Endocrine Abstracts

Paragangliomas (PGL) and pheochromocytomas (PHEO) are rare neuroendocrine tumors with an estimated prevalence of 1:6500 and 1:2500, respectively. Although most PGL/PHEO are benign, approximately 10% of PHEOs and 15-35% of PGLs have metastatic disease, which it is main cause of death, with 6 years of median survival. Objective: To characterize the metastatic PHEOs and PGLs from a single center. Methods: Retrospective analysis of clinical records of patients with metastatic PHEO...

Background: Both cortisol and other adrenal hormones are well known to affect brain structure and function throughout development. Due to destruction of the adrenal cortex, patients with Autoimmune Addison’s disease (AAD) lack production of adrenal hormones and therefore receive lifelong replacement of cortisol and aldosterone, and, for some female patients dehydroepiandrosterone (DHEA). However, replicating the natural rhythm of secretion is difficult, and patients are o...

Background: Male osteoporosis is undermanaged. The characteristics of men referring to health care system for bone evaluation remain partially unknown.Aim: To characterize from real-life data male patients seeking the first bone health evaluation at a tertiary academic medical center, referral for both andrological and bone diseases, over a 13-year observation period.Methods: Retrospective, cross-sectional study, including adult me...

Very Low-Calorie Ketogenic Diet (VLCKD) is currently a promising approach for the treatment of obesity. However, little is known about the side effects since most of the studies reporting them were carried out in normal weight subjects following ketogenic diet for other purposes than obesity. Thus, the aims of the study were: 1) to investigate the safety of VLCKD in subjects with obesity; 2) if VLCKD-related side effects could have an impact on its efficacy. In this prospectiv...

Introduction: The COVID-19 pandemic has presented many challenges in the management of diabetics around the world. While many people can be managed using new methods such as tele-consulting, the diabetic foot presents unique challenges due to the frequent need for “face-to-face” consultation and treatment. The pandemic has thus made the management of diabetic feet, already complex, even more difficult. This study aims to assess the impact of the COVID-19 pandemic on ...

Introduction: Diabetic foot ulcer (DFU) is one of the major complications of diabetes mellitus. It can be a cause of amputation. A multidisciplinary approach is essential to promote wound healing and decrease amputation rates. Epidermal growth factor (EGF) is used as an adjuvant to close the wound in addition to standard care in diabetic foot ulcers.Methods: This is a prospective study carried out between February 2019 and April 2021 in the department of...

Introduction: The COVID 19 pandemic is causing a considerable degree of fear and concern among the general population. In diabetic pregnant women, this risk is even higher given the physiological and psychological changes that occur during pregnancy.Goal of the study: To evaluate the prevalence and risk factors for the onset of anxiety-depressive disorders in pregnant women with diabetes during the COVID 19 pandemic in comparison with those followed outs...

Struma ovarii is a form of mature teratoma, a rare germ cell tumor, containing more than 50% thyroid tissue. Malignancy is uncommon. Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) inside struma ovarii was never described. A 32 y.o. female with previous history of ovarian cysts was admitted in the emergency room with painfull acute abdominal distention. The MRI revealed a right adnexal mass, predominantly cystic with 82x66x80 mm and surrou...

Introduction: 17 alpha-hydroxylase deficiency (17OHD) is a rare autosomal recessive disease caused by mutations in the CYP17A gene, representing 1% of cases of Congenital Adrenal Hyperplasia (CAH). The accumulation of mineralocorticoids and the glucocorticoid effect of corticosterone induce high blood pressure (HBP) and hypokalemia.Clinical Case: A 44 year-old female reporting HBP since the age of 20 years and without chronic medication, presented at the...

Introduction: The update of 2015 American Thyroid Association (ATA) guidelines recommend that radioactive iodine (RAI) ablation therapy should be used in line with patients’ risk stratification. However, there is no consensus on benefits of post-operative RAI ablation in patients with low risk differentiated thyroid cancer (DTC). The aim of this study is to compare the outcomes of patients with low risk DCT submitted to RAI ablation with those who were not.<p class="a...