Endocrine Abstracts

Introduction: Clinical trials have show n that improved glycemic control reduces the incidence and progression of diabetes complications. One of the most important steps in diabetes treatment is to educate patients how to manage self monitorining blood glucose (SBGM) and adjust their life habits with their diabetes. A new diabetes management concept of structured testing is supported by Accu -Chek 360 View.Objectives: Assess the impact of structured test...

Background and aims: Acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV). The therapy with antiretroviral drugs is associated with increasing reports of metabolic abnormalities such as body fat abnormalities, impaired glucose metabolism and insulin resistance, dyslipidemia. We investigated the prevalence of diabetes mellitus in patients with AIDS in treatment with antiretroviral drugs.<p class="...

Aim: An increasing proportion of patients are referred to endocrine clinics for assessment of an endocrine reason for obesity. The aim of our study was to assess the hormone profiles of patients referred for bariatric surgery.Methods: Patients referred to bariatric surgery clinic were investigated for hypothyroidism (TSH, T4), Cushing’s disease (2 mg-overnight dexamethasone suppression test), acromegaly (IGF1) and Vitamin D deficiency (PT...

The aim of the present study was to examine the role of steroid hormones in control of growth and obesity. We have measured plasma level of progesterone (P4), testosteron (T) and estradiol (E2) in 301 adolescent girls at different stages of their ovarian cycle, and compared they with standard morphometric indexes of their growth and obesity – body height, body mass, abdomen and hip circumstances and waist to hip ratio (WHR). The ovarian cycle-depende...

A 75-year-old man was admitted acutely with a 1 week history of headaches, reduced visual acuity, diplopia and ptosis of his left eye. Examination confirmed a left III and VI nerve palsies with decreased visual acuity in the left eye. A CT and subsequent MRI revealed pituitary mass lesion measuring 2.4×2.1×1.5 cm with extension into the left cavernous sinus. The pituitary stalk appeared thickened and was deviated to the right. The optic apparatus was uninvolved.<...

Background: The incidence of type 1 diabetes mellitus is increasing worldwide with recent European data suggesting annual increases ranging from 0.6 to 9.3%, the overall rate being 3.9%. It was thought that the Republic of Ireland (ROI) had one of the lowest disease incidences in Europe. The first Irish study of T1DM incidence which provided a measure of case ascertainment, confirmed a high incidence rate (IR) at 16.6 per 100 000 placing this population, in the upper quartile ...

The hypothalamo-pituitary–thyroid (HPT) axis serves to maintain appropriate systemic levels of thyroid hormone (TH) through a negative feedback pathway via the hypothalamic arcuate and paraventricular nuclei. However, the effects of TH in other hypothalamic regions are poorly understood. Triiodothyronine (T3) administration to the hypothalamic ventromedial nucleus (VMN) induces a potent hyperphagic response, although it is unclear whether this is part of a nove...

Introduction: There has been an increasing trend towards outpatient and short stay surgery in UK in last 20 years. This leads to reduced costs, reduced inpatient waiting lists, increased availability of inpatient beds and has the psychological benefit of avoiding prolonged hospitalisation.We liked to evaluate the feasibility of day case and short stay surgery for parathyroid disease in our district general hospital.Material and method: It was retrospecti...

Introduction: Tc 99m sestamibi scan and ultrasound are been used most frequently than other imaging technique in the pre operative localization of parathyroid gland in primary hyperparathyroidism. We liked to evaluate our hospital experience with the scan in preoperative localization of the glandular disease.Method and material: It was a retrospective audit of 7 years from 2000–2007 of 48 patient who underwent open explorative procedure by single su...

Background: Primary hyperparathyroidism (PHPT) is nowadays an asymptomatic disease characterized by mild hypercalcemia and elevated parathormone (PTH) levels. PHPT is caused by parathyroid adenoma in 80–85% of patiens, up to 20% are located ectopically and therefore an ultrasound investigation is not helpful. SPECT sestamibi or tetrofosmin scintigraphy of the neck and thorax is considered to be the optimal method for the evaluation of ectopic parathyroid adenoma.<p cl...