Endocrine Abstracts

We audited 46 pituitary MRI scans for patients with hypogonadotropic hypogonadism. We were particularly interested to see if adopting The Endocrine Society’s (TES) 2010 guidelines for Testosterone Therapy in Men with Androgen Deficiency Syndromes (pituitary MRIs only for those with testosterone level below 5.3 mmol/l, panhypopituitarism, persistent hyperprolactinaemia or if the patient has symptoms consistent with a mass effect such as headaches, a visual field defect or ...

Introduction: MElas syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes) is a mitochondrial disease conditioned by mutations in mitochondrial DNA and inherited in the maternal line.Case report: A boy, aged 9, with correct pregnancy II, birth weight 3450 g and of healthy, young parents was admitted to the Department of Endocrinology and Neurology, Medical University of LUblin in a severe condition, with left-sided hemip...

Background: Severe hyponatraemia and other electrolyte disturbances secondary to indapamide are documented in the literature. We report two cases that presented with neurological sequelae of profound hyponatraemia without seizures secondary to indapamide.Cases: An 86-year-old female presented with a history of confusion, vomiting and frontal headache associated with lethargy and anorexia. She had been started on indapamide 1 month earlier. She was on no ...

We present here the case of a 33-year-old woman, previously fit and well who presented initially with thyrotoxic symptoms. TFTs showed TSH <0.05, fT3 40. Thyroid uptake scan showed homogenous uptake of 8%. She was prescribed carbimazole 40 mg od and propanolol 40 mg bd with improvement.One month later, she presented to A+E with abdominal pain associated with diarrhoea and vomiting. She was found to be unwell, tachycardic and febrile. She had a global...

Objective: Diabetic ketosis is very often a reason for emergency consultation in diabetics. The objective of our study was to assess the etiologies of ketotic decompensations in diabetics.Methods: It was a descriptive cross-sectional study of 80 diabetics hospitalized at the National Institute of Nutrition for ketotic decompensation. Each patient underwent a clinical examination with a standard biological assessment.Results: The av...

Introduction: Secondary hypothyroidism is observed in children after brain damage. The aim of the study is evaluation of mental development in preterm-born children during replacement therapy with l-thyroxin because the secondary hypothyroidism. Description of methods: The motor and mental development preterm new-borns with secondary hypothyroidism treated with l-thyroxin since the second week of life were compared with the development of preterm new-bor...

Introduction: International recommendations prohibit fasting of the month of Ramadan in patients with diabetes, particularly unbalanced ones.The aim of our study was to describe the evolution of the glycemic balance in unbalanced diabetics with an HbA1C before the fasting greater than 10%.Patients and Methods: This is a descriptive evaluative study carried out on 25 patients with type 2 and with an HbA1C before fasting greater than...

Aim: The objective of our study is to describe the evolution of the parameters of the lipid balance after fasting in a population of diabetic women, and to determine if the BMI before the fast is associated with the variation of these parameters.Materials and methods: This is a prospective evaluative study conducted on 44 female patients with type 2 diabetes who have received prior education and therapeutic adjustment adapted according to the recommendat...

Introduction: After the fast of the month of Ramadan, the lipid balance of the elderly patients with diabetes can be modified. The aim of our study was to describe the evolution of the parameters of the lipid balance after the fast of Ramadan in a population of elderly diabetic subjects.Patients and methods: This is a prospective evaluative study conducted in a population of 20 patients with type 2 diabetes aged over 65 years. This population had benefit...

Introduction: Few studies have examined the adherence to anti–diabetic treatment in patients with diabetes during the fast of the month of Ramadan.The aim of our study was to describe the adherence to antidiabetic treatment in patients with diabetes before and during the fast.Patients and Methods: This is a descriptive and analytical study carried out on 140 diabetics who have fasted the month of Ramadan. The risk stratificat...