Endocrine Abstracts

Background: Surgery which was until sixty years ago the only treatment available for Graves’ disease (Gd) is now the last recommended therapeutical option, the number of thyroidectomies (Tx) being in continous decrease. American physicians prefere radioiodine use while their European and Japanese colleagues like better long-term administration of antithyroid drugs.Patients and methods: A retrospective study carried out on 52 consecutive patients wit...

Background: Parathyroid carcinoma (PC) is a rare endocrine tumour, with difficult intraoperative recognition, histological diagnosis and imprevisible evolution. More unusual are the cases appearing at the patients with end-stage renal disease on maintenance hemodialysis (22 observations in medical literature).Case report: A 46 year-old man which suffered of chronic glomerulonephritis from 13 years, being on hemodialysis from three years, complains of ast...

Background: Concomitent occurrence of primary (PHPt) or renal (RHPt) hyperparathyroidism and papillary thyroid microcarcinoma (PTMc) is rarely described in literature.Patients and methods: Between 1986 and 2010 sixtythree subjects undewent operations for PHTp (n=20) or RHTp (n=43) in our clinic. In three cases (4.7%) a synchronous PTMc was intraoperatively discovered.Results: First case, female – 56 years old pre...

Introduction: The significant increase in the average lifespan of the general population lead to a proportional enhancement in the prevalence of benign and malignant thyroid conditions and equally the number of surgeries for this pathology.Patients and method: In a personal series of 464 thyroid disorders undergoing surgery over two decades we recorded 51 patients (21.5%) aged over 65 years of which 11 (2.4%) having over 75 years. Demographic, clinical a...

Background: Chronic inflammatory processes of the thyroid represents an important proportion of the gland’s pathology but the majority of them must be treated by nonsurgical methods, thyroidectomy remaining circumstantially indicated.Patients and methods: In 14 cases (3%) from 464 operations for different thyroid lesions lesions we have encountered authentic inflammatory processes in nine cases of Hashimoto’s thyroiditis (two associated with pa...

Background: The optimal surgical technique in patients with refractory renal hyperparathyroidism (RHP) on hemodialysis for end stage renal disease is still a point of debates.The high percentage of recurrences after standard surgical procedures, i.e. subtotal parathyroidectomy (SPtx) and total parathyroidectomy with autotransplantation (TPtx+At) reactualised the practice of total parathyroidectomy (TPtx).Patients and methods: Forty...

Background: Renal hyperparathyroidism (RHPT) is a frequent complication of uremic patients on hemodialysis and despite various advances in medical therapy parathyroidectomy is necessary in a semnificative number of cases.Patients and methods: We reviewed our experience (first in Romania) regarding thirtyfour patients with RHPT operated on in our clinic between 1994 and 2007 evaluating the diagnosis methods, surgical indications, techniques and results to...