Endocrine Abstracts

Introduction Hypothyroidism (HT) is widespread in all age groups particularly within the increasing elderly population while its diagnosis is challenging owing to extremely varied and atypical symptoms. The objective of this study is to outline the clinical and biochemical features of HT and determine its main etiologies in a geriatric population. Methods We reviewed the medical charts of 53 patients aged 65 ...

IntroductionCardiothyreosis is the most dreadful complication of hyperthyroidism. In Tunisia, cardiothyreosis has rarely been analyzed. The aim of our study was to describe the clinical aspects of this disease in an adult population of southern Tunisia.MethodsRetrospective study (January 1999 to December 2018) including all cases of hyperthyroidism with cardiothyreosis followed in our department.<p class=...

BackgroundAmiodarone is a widely-used anti arrhythmic medication. Amiodarone-induced hyperthyroidism (AIH) develops in 3% of amiodarone-treated patients. AIH is classified as type 1 or type 2. Type1 AIH occurs in patients with underlying thyroid condition while Type2 AIH is a result of amiodarone causing a subacute thyroiditis. Appropriate therapy for amiodarone-induced hyperthyroidism requires a careful diagnosis that may be difficult to achieve.<p ...

IntroductionRecent studies in patients with Addison’s disease (AD) have shown that this condition, even if treated, is fraught with significant morbidity. In this context, we report a retrospective study which concerned 32 patients with AD in order to determine the deleterious effects of long-term glucocorticoid substitution, mainly on the occurrence of type 2 diabetes.ResultsIn the 32 patients followed ...

IntroductionAdrenal tumors represent an increasingly common problem in modern endocrine practice. The diagnostic approach can be challenging and occasionally reveals surprising features like mixed hormonal secretion: aldosterone-and-cortisol producing adenoma. This rare situation can also impact on the therapy and the post-operative management. In this context, we report 5 patients who are followed in the Endocrinology department in Hedi Chaker hospital,...

IntroductionMetabolic syndromeis the association in the same individual of a number of cardiovascular risk factors, namely abdominal obesity, dyslipidemia, high blood pressure and glucose intolerance. The objective of this study is to analyze the clinical and paraclinic characteristics of obese and overweight children in order to look for the elements of metabolic syndrome in these childrenMethodsWe carried o...

IntroductionThe diabetic foot represents a public health problem with very important direct and indirect expenses. Multidisciplinary care and monitoring is essential. The aim of this Study was to describe the management of the diabetic foot in the endocrinology department.Materials and methodsIt was a retrospective study carried out in the Endocrinology and Diabetology department of the Hédi Chaker unive...

IntroductionNon alcoholic steato-hepatitis (NASH) is the most common chronic liver disease in developed countries rare in type 1 diabetes it is associated with an increased risk of complications in patients with type 1 diabetes mellitus (T1DM). The aim of this study is to clarify the characteristics of NASH in patients with T1DM.Materials and methodswe conducted a retrospective descriptive study in non-alcoho...

INTRODUCTIONType IV hypertriglyceridemia (HTG IV) or endogenous HTG is a rare inheriteddisorder of the lipoprotein metabolism due to increased hepatic triglyceride synthesis(TG). Although HTGIV is not usually expressed until adulthood, it might be unmasked earlier. We report the case of an early and severe HTGIV complicated with chronic pancreatitis.Case reportA 6-year-old childwith no particular history was ...

IntroductionType 1 Diabetes (T1D) diagnosed during adulthood is a form of diabetes which is underdiagnosed and underreported. Lower incidence of cardio metabolic risk factors such as atherogenic dyslipidemia, high blood pressure and obesity have been reported in T1D patients compared to type 2 diabetes. In this study, we aimed to determine the prevalence of and predictive factors for macrovascular complications during T1D diagnosed in adulthood.<p cl...