Endocrine Abstracts

Introduction: Adrenal schwannomas are very rare tumors that are difficult to diagnose properatively. They represent only 1–3% of all retroperitoneum masses.Case report: A 30-year-old woman was referred to the outpatient to evaluate an adrenal mass incidentally found on abdominal ultrasonographic images obtained for self-limit abdominal pain. Her medical and family histories were unremarkable. Clinically asymptomatic, only referred amenorrhea for two...

Introduction: Salivary cortisol measurement is a non-invasive and easy test to carry out. It is painless and does not cause stress.Aim: The aim of the present study was to evaluate the correlation between salivary cortisol (SaC) and serum cortisol (SeC) after 1 mg Dexamethasone (DXM) overnight and their diagnostic utility as screening test of Cushing’s syndrome (CS).Methods: We performed a prospective study in 92 patients with...

Introduction: Recently we have demonstrated the contribution of the quantification of expression of adenohypophyseal hormone genes in the identification of the different Pituitary Neuroendocrine Tumor (PitNET) subtypes according to the 2004 WHO criteria.Aim: The aim of the present study was to evaluate the contribution of the quantification of expression of pituitary transcription factor genes to the identification of PitNETs according to 2017 WHO criter...

The improvement of glycemic control and body weight reduction by GLP-1 receptor agonist (GLP1RA) has been demostred in randomized clinical trials, but comparative studies of the efficacy of different GLP1RA in real world and clinical practice setting are limited.Objectives: To compare the efficacy of liraglutide (LIRA), exenatide once weekly (EQW), and lisixenatide (LIXI) treatment in a real-world and clinical practice setting.Meth...

Ghrelin is a 28-aa peptide originally isolated from stomach but present also in many tissues, including hypothalamus and pituitary, where it stimulates growth hormone (GH) release through the ghrelin/GH secretagogue receptor (GHS-R). Ghrelin also increases food intake and adiposity and could play a key integrative role in the endocrine–metabolic interface. Although its primary pituitary cell target are somatotropes, ghrelin also modulates other pituitary cell types, speci...

Introduction: Post-stroke hyperglycemia affects two-thirds of the patients during acute ischaemic stroke and it is associated with poorer outcomes. The aim of this study was to analyze the differences between the diabetic and non- diabetic patients that underwent an acute stroke.Methods: Retrospective descriptive study of patients admitted to the Acute Stroke Unit from January to June 2017, including blood parameters, glycemic treatment and 3 months outc...

Introduction: Autoimmune Thyroid Diseases (AITD) are one of the most prevalent autoimmune diseases in industrialized countries (5% of population). The two main phenotypes of AITD, Hashimoto thyroiditis (HT) and Graves’ disease (GD), are both characterized by the presence of circulating thyroid antibodies and infiltration by autoreactive lymphocytes in the thyroid gland and sometimes the orbit. One of the most studied mechanisms underlying AITD is the imbalance between imm...

Objective: Recent reports have suggested that air pollution may impact thyroid function, although the evidence is still scarce and inconclusive. In this study we evaluated the association of exposure to air pollutants to thyroid function parameters in a nationwide sample representative of the adult population of Spain.Methods: The [email protected] study is a national, cross-sectional, population-based survey which was conducted in 2008-2010 using a random clust...

Introduction and Aims: Thyroid lesions constitute a frequent consultation in the area of endocrinology. Fine-needle aspiration (FNA) cytology is a gold standard for the evaluation of thyroid lesions, while ultrasound examination according to various thyroid imaging reporting and data system (TIRADS) criteria is gaining importance in the field. The aim of our study was to compare the sensitivity and specificity of both techniques in patients attended in thyroid lesion unit of o...

Objective: The objective of our study is to evaluate muscle strength and risk of falls in type 2 diabetes mellitus (DM2) patientsMethods: Observational cross-sectional study. Hand grip strength (HGS) (kg/cm2) was measured with a Jamar. manual hydraulic dynamometer (5030j1; Jackson, MI). To classify normality, data from the Spanish population were used, establishing the cut-off point at p10. To assess the level of mobility and the risk of ...