Endocrine Abstracts

Introduction: Lower limb arterial disease (PAAD) is a serious complication of diabetes and is particularly common in patients at high cardiovascular risk. Its management in diabetic patients is a major public health problem, with sometimes tragic consequences for the patient. The objective of our work was to detect PAD in type 2 diabetics.Materials and Methods: This was a descriptive cross-sectional study involving 122 type 2 diabetics hospitalized at th...

Introduction: Protein-energy malnutrition appears frequently and early in course of chronic renal failure and represents a determining element of the morbidity and mortality. The objective of this study was to evaluate spontaneous food intake and to study the inflammatory profile of elderly people on hemodialysis.Materials and methods: This cross-sectional and descriptive study involved 40 elderly hemodialysis subjects. All patients underwent a complete ...

Introduction: Macronutrient intake in cancer therapy is a controversial subject. Low protein intake could lead to malnutrition and cachexia. This can affect the response to chemotherapy. To date, there are no clinical studies to answer this question. The aim is to assess the influence of different macronutrient intakes in breast cancer patients on the digestive tolerance of chemotherapy.Methods: This was a cross-sectional, descriptive study conducted ove...

Introduction : Obesity is undeniably a major factor in obstructive sleep apnea syndrome (OSAS). Diagnosis of the latter relies on polysomnography, but this test is not widely available. Screening of subjects at risk could be relevant, using tools such as the Berlin Questionnaire.Objective : To determine the prevalence of symptoms and risk factors for OSAS in a group of obese subjects.Methods: This was a cross-sectional study of 100...

Introduction: Malnutrition is a common issue observed in patients undergoing treatment for cancer. It stems from various factors and poses a significant challenge in the effective care of these individuals, adding complexity to their overall management. The aim of our study was to determine the prevalence of undernutrition and risk of undernutrition in women with breast cancer and its effect on chemotherapy digestive tolerance.Methodology: This was a cro...

Introduction: The most recent declared pandemic is attributed to COVID-19, caused by the novel coronavirus SARS-CoV-2. The angiotensin-converting enzyme 2, the principal receptor for SARS-CoV-2, exhibits expression in various tissues, prominently within gonadal and hypothalamo-hypophyseal domains. Long COVID, characterized by persistent symptoms post-infection, manifests in certain individuals and includes manifestations associated with the genitourinary system, such as sexual...

Introduction: COVID-19 is a viral infection that can affect various endocrine tissues, including the thyroid. In some patients, symptoms may persist after the infection, defined as Long COVID. Given the similarity of some of these symptoms to those encountered in thyroid disorders, we have decided to assess thyroid function in patients previously infected with SARS-CoV-2.Patients & Methods: This was a prospective study conducted from January to Decem...

Introduction: Obesity is one of the major public health issues worldwide and is known to be associated with an increased risk of severe metabolic and cardiovascular complication. The aim of our study was to assess the impact of obesity severity on the metabolic profile of obese patients.Materials and methods: Cross-sectional descriptive study involving 68 obese patients carried within the National Institute of Nutrition in Tunis. The patients were divide...

Introduction: Obesity is a major health problem through its numerous complications especially metabolic complications associated with cardiovascular risk. The aim of our work was to describe the clinico-metabolic profile of obese Tunisian adults.Methods: This was a descriptive cross-sectional study involved 174 obese patients who consulted between July and December 2020 at the Obesity Unit of the National Institute of Nutrition in Tunis. ResultsThe avera...

Introduction: In addition to its role in phosphocalcic metabolism, the vitamin D (vitD) seems to have anti-tumor effects, particularly in colorectal cancer (CRC). The active metabolite of vitD [1,25(OH)2D3], converted by the enzyme CYP27B1, inhibits proliferation and promotes differentiation of CRC cells which express vitamin D receptor (VDR) via the regulation of a high number of genes. The vitD metabolism seems also to regulate inflammatory processes in...