Endocrine Abstracts

Background: Hyperinsulinemic hypoglycaemia refers to inappropriate secretion of insulin in the presence of low plasma glucose levels. One day old male infant 3.6kg, born to non-consanguineous parents referred for symptomatic hypoglycaemia. APGAR score was 8/10 and 9/10 at 1 and 5 minutes. There was no history of gestational diabetes mellitus in the mother. General physical examination was unremarkable. Glycemic monitoring revealed persistent hypoglycemia with low plasma glucos...

Background: ‘H’ syndrome is a rare autosomal recessive disorder characterised by hyperpigmentation, hypertrichosis, hepatosplenomegaly, hearing loss, hypogonadism, hyperglycaemia (insulin-dependent diabetes), hallux valgus and low height (short stature) and systemic inflammation. Caused by mutations in SLC29A3 gene located on chromosome 10q23 which encodes the human equilibrative nucleoside transporter 3 (hENT3). We report this case to highlight the rarity of the Syn...

Thyroid cancer if associated with bony metastases carries a poorer prognosis. Intensive multimodality treatment is usually necessary in management of these patients.Case: A 51-year-old female presented with hoarse voice in October 2005. Examination revealed a 3 cm left sided thyroid nodule and left vocal cord palsy. CT neck/thorax showed a multinodular goitre, with a dominant left nodule. FNA showed appearances suggestive of a follicular neoplasm. She un...

Aims: To calculate the sensitivity, specificity and positive predictive value of Parathyroid scintigraphy using Technetium-Sestamibi scan in the localization of parathyroid disease.Methods and material: This is a retrospective medical review of 161 patients who underwent the Parathyroid scintigraphy at our hospital in last six years. True positives were defined as patients with confirmed primary hyperparathyroidism (PHPT) on pathological examination. Tru...

Background: Insulinoma is an uncommon disease. The clinical profile of insulinomas among Indian patients is not well known.Aim of the study: To study the clinical characterstics, biochemical and radiological parameters,and treatment aspects of our adult patients with insulinomas.Methodology: We did a retrospective analysis of 18 patients with insulinoma treated from 1992 to 2004 in our institution. The data was analysed using a 11....

Aim: To analyse the clinical profile in patients with differentiated thyroid carcinoma.Materials & Methods: A retrospective analysis of case records of 232 patients who had under gone treatment for differentiated thyroid carcinoma from year 2000–2004 in Christian Medical College, Vellore was done and the intended data obtained using spss data.Results: A preoperative FNAC suggested thyroid neoplasm in 60%. Total thyroidecto...