Endocrine Abstracts

Introduction: Dopamine agonists are commonly used for the treatment of Parkison’s disease and prolactinomas. Sometimes high doses are needed in mixed pituitary adenomas. This medical treatment usually induces gastrointestinal troubles and/or low blood pressure, and sometimes psychiatric disorders. Pleuropercarditis effusion (PPE) is rarely related to dopamine agonist side effects.Case report: Our aim is to report a man aged 29 years old whose PPE is...

Background and objectives: Certain diseases, such as multiple endocrine neoplasia type 2A (MEN2A), MEN2B, familial and sporadic medullary thyroid carcinoma (MTC) and renal dysgenesis are related to abnormalities of the RET protein. Our aim was to evaluate the frequency of RET mutation in ten Saudi families with MEN2A and familial medullary thyroid carcinoma.Design and setting: Cross-sectional prospective study of patients followed up at King Abd...

Objective: The objective of this study was to investigate the correlation between the neurological manifestations of Vitamin D deficiency and the levels of 25(OH) D and bone profile.Methods: We conducted a case series study in patients with osteomalacia who were followed up at King Abdulaziz Medical City, Jeddah, between January 2010 and December 2011. We collected information on demographic data, etiological factors for Vitamin D deficiency, clinical pr...

Introduction: Pituitary hyperplasia (PH) is relatively a rare condition in children. As in adults, it can be secondary to a long-standing primary hypothyroidism and can sometimes be mistaken with a pituitary macro-adenoma as in the following observation:Case report: Herein, authors describe a girl aged 10 years old sent by her neurosurgeon for pre operative hormonal exploration of a pituitary macro adenoma measuring 13 mm in height. This one was discover...

A 53 year-old woman presented with labile and difficult to control hypertension on three deferent anti hypertensive medications. Abdominal computed tomography (CT) and Ultrasonography of the thyroid gland showed 1.8 cm thyroid nodule. Fine needle aspiration biopsy of the thyroid nodule revealed papillary thyroid carcinoma. Serum TSH & FT4, calcitonin, CEA, intact PTH and calcium levels were within normal limits. A 24-h urine metanephrines showed significant elev...

Introduction: Adrenal metastases used to be rare in endocrinology compared to others adrenal tumours, and deemed to have a dire prognosis. Our aim is to analyze 13 cases in order to study their morphological aspects, their causes, and their outcome.Subjects and method: Thirteen cases were studied over a long period of time (2000–2012). All of them had biological, hormonal, and radiological assessments.Results: We had ten men a...

Introduction: Congenital trans-sphenoidal meningocele (TM) is a rare clinical entity. It can be traumatic, congenital or from tumour origin. It results from a defect in the sphenoid bone ontogenesis. In its classical form, the TM is revealed in adults, frequently in women in the fourth or fifth decade by rhinorrhea or cerebrospinal fluid leak through a bony defect in the sphenoid floor. Our aim is to report a case of large TM without rhinorrhea, and as a part of midline abnorm...

Objective: To evaluate pheochromocytoma that occurs in Saudi patients with MEN 2APatients and methods: Of 44 patients belonging to 5 MEN 2A families, 14 (31.8%) presented with pheochromocytoma. The following variables have been studied: clinical and diagnostic data (age, mutation, clinical features, and laboratory studies included measurements of 24-h urinary catecholamines, epinephrine, metanephrine, norepinephrine, dopamine, vanillylmandelic acid, and ...

A 40-year-old male presented with blackouts. This was associated with transient loss of consciousness with complete subsequent recovery. He did not have any warning signs, tongue biting or urinary incontinence. There was no history of alcohol or elicit drug abuse. He was admitted to MAU.Past medical history: HIV diagnosed 18 months previously. Cutaneous and oral Kaposi’s sarcoma successfully treated with chemotherapy. Hepatitis C, asthma.<p clas...

Introduction: The occurrence of primary pituitary tumour and cerebral schwannoma in the same person is very rare. Only few cases have been reported so far. The mechanism of this association is still unclear.Aim: Our aim is to report a man with two different brain tumours: a prolactinoma and a cerebellopontine schwannoma in order to discuss the possible mechanism of multiple neoplasms arising in the same person.Case report: A man ag...