Searchable abstracts of presentations at key conferences in endocrinology

ea0050p364 | Reproduction | SFEBES2017

Aortic dissection in Turner syndrome: a single centre experience

Calanchini Matilde , Myerson Saul , Turner Helen , Orchard Liz

Introduction: The risk of aortic dissection (AoD) is significantly increased (40 per 100,000/y) in women with Turner Syndrome (TS), but the clinical profile and management for those at risk are not well-established. To gain a better understanding, we present the experience of a single centre with multidisciplinary care, including dedicated cardiology, for management of TS in adulthood.Methods: Retrospective case-review of women develop...

ea0086p276 | Reproductive Endocrinology | SFEBES2022

Is there a consensus for Management of Hormone Replacement for Males and Females with Hypogonadism in the UK? SfE national survey

Al-Sharefi Ahmed , Quinton Richard , Turner Helen E

Background: Optimization of sex hormone replacement therapy (SHRT) is essential in long-term management of patients with hypogonadism. However, approaches to formulations of therapy, dose change (if any), monitoring of adequacy of therapy and safety are not standardised.Objectives: The survey aimed to establish the approach to management of SHRT for male and female hypogonadism.Methods: Online survey, live for 4 weeks (1/11/2021) d...

ea0065p141 | Endocrine Neoplasia and Endocrine Consequences of Living with and Beyond Cancer | SFEBES2019

Predicting hypophysitis in patients treated with immune checkpoint inhibitors: can prolactin be used as a marker of incipient disease?

Noronha Sean , Pueyo Maria , Payne Miranda , Turner Helen

Background: Immune checkpoint inhibitors (ICIs), approved in the UK for the treatment of increasingly numerous malignancies, are commonly associated with endocrine sequelae, some of which may be life threatening. Society for Endocrinology guidelines detail management protocols for acute endocrinopathies, however widely accepted standards for their routine detection are lacking. Hypophysitis, clinically and radiologically silent in many, is seen in up to 15% of patients on ICIs...

ea0065p338 | Nursing practice | SFEBES2019

Cortisol alert dog: Improving patient outcomes?

Loo Helen , Marland Anne , Shoosmith Zara , Turner Helen

Introduction/Aim: In Addison’s disease, patient-self maintenance of adequate cortisol levels is essential. Optimising cortisol control is challenging and well documented. Traditional management aims to ensure adequate daily cortisol levels, management of stressful situations/acute illness, avoiding over replacement. Alert dogs are currently used to support patients with hypoglycaemia unawareness. Recent reported international studies of alert dogs in primary and secondary...

ea0065p354 | Reproductive Endocrinology and Biology | SFEBES2019

Maternal cardiovascular risk and pregnancy outcomes in turner syndrome – new evidence supports current guidance

Calanchini Matilde , Bradley-Watson James , Orchard Elizabeth , Turner Helen E

Introduction: The risk of maternal death from aortic-dissection(AoD) during pregnancy/post-partum in TS is increased, due to TS-associated risk factors (bicuspid-aortic-valve(BAV), aortic-coarctation, aortic-dilatation, hypertension) and the increased cardiovascular strain of pregnancy itself. TS-guidelines advice against pregnancy in the presence of severe aortic-dilatation or moderate dilatation with AoD-risk factors; and after aortic surgery a high risk remains. However, fe...

ea0049gp206 | Thyroid 2 | ECE2017

Early use of steroid-sparing agents in treatment of moderate-to-severely active thyroid eye disease

Sipkova Zuzana , David Joel , Turner Helen , Norris Jonathan

Introduction: The management of active thyroid eye disease (TED) remains controversial. High dose intravenous methylprednisolone (IVMP) is the current recommended first-line treatment based on EUGOGO guidance. Such therapy has the potential for serious adverse effects. We present the outcomes of an alternative approach in the management of moderate-to-severely active TED, using steroid-sparing agents (SSAs) in conjunction with IVMP. Methotrexate is used as the first-line SSA a...

ea0038p176 | Nursing practise | SFEBES2015

Utilisation of nurse led clinics in endocrinology practice

Shepherd Lisa , Marland Anne , Austin Rachel , Turner Helen

Since the introduction of the reduction in hours for junior doctors in 1991, nurse led clinics (NLC) have increasingly become embedded into specialist practice. Whilst some NLC such as Diabetes and Respiratory have been established for many years, in the area of Endocrinology they are a newer evolving concept.Currently there is limited research in this area. An online survey was distributed to 98 nurse members of the Society for Endocrinology. The questi...

ea0038p178 | Nursing practise | SFEBES2015

Pre-pituitary surgery patient satisfaction audit 2015

Thornton-Jones Vivien , Turner Helen , Cudlip Simon , Grossman Ashley

Background: Pre-pituitary surgery, patients attend a ‘Pre-Pituitary Surgery Clinic’ (PPSC), to discuss management options and risks. Clinicians in attendance are; pituitary surgeon (1) registrar (1) endocrine team consultants (1–3), registrars (1–2) nurses (1) senior house officer (1) visiting doctors/medical students (4–6). Patients are informed a number of clinicians attend the clinic due to the multidisciplinary nature (MDT) and unit teaching respon...

ea0056gp260 | Thyroid non cancer - Autoimmune Thyroid disease/pregnancy | ECE2018

Early low dose rituximab for active thyroid eye disease: an effective and well tolerated treatment

Insull Elizabeth , Turner Helen , David Joel , Norris Jonathan

Background: Thyroid eye disease (TED) is an autoimmune inflammatory disease that can be both disfiguring and potentially sight threatening. Suppression of inflammation in active disease can reduce the risk of visual loss and limit long-term sequelae of the disease. Current disease management involves suppression of inflammation using glucocorticoids. The aim of our study was to evaluate the efficacy of early disease intervention with targeted immunomodulatory therapy to alter ...

ea0094p154 | Nursing Practice | SFEBES2023

Improving collaboration between endocrine patient support groups and the society for endocrinology

Breen Louise , Smith Vick , Okoro Grace , Turner Helen

Background: Patient Support Groups (PSG) play a key role in the support, education, research and training for patients and clinicians alike, as well as providing invaluable input to key documents e.g. Defining the Future of Endocrinology (DfE), highlighting the importance of a closer working relationship with SfE.About the PSG Network: Established in Sept 2021, the network includes representation from SfE affiliated PSG ...