Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0011p343 | Diabetes, metabolism and cardiovascular | ECE2006

Obesity and expression of serotonin transporter (SERT) in human platelets

Marsili A , Santini F , Pelosini C , Betti L , Fabbrini L , Galli G , Ricco I , Baroni S , Italiani P , Fierabracci P , Giannaccini G , Pinchera A

Serotonergic transmission is involved in eating behaviour and body weight control. Comparison of SERT properties in blood platelets and serotonergic synaptosomes suggests that the human platelet can serve as an appropriate model for the transport, metabolism and release of serotonin by serotonergic neurons.Aim of this study was to evaluate SERT expression in platelets obtained from overweight or obese subjects (OB) as compared with normal weight healthy volunteers (C), and to ...
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ea0011p371 | Diabetes, metabolism and cardiovascular | ECE2006

Clinical, functional and polysomnographics parameters in severely obese patients

Giannetti M , Santini F , Di Giorgio M , Scartabelli G , Fierabracci P , Marsili A , Valeriano R , Ricco I , Galli G , Pucci A , Carpenè N , Vitti P , Palla A , Pinchera A

Obesity is a major cause of chronic hypoventilation and/or obstructive sleep apnea syndrome (OSAS). Aim of this study was to evaluate the prevalence of pulmonary dysfunction and the relationship between OSAS and several clinical, functional and polysomnographics parameters in severely obese patients. 101 subjects (68 females and 33 males) aged 49.2±13.2 years (mean±S.D.), with BMI 46.8±6.5 Kg/m2 were enrolled. Sleep quality and daytime ...
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ea0011p381 | Diabetes, metabolism and cardiovascular | ECE2006

Effects of bariatric surgery on preclinical myocardial alterations in severe obesity and the related role of insulin resistance

Pucci A , Santini F , Di Bello V , Marsili A , Fierabracci P , Di Cori A , Palagi C , Delle Donne MG , Giannetti M , Anselmino M , Vitti P , Balbarini A , Pinchera A

Obesity is a well established risk factor for congestive heart failure. The existence of an ‘obese cardiomyopathy’ has been hypothesized, as the complex combination of the effects of both hemodynamic and metabolic alterations. Aim of this study was to analyze the effect of bariatric surgery on the early myocardial alterations detected in a group of severe obese patients by high frame rate integrated backscatter (IBS). Twenty severely obese patients (5 males, 15 femal...
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ea0063p910 | Diabetes, Obesity and Metabolism 3 | ECE2019

Gestational Diabetes: what to say about body mass index and outcomes? The influence of prepregnancy body mass index on obstetric and neonatal outcomes of women with gestational diabetes

Ferreira Sara Esteves , Rosinha Patricia , Inacio Isabel , Alves Marcia , Azevedo Teresa , Dantas Rosa , Pedrosa Carla , Ferreira Marilia , Albuquerque Isabel , Fonseca Catarina , Jesus Andreia , Guimaraes Joana

Introduction: Due to the growing prevalence of obesity, more women are overweight in early pregnancy, leading to adverse neonatal and obstetric outcomes.Objective: To evaluate the influence of maternal prepregnancy body mass index (BMI) on blood glucose levels at diagnosis of gestational diabetes (GD), obstetric and neonatal outcomes.Methods: Retrospective observational study including women with GD and singleton pregnancy, with fo...
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ea0081p146 | Pituitary and Neuroendocrinology | ECE2022

Central Diabetes Insipidus, family report, molecular study, and its importance

Filipe Sa Luis , Sousa Rafaela , Villela Darine , Cavalcanti Thereza , Migliavacca Michele , Fontes Rosita , Guimaraes Marilia , Souza Micheline , Coelho Paula , Botelho Mariana , Nascimento Joao , Carvallo Mirna , Viveiros Pedro , Lourenco Jr Delmar , Naliato Erika , Violante Alice

Introduction: Central diabetes insipidus (CDI) occurs due to deficient secretion of arginine vasopressin (AVP) or antidiuretic hormone (ADH) by the posterior pituitary. It is a rare disease with an estimated prevalence of 1:25000. CDI can be acquired or congenital, secondary to malformation or genetics. Familial CDI (genetic inheritance) is mainly autosomal dominant. More than 80 mutations in the AVP gene have been described. In hereditary CDI, the age of onset is variable. Sy...
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ea0041ep793 | Obesity | ECE2016

Obstructive sleep apnoea syndrome – longitudinal outcomes and improvement predictors after bariatric surgery

Bettencourt-Silva Rita , Magalhaes Daniela , Souteiro Pedro , Sergio Neves Joao , Castro Oliveira Sofia , Manuel Costa Maria , Saavedra Ana , Bettencourt-Silva Marilia , Almeida Leonor , Drummond Marta , Queiros Joana , Varela Ana , Freitas Paula , Correia Flora , Carvalho Davide , AMTCO group Davide

Background: Bariatric surgery has been associated with a decrease in multiple obesity-related comorbidities including obstructive sleep apnoea syndrome (OSA). This study aims to access the OSA evolution in obese patients who underwent bariatric surgery.Methods: Retrospective longitudinal study of a population of obese patients who underwent bariatric surgery between January/2010 and July/2014 in our centre. Only patients who have undergone polysomnograph...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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