Endocrine Abstracts

Adrenocortical tumorigenesis has been observed in mice. It is speculated to be gonadotropin dependent. In particular LH receptors appear to be found within such adrenal tumors in high density and elevated LH levels may be related to adrenal tumorigenesis. The aim was to describe the case of a patient who after ovariectomy developed a large malignant adrenal tumor. A patient, female, aged 42 presented with uterine leiomyomas. She was treated by surgical excision of the uterus a...

Osteoporosis is a bone disease predisposing to bone fragility. Nowadays, the population is screened for osteoporosis and measures are taken for fracture prevention. Additionally, people are urged to have a diet rich in calcium, are given calcium supplements and are being treated for vitamin D deficiency. Moreover, osteoporosis treatment is administered. Therefore, the relationship between osteoporosis and fractures in the real world setting is very interesting.<p class="ab...

Primary hyperparathyroidism is a disease which nowadays is being diagnosed with increasing frequency. The diagnosis of primary hyperparathyroidism is based on routine calcium measurement, which if detected abnormally elevated leads to the screening of the patient for primary hyperparathyroidism. Therefore, primary hyperparathyroidism is frequently detected early in the course of the disease. Consequently, severe musculoskeletal manifestations may be lacking in the modern world...

Thyroid cancer is the most frequent endocrine cancer. Its incidence has been found to increase in recent years. Additionally, environmental factors, which may be implicated in the pathogenesis of thyroid disorders, such as iodine deficiency and salt iodine supplementation are changing and may have an impact on the epidemiology of thyroid cancer. The aim was to study the epidemiology of thyroid within a center of excellence in Athens in the modern world setting. A cohort of 63 ...

Introduction: Neurofibromatosis type 1 or von Recklinghausen disease is a systemic hereditary disease characterized by disorders regarding the skin, neural and skeletal systems. Osteoporosis is one of the skeletal manifestations of neurofibromatosis type 1, being associated with increased fracture risk. Neurofibromatosis type 1 is associated with a propensity for the development of cancer, breast cancer in particular being associated with neurofibromatosis type 1.<p class=...

Introduction: The anticancer action of vitamin D is currently considered one of its main properties. The main actions of vitamin D are related to the regulation of calcium levels and the normal function of the musculoskeletal system. However, its anticancer action is currently in the focus of research interests.Aim: The aim was to study the effect of vitamin D on MCF-7 human breast cancer cells in vitro.Methods: The effect...

Introduction: It has been reported that blind women with disturbed melatonin secretion have a lower incidence of breast cancer. A higher incidence of breast cancer has been reported in women in shift work, in which lower nocturnal melatonin secretion is observed. The anticancer action of melatonin is currently the focus of research interest.Aim: The aim was to study the effect of melatonin on MCF-7 breast cancer cells in vitro.<p class="abst...

Introduction: Melatonin is an indole being produced by the pineal gland and secreted mainly during the night. Melatonin is involved in the regulation of biological rhythms. The hormone possesses antioxidant action and is thought to be involved in the protection of the organism from the development of malignant tumors. Melatonin has been found to have anticancer action in vitro as is has been observed to inhibit the proliferation of cancer cells in vitro.<...

Introduction: Patients with autoimmune diseases are known to develop other autoimmune conditions. Adrenal insufficiency of autoimmune etiology is known to coexist with autoimmune diabetes mellitus, Hashimoto’s thyroiditis and vitiligo. However, Graves’ disease in the context of adrenal insufficiency of autoimmune etiology is rare.Aim: The aim was to describe the case of a patient who presented with fatigue and was diagnosed to have hyperthyroid...

: Postmenopausal osteoporosis is a common condition affecting many women. Management of postmenopausal osteoporosis involves the administration of vitamin D, calcium and antiresorptive agents. The long-term management of postmenopausal osteoporosis with antiresorptive agents may present some dangers and adverse effects such as bone necrosis or atypical bone fractures.Case report: The aim was to describe the case of a female patient with postmenopausal ...