Endocrine Abstracts

Introduction: Pretibial Myxedema(PM) and acropachy(AP) are rare extrathyroidal manifestations of Graves’ disease observed only in 0.5–4% of all cases. These extrathyroidal manifestations are generally associated to severe ophtalmopathy. Only few cases of severe thyroid dermopathy and achropachy occurring with moderate ophtalmopathy were reported.Observation: We present a 60years old female patient who developed grave’s disease on a pre-exi...

Introduction: Neoplasias in the thyroglossal duct cyst (TDC) are rare, their prevalence varies from 1 to 1.5%. The most common cancer is papillary cancer representing 85% of cases. The diagnosis is often fortuitous following to the anatomopathological examination of the surgical specimen.Patient and method: Our patient has 33-years-old, with no previous medical history, which underwent a resection of a TDC of 29 mm in diameter, diagnosed by an anterior c...

In recent years non-alcoholic fatty liver disease (NAFLD) has been ascribed to conditions associated with the metabolic syndrome (MS). The high probability of an unfavorable course of NAFLD combined with MS symptoms dictates the need to search for some therapeutic approaches in the treatment of patients, given the similarity of the development mechanisms of both MS and NAFLD, i.e. the insulin-resistance. One of the drugs that reduces insulin resistance is Subetto (Subetta, NPF...

Aim: to study features of growth and development in teenagers with Diabetes Insipidus of central genesis.Material and methods: During 2009–2010 years we examined 37 teenagers with Diabetes Insipidus of central genesis. 19 boys (51.3%) and 18 girls (48.6%) among them. Mean age of boys and girls was 13.5 years.All patients underwent general clinical examination. Levels of STH, LH, FSH, prolactin, TSH, free thyroxin, cortisol, et...

Non-islet cell tumour hypoglycaemia (NICTH) is a rare paraneoplastic phenomenon and there is limited guidance regarding different treatment modalities.We present two cases of NICTH focusing on the combined methods used to control hypoglycaemia.The first involves an 89-year-old gentleman diagnosed with a pelvic leiomyoma in 2003. For several years, he had experienced recurrent collapses which briefly improved following tumour emboli...

Introduction: Adrenal insufficiency is rarely diagnosed during pregnancy. In the absence of treatment it is associated with high maternal-foetal morbidity and mortality. We report the case of a twenty-one years old female patient, diagnosed with adrenal insufficiency during a diabetic pregnancy of 12 weeks of gestation.Observation: Twenty-one years old female patient, diagnosed with type 1 diabetes since the age of 15, Referred to our department for the ...

Introduction: Dupuytren’s disease (DD) corresponds to a chronic palpable thickening of the palmar aponeurosis which leads to different degrees of irreducible flexion of the fingers. It is one of the manifestations of hand syndrome in diabetes mellitus. We highlight through this report the occurrence of DD as a manifestation of diabetic hand syndrome in a patient with type 2 diabetes mellitus.Observation: A sixty-six year old patient, truck driver, t...

Introduction: Type 2 diabetes is an important risk factor for all forms of infection. It may be unrecognised for many years, and often revealed by degenerative or infectious complications. The aim of this study is to investigate the epidemiological, clinical and therapeutic aspects of severe infections revealing type 2 diabetes.Patients and Methods: Retrospective descriptive cross-sectional study of a series of 5 patients with severe infections revealing...

Introduction: Human immunodeficiency virus (HIV) infection and certain antiretroviral (ARV) treatments are associated with an increased risk of developing certain chronic comorbidities including type 2 diabetes, which is more prevalent in HIV-infected individuals. The coexistence of diabetes and HIV infection makes the standard of care more complex. The objective of this work is to discuss the relationship between these two comorbidities and to update physicians on the diagnos...

Introduction: Polyuro-polydipsia syndrome (PPS) is defined by urine excretion rate more than 3L per day, associated with a parallel increase in oral fluid intake. It poses problems of positive and etiological diagnosis. We discuss in this observation the modalities of exploration of PPS and its main etiologies.Case report: A 60-year-old patient, diabetic for 10 years, controlled on metformin, admitted for PPS evolving for 37 years. Clinical examination w...