Endocrine Abstracts

Introduction: Narcolepsy is a rare sleep disorder characterized by excessive daytime sleepiness and REM-sleep abnormalities. Lateral hypothalamic hypocretin/orexin neurones are critical for normal wakefulness and energy expenditure, and the reduction of their activity has been linked with narcolepsy. Their activity is inhibited by extracellular glucose and the ‘satiety’ hormone leptin but stimulated by the ’hunger’ hormone ghrelin. Patients with narcolepsy ...

Background and Aims: The aim of our investigation was to evaluate the relationship between parameters of the metabolic syndroma (MSDR; NCEP/ATPIII Panel) in randomly selected diabetic patients (DM) with peripheral arterial occlusive disease (PAOD).Materials and Methods: diabetics, male 680 (49.7%), age (mean+SD) 52.6+14.4yrs. (16–84), were propectively examined using doppler examination and neuropathy disability scoring (NDS). PAOD was confirmed in ...

Acromegaly is associated with cardiovascular diseases. Accelerated atherosclerosis may have important role in that. The aim of this study was to examine the presence of dyslipidemia, glucose control imapairment, inflamation and hypertension as risk factors for the development of atherosclerosis in acromegalic patients.Study group included 28 patients with acromegaly without lesions of thyroid, adrenal and gonadal axis. The examination was performed befor...