Searchable abstracts of presentations at key conferences in endocrinology

ea0015p15 | Bone | SFEBES2008

Vitamin D status in pregnancy in four ethnic groups

Sethi Mieran , Yu Christina , Newton Lynne , Teoh TG , Robinson Stephen

Background: Vitamin D deficiency in pregnancy is a growing public concern amongst ethnic minority groups in the UK. This is related to both skin colour and clothing.Aim: To investigate vitamin D status in four ethnic groups in an inner city obstetric practice. This was part of an ongoing study of vitamin D deficiency and supplementation in pregnancy.Subjects: Women from St Mary’s Hospital, London were recruited at 28 weeks ges...

ea0094p296 | Thyroid | SFEBES2023

A case of intravenous immunoglobulin induced thyroiditis in pregnancy

Campbell Michael , Agha-Jaffar Rochan , Saad Muhammad , Yu Christina , Robinson Stephen

Intravenous Immunoglobin (IVIG) therapy is used in recurrent miscarriage, despite its efficacy being limited to specific sub-groups such as those with underlying immune conditions. The indications, efficacy and side effect profile of IVIG when used in pregnant women are not established. We present the case of a 41-year-old pregnant woman with one previous miscarriage, who had received IVIG as part of her fertility treatment and subsequently developed profound symptoms and bioc...

ea0090ep329 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

A case series of monogenic diabetes in pregnancy

Nyunt Sandhi , Agha-Jaffar Rochan , Hardy Maud , Racaru Simona , Cunsolo Roberto , Yu Christina , Terry Jayne , Misra Shivani , Robinson Stephen

Monogenic diabetes is estimated to account for 1-2% of all diabetes cases diagnosed before the age of 45. It is caused by mutations in genes encoding for beta cell development, function and regulation. We present three cases of monogenic diabetes in pregnancy.Case 1: Age 30, Para 3, White ethnicity. This individual was screened for a GCK mutation at 18 weeks gestation (third pregnancy) on the basis of family history. She required metformin and insulin to...

ea0094p175 | Adrenal and Cardiovascular | SFEBES2023

Laparoscopic adrenalectomy for phaeochromocytoma in the context of acute coronary syndrome

Soruna Omolayo , Plowman Christina , Yu Thinn , Pittaway James , Goodchild Emily , Wragg Andrew , Fitchat Tracey , Parvanta Laila , Akker Scott

A 54-year-old man presented to the heart attack centre with cardiac chest pain, vomiting and collapse. Biochemistry (troponin incremented from 117 to 315ng/l) and electrocardiogram confirmed a diagnosis of non-ST elevation myocardial infarction (NSTEMI). Past medical history included type 2 diabetes mellitus and hypertension (diagnosed 8 years previously), hypercholesterolaemia and a 20 pack year smoking history. Secondary prevention for MI was commenced and coronary angiograp...

ea0086p326 | Metabolism, Obesity and Diabetes | SFEBES2022

Examining the relationship between gestational diabetes, maternal pre-pregnancy body mass index (BMI) and large for gestation age neonates by ethnicity

Chia Eng Pei , Veidi Chiara , Mullins Edward , Terry Jayne , Jones Bryony , Dornhorst Anne , Uduku Chukwuma , Sykes Lynne , Yu Christina , Robinson Stephen , Agha-Jaffar Rochan

Objective: To determine if the impact of pre-pregnancy body mass index (BMI), fasting glucose levels and post load glucose levels on large for gestational age neonates varies with ethnicity.Data sources: Electronic health records of all eligible pregnant women in an inner city service. Study designRetrospective analysis of pregnant women at risk of developing gestational diabetes mellitus (2016-2019) of. Population or sampleEligible pregnant women. Synth...

ea0073aep86 | Calcium and Bone | ECE2021

A rare case of hypercalcemia in pregnancy- a diagnostic conundrum

Ladha Tasneem , Moriarty Maura , Khan Shaila , Tan Min Yi , Vakilgilani Tannaz , Bravis Vassiliki , Sykes Lynne , Yu Christina , Comninos Alexander , Cox Jeremy , Robinson Stephen , Agha-Jaffar Rochan

Hypercalcaemia in pregnancy is a rare but important finding, given the associated potential risks to mother and baby. These include hypertension, pancreatitis, nephrolithiasis and renal failure in the mother and intrauterine growth restriction, neonatal hypoparathyroidism/hypocalcaemia and stillbirth in the baby (1). We present the case of a 26-year-old female with a background of PTH-independent hypercalcaemia of unknown aetiology. This was initially detected at age 6 months ...