Endocrine Abstracts

Introduction: Primary hyperparatyhyroidism (PHPT) is usually caused by single or multiple adenomas and cancer is rare accounting for <1% of all presentations. The presence of certain cytological and architectural features such as adherence to adjacent organs, a solid growth pattern, broad bands of fibrosis, cytological atypia, and an irregular growth contour do not indicate malignancy but are recognised as atypical features encountered more commonly in malignant than benig...

Introduction: Diabetes mellitus (DM) is an endocrine disease characterised by metabolic abnormalities and long-term complications. Achilles tendon (AT) play an important role in foot biomechanics. We aimed to investigate the effect of DM on the AT, which may contribute to the long-term complications in the foot–ankle complex.Materials and methods: 78 diabetic patients with (35 cases) or without (43 cases) diabetic foot ulcers were recruited from End...

Introduction: Increasing evidence is available for the role of prolactin in the development of various cancers. The purpose of this study is to evaluate the frequency of thyroid cancer in patients with prolactinoma followed up at a single site.Materials and methods: Medical records of 182 patients, diagnosed with prolactinoma, were reviewed retrospectively. Out of these patients, 114 patients (103 female patients, 11 male patients, mean age 35±10.4)...

Introduction: Endocrinological and metabolic changes can occur in critically ill patients, which may affect the prognosis and outcome. The hypothalamic–anterior–pituitary axis (HPA) plays a crucial role in the endocrine regulation of metabolic and immunological homeostasis. In this prospective study, we evaluated the pituitary–adrenal–gonadal–thyroid axis in the adult Intensive Care Unit (ICU) patients,their outcome, the association between these hormo...

Introduction: Neoplasms of the thyroid gland are classified according to the cell that it originates and commonly they originate from follicular or parafollicular C cells. The most common differentiated thyroid cancers (DTC) are papillary and follicular carcinomas. Coexistence of two different histological types of primary follicular thyroid neoplasm is a rare condition. There are previous reports of concomitant medullary and papillary thyroid cancers. However, there is scarce...

Introduction: It is unclear whether ultrasonographic (US) findings and fine-needle aspiration biopsy (FNAB) results of nodules accompanied with Hashimoto’s thyroiditis (HT) are affected by the presence of thyroiditis or not. In this study, we compared US features and cytological results of nodules in patients with and without HT.Methods: Patients who underwent FNAB in our clinic were evaluated prospectively. Nodules in patients with and without HT w...

Visfatin/pre-B-cell enhancement factor is an adipocytokine, which is found in the visceral fat tissue and enhances the growth of precursor of B cells through showing synergy with IL7 and stem cell factors. Other cytokines released from the adipose tissue are TNFα and IL6, which has been shown to be related with pathogenesis of insulin resistance, diabetes, dyslipidaemia, inflammation, and atherosclerosis. Our aim was to determine the relationship of plasma visfatin/pre-B-...

Aim: Exophytic nodule refers to a nodule that sticks out of the normal thyroid boundary/outline. Other definition is a nodule with an acute angle between the lesion and adjacent thyroid capsule. In the literature, one study reported that thyroid nodules with exophytic configuration showed a high malignancy rate. We aimed to compare ultrasonographical features and cytopathologic results of exophytic and non-exophytic thyroid nodules.Material and method: T...

Introduction: Ocular changes and ocular symptoms may be encountered in patients with hypothyroidism and hyperthyroidism. However, the data concerning the effects of thyroid disorders on intraocular pressure (IOP), central corneal thickness (CCT), and retinal thickness (RT) are very rare. Here, we aimed to evaluate the alterations in IOP, CCT, and RT in patients with euthyroid autoimmune thyroiditis (AIT).Methods: Twenty-five subjects with euthyroid AIT w...

Introduction: Diabetes insipidus (DI) is a disease characterized by excessive thirst, polydipsia and excess diluted urine caused by insufficiency of antidiuretic hormone or renal resistance to its effect. Although it is generally a benign condition, severe hypernatremia and hypertonicity may cause death if water loss is not compensated.Case report: A 72-years-old man admitted to our clinic for routine control. In medical history, he told that when he was...