving the cure rate of patients operated for pHPTH by using minimally invasive surgery (MIS).Materials and methods: Retrospective s...

ea0037ep708 | Pituitary: basic and neuroendocrinology | ECE2015

The role of adipocytokinic markers in the prognosis of survival and sepsis at critical postsurgical patients

Florescu Alexandru , Ristescu Irina , Grigoras Ioana , Mogos Voichita , Branisteanu Dumitru

The secretion of adipocytokines is influenced by fat mass, but also by various situations related to acute stress (food deprivation, or critical state related to inflamatory or infectious syndromes). Adipocytokinic secretory profile could be therefore used for the diagnosis of the type of critical state, as well for the evolution and survival prognosis of patients. The modifications of adipocytokinic markers during the first hours after surgical intervention are insufficiently...

ea0037ep1285 | Clinical Cases–Thyroid/Other | ECE2015

Hashimoto's thyroiditis with subclinical hypothyroidism, but severe growth delay in a prepubertal boy

Ghita Emilia , Gatu Alina Andreea , Mogos Voichita , Branisteanu Dumitru

Hashimoto’s thyroiditis is an autoimmnune condition most common in females but can be also found in children with a prevalence of 1.2%. When is associated with hypothyroidism, the growth delay is an important, but late symptom. We present the case of a 12-year-old boy presenting with small height for age (123 cm, <−3 S.D.), important weight gain and fatigue. He was the only child from parents of average height and had normal weight at birth (3300 ...

ea0035p795 | Paediatric endocrinology | ECE2014

A case of velocardiofacial syndrome with short stature associated with partial GH deficiency

Planton Emilia , Rusu Cristina , Mogos Voichita , Branisteanu Dumitru

Introduction: Velocardiofacial syndrome (VCFS) also known as DiGeorge or chonotruncal anomaly face syndrome, is a rare genetic disease caused by a microdeletion in the long arm of chromosome 22, having a prevalence of approximately 1:7000 to 1:4000. VCFS has a wide spectrum of more than 200 physical manifestations including: cleft palate, heart and facial abnormalities, eye pathology, problems with feeding, including nasal regurgitation, middle-ear infections (otitis media), l...

ea0032p634 | Growth hormome IGF axis – basic | ECE2013

GH therapy: never say never; clinical case

Ghita Irina , Profiri Corina , Constantinescu Georgiana , Novac Roxana , Mogos Voichita

We present the case of a patient diagnosed with panhypopituitarism at an adult age. The tenth child of a poor family, PA consulted the endocrinologist accompanied by his 65 year old mother. PA was 20 years old at the first consultation. He was, however, entrapped in the body of a 12 year old child, being only 139 cm tall and having no signs of puberty onset. He was slightly eunuchoid, with long limbs, due to delayed puberty, with micropenis and lack of androgen dependent hair,...

ea0014oc2.6 | Bone &amp; calcium metabolism | ECE2007

Sunlight exposure and vitamin D supplementation at the institutionalized elderly – effects on calcium and bone metabolism

Bottermann Peter , Branisteanu Dumitru , Mogos Voichita , Zbranca Eusebie

We investigated calcium and bone metabolism in a group of 123 institutionalized volunteers between 60 and 98 years old, 73 females and 50 males. 25OH-D3 was measured by an indoor RIA technique. 1.25(OH)2D3 was measured by HPLC, serum calcium by photocolorimetry, bone alkaline phosphatase by immunoenzymatic technique, whereas serum PTH and urinary deoxypyridinoline (DPD) were measured by IRMA. Almost all volunteers (92.6%) had low 25OH-D3</...

ea0014p301 | (1) | ECE2007

The influence of smoking upon the incidence of Graves’ disease and severity of Graves’ ophthalmopathy

Zbranca Eusebie , Branisteanu Dumitru , Scurtu Bogdanel , Mogos Voichita

In order to investigate the relationship between Graves’ disease, its associated ophthalmopathy and smoking, we followed retrospectively a group of 270 patients with Graves’ disease (233 females and 37 males). Smoking incidence within this group was compared to that found in a control, thyroid disease-free group of 120 patients. The incidence of smokers was significantly higher in the group with Graves’ disease (145 out of 270, 54%) when compared to the control ...

ea0014p355 | (1) | ECE2007

The relevance of thyroid echography in diagnostic of subclinical autoimmune thyroiditis during pregnancy and postpartum

Carmne Gorduza , Voichita Mogos , Vlad Gorduza Eusebiu , Eusebie Zbranca

Thyroid diseases are more frequent in women. We made a longitudinal study at 112 healthy pregnant women from Iasi county, Romania. The aim of study was to determine incidence and evolution of autoimmune thyroiditis in pregnancy and postpartum. The proceedings of study imposed to verify clinical aspect of thyroid, the volume of thyroid measured echographic, echostructure of thyroid, function of thyroid (TSH, FT4) and autoimmune modification of thyroid (anti-thyroid peroxidase a...

ea0014p393 | (1) | ECE2007

The predictive role of body mass and composition upon bone mineral content: differences between premenopausal and postmenopausal women

Branisteanu Dumitru , Piciorea Anca , Zbranca Eusebie , Mogos Voichita

Gravitational stress influences bone mass. Adipose tissue represents a supplementary source of estrogens at postmenopausal women, via aromatization of androgens. We evaluated the importance of weight and fat tissue on bone mass at premenopausal or postmenopausal women in a cross-sectional study upon a group of 138 women between 25 and 77 ys old and with a BMI between 17.1 and 44.3 kg/m2. Fifty six women were menstruating, 15 were perimenopausal and 68 were po...