Endocrine Abstracts

Case presentation: A 40-year-old woman was admitted to the department of cardiology in our hospital due to iliofemoral deep vein thrombosis (DVT) in August 2010. It seemed that thrombosis was induced by the oral contraceptive (OC) which she had taken. Her serum level of von Willebrand factor was elevated. After the admission, the insertion of a temporary inferior venous cava (IVC) filter and thrombectomy were performed as well as starting of thrombolytic therapy and discontinu...

Objectives: Huge 9.0 magnitude quake and tsunami attacked eastern areas of Japan, on March 11th 2011. They claimed more than 20,000 lives and destroyed the nuclear power plants. Although the property damage was very little in Tokyo, about 250 miles apart from the epicenter, the people in capital faced a lot of hard situations. For example, unusual food supply, the lack of the daily necessities, the limitation of the electricity supply, and a fear of hundreds of aftershocks and...

Introduction: Brugade syndrome (BS) is a cardiac disorder characterized by typical electrocardiograph (ECG) alterations and is known to have a high risk of sudden cardiac death (SCD). Isolated ACTH deficiency (IAD) is often associated with fetal arrhythmia. Previous reports have suggested that certain endocrine diseases might cause Brugada-like ECG forms. We present a case of IAD with BS who died suddenly.Case presentation: Forty-one year-old man was ref...

A 44 year-old female patient visited our department for the treatment of diabetes. Her diabetes was pointed out 1 year before and was resistant to the treatment with oral hypoglycemic agents. From around the same time, she complained of repeated attacks consist of headache, palpitation, sweating and nausea. She had suffered from obsessive compulsive disorder for 20 years and her psychiatrist recognized that these attacks were caused by some psychological problems such as panic...

Introduction: Primary adrenocortical carcinoma (ACC) is a rare adrenal tumor and bilateral tumors are reported in 10% of total patient with ACC in Japan. We present a case of bilateral ACCs accompanied by severe muscle weakness.Case report: A 63-year-old male patient with bilateral adrenal masses was referred to our department for the examination and treatment of progressive muscle weakness and appetite loss lasting over 2 months. He was not able to stan...

Introduction: Agenesis of the dorsal pancreas, with the absence of the pancreatic body and tail, is a very rare developmental anomaly. To date, only 51 cases have been reported in the English literature. This anomaly can be a cause of diabetes mellitus.Case report: A 19-year-old Japanese male visited our department because of glucosuria that had been detected during a routine school health check. The patient had undergone cardiac surgery for atrial and v...

The availability of genome sequences from humans and multiple model organisms has facilitated the identification of many human plasma membrane receptor families and allowed the analysis of their phylogeny. We traced the evolution of known families of human plasma membrane receptors for inclusion in the Human Plasma Membrane Receptome database at http://receptome.stanford.edu (Science STKE. 2003). Using an evolutionary approach, we identified new polypeptide hormones and recept...