Endocrine Abstracts

Objective: Pregnant women with autoimmune (subclinical) hypothyroidism have an increased risk of developing gestational diabetes mellitus (GDM). However, this association remains controversial in euthyroid women with thyroid autoimmunity (TAI). Therefore, the aim of the study was to determine the association between TAI and GDM in euthyroid women in a logistic regression analysis with adjustments for baseline/demographic parameters.Methods: Cross-section...

Context/Objective: Evidence on the impact of thyroid hormone treatment (LT4) on pregnancy outcomes in women with subclinical hypothyroidism (SCH) without TPOAb remains scarce. We assessed this relationship in a single centre in a real-world setting.Design, Setting, Participants: Cross-sectional study in 1460 women screened for TSH, free T4 and thyroid peroxidase antibodies (TPOAb) at median 13 (11-17) weeks of gestation, during the period 2013-2014. Excl...

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by variable combination of more than 20 types of endocrine and non-endocrine tumors: typically parathyroid glands, pancreatic islet cells and anterior pituitary gland are involved. We studied 20 patients (10M and 10F), affered to our Pituitary Unit in a period of 10 years. All patients had clinical diagnostic criteria suspected for MEN1 (presence of two endocrine tumors at least) and und...

In order to investigate the correlations between immunohistochemical picture with proliferative index (Ki-67), the clinical course and outcome of GH-secreting pituitary adenomas not cured by neurosurgery, we studied 41 consecutive acromegalic patients (M 12, F 29; aged 43±10.8 yr) previously undergone neurosurgical resection of adenoma. Two patients underwent neurosurgical intervention at least twice. Post-surgical follow-up ranged from 6 to 36 months and all patients rec...

Many patients affected by SARS-CoV-2 disease (COVID) have associated comorbidities (arterial hypertension, obesity, diabetes mellitus, thrombophilia) that are also tied to autonomous cortisol secretion. However, the prevalence of diseases of the adrenal glands in COVID patients is presently unknown. Since the visualization of the adrenal glands is almost always available in chest CT performed in patients with suspected or confirmed SARS-CoV-2 infection, the evaluation of adren...