Endocrine Abstracts

Familial pheochromocytoma is inherited as a component of one of 5 pheochromocytoma – related syndromes such as von Hippel-Lindau disease, multiple endocrine neoplasia type 2 and the paraganglioma syndromes type 1 and type 4.Neurofibromatosis type 1 is often cited as the fifth of these syndromes but a clinical-genetic characterisation does not exist. 0.1 to 5.7% of patients with neurofibromatosis type 1 have pheochromocytoma. The NF1 gene as the susc...

Background: An adrenal incidentaloma is defined as an adrenal mass larger than 1 cm, detected on imaging performed for an indication other than evaluation of adrenal disease. Following the European Society of Endocrinology clinical practice guideline, assessment of malignancy by imaging and hormone excess should be done simultaneously(1). To investigate whether an adrenal mass is functionally active, a thorough clinical examination is required, extended with a 1mg o...