Endocrine Abstracts

Introduction: High blood pressure and type 2 diabetes are two pathologies that are often closely linked. The objective of our work is to determine the prevalence of hypertension and its effects on degenerative complications in a type 2 diabetic population.Methods: This is a retrospective study including 147 patients, followed at the Tunis National Institute of Nutrition for type 2 diabetes and comorbidities.Results: The mean age of...

Background and Aim: Obesity is a major risk for the development of hypertension. These cardiovascular risk factors are associated with nutritional targets. The aim of our study was to determine clinical characteristics, body composition and hypertension-related dietary patterns of obese patients with high blood pressure.Methods: This was a cross sectional study including 70 patiens. Clinical characteristics, anthropometric measures were collected. Body c...

Introduction: Trophic disorders of the diabetic foot and their complications represent a major public health problem. Treatment must be accompanied by quality therapeutic education to allow patients to self-manage their disease. The objective of this work is to evaluate, with the help of a questionnaire, the knowledge of diabetic patients on the diabetic foot.Materials and Methods: We conducted a descriptive, cross-sectional study among 50 diabetic patie...

Recurrent hypoglycemia is a major clinical problem. In fact, it disrupts blood glucose regulation and greatly impacts the daily lives of those affected. Maintaining glycemic balance is a real challenge indiabetic patients. The objectives of the study were to determine the prevalence of hypoglycemia in type 2 diabetics and to evaluate their knowledge.Patients and methods: This was a cross-sectional study conducted among 120 type 2 diabetic patients follow...

Introduction: Glucagonomas are rare functioning pancreatic neuroendocrine tumours that secrete glucagon. Gastrinomas are neuroendocrine tumours that secrete gastrin and are rarely located in the stomach. We report an extremely rare case of concomitant gastric gastrinoma and glucagonoma.Case presentation: A 64-year-old-man with a history of digestive haemorrhage and gastrectomy presented with weight loss, asthenia, anorexia and abdominal pain. Esophagogas...

Background: Insulinoma is a rare variety of endocrine neoplasm and is usually benign, solitary, and small in size. It is responsible of endogenous insulin secretion resulting in development of symptoms of hypoglycemia.Case presentation: We report 4 cases of insulinoma that were diagnosed and managed in the year 2022. Three women and one man aged respectively 76, 68, 60 and 42 years-old. All patients presented a long history of various adrenergic symptoms...

Background: Adrenocortical carcinoma is a rare malignancy with a poor prognosis. Local recurrence is affected by the pathologic features (tumor staging and mitotic index) and the complete surgical resection. Treatment of a recurrent adrenocortical carcinoma can be a real challenge.Case description: We report a case of 47-year-old man who was operated for an adrenal tumor with bone metastases. Left adrenalectomy and splenectomy were performed and histolog...

Introduction: Growth hormone deficiency (GHD) is a rare cause of delay of growth. However, it is primordial to screen for it since its presence leads to a specific treatment which improves statural prognosis. GHD should be confirmed through stimulation tests such as Insulin Tolerance test (ITT) or Clonidine Stimulation Test (CST). The objective of our study was to compare these two diagnostic tools.Methods: We conducted a retrospective study in the endoc...

Introduction: Cushing’s disease (CD), a hypercorticism caused by an ACTH-secreting pituitary adenoma, was associated with a 5-year survival of only 50%. Although advances in management have significantly reduced mortality, the results of transsphenoidal surgery, the gold standard in the treatment of CD, vary from patient to patient.Objective: The aim of our study is to evaluate the results of transsphenoidal surgery in CD (evolution, complications) ...

Non-secreting pituitary adenomas (NSPA) are relatively rare benign tumors their prognosis depends essentially on their endocrine and ophthalmological repercussions the aim of our study is to outline their clinical, biological, radiological aspects, and the therapeutic choice.Methods: Retrospective study of 17 patients with non secreting pituitary adenomas.Results: We identified 17 patients with NSPA split into 12 women and 5 men wi...