Endocrine Abstracts

A 19 year old male was referred urgently due to a significantly raised Prolactin. He had seen his GP due to a cough, who then noted the patient had not progressed through puberty and organized further testing. On examination he had a BMI of 47. His height was 178 cm with a target of 184.5 cm (range 176-193). He had bilateral gynaecomastia with micropenis and pre-pubertal testes. He had never shaved and his voice was high-pitched. He did not report anosmia. Visual fields were n...

Background: Non-type 1 diabetes mellitus (T1DM) and T2DM accounts for up to 4% of cases of paediatric diabetes. The most common form is maturity-onset diabetes of the young, however rarer forms exist.This case highlights a number of important points to be considered when investigating patients with ketoacidosis that is not typical of T1DM. An understanding of the ketogenic pathway and knowledge of differential diagnoses for ketoacidosis and their appropr...

Background: Peutz Jegher’s syndrome is a rare condition with substantial cancer risk. Testicular cancer risk is 9%, the commonest being pre-pubertal large cell Sertoli cell tumour (LCST) which usually presents with bilateral gynecomastia. Here we present a case of Peutz Jegher’s syndrome with LCST who presented with unilateral gynecomastia.Case: A 5-year-old boy was referred to our endocrine service with unilateral gynecomastia. He had right si...

Introduction: It is too much easier and cheaper to combat obesity, than in the future to treat diabetes mellitus and its complications.Methods: We used an online system for patient education based on the video lessons, full of humor, pictures, and cartoons to convey the necessary information on good nutrition, necessary to do exercises and the need for exposure to the sun to our patients.Results: Watching the short movies, the pati...

Introduction: To maintain an average HbA1c of less than 48 mmol/mol requires good diabetes control throughout the year. School holidays take on average 13 weeks (25%) of the year in the UK, therefore good control in holidays as well as term-time is paramount. Little work has been done in this area but it has been suggested diabetes control may be worse during holidays. This study aimed to retrospectively compare diabetes control between term time and the school holidays.<p...

Introduction: The NPDA presents data on management, treatment, and complications for all diabetes units in the country. This acts as a driver for quality improvement and aims to improve standards of diabetes care. The 2019 report identified a relatively high proportion of children with hypertension locally. An audit aimed to identify the proportion of local diabetes patients with ‘hypertension’ or ‘pre-hypertension’, and their clinical identification. The s...

Introduction: Type 2 diabetes mellitus (T2DM) is associated with urological and endocrine complications, including erectile dysfunction (ED) and hypogonadism.Aim: REVITALISE was conducted to assess men with/without T2DM at risk of ED and/or hypogonadism, and highlight gaps in current clinical management.Methods: Data were collected from 13 UK primary care practices on incidence of ED, hypogonadism (defined as serum total testostero...

Introduction: Paediatric hypoglycaemia is a relatively common medical emergency. In order to allow identification of the underlying cause, investigations need to be performed urgently prior to treatment being given. If done correctly this can save the need for future investigations. A ‘hyposcreen’ costs ~£450 so careful consideration is needed to ensure correct patient selection, as inadequate investigations have further cost and patient safety implications....

Introduction: In the majority of patients presenting to A&E with hypoglycaemia it is secondary to infection or stress and individuals exhibit a ketogenic response. A minority who first present with hypoglycaemia may have endocrine or metabolic disorders. For this reason a full ‘hypoglycaemia screen’ is undertaken. It is recommended by metbionet that before glucose administration, the following are measured: intermediary metabolites (glucose, b-OHB, free fatty aci...

Introduction: The National Paediatric Diabetes Audit (NPDA) provides a benchmark of performance for paediatric diabetic services across the UK. Whether intentional or not, a league table is created comparing units based on their mean HbA1c. Although the coordinators suggest submitting the patients’ most recent HbA1c, this may not necessarily be a universally adopted phenomenon. We examined the effect of selecting patient’s best, yearly average, and latest HbA1c on ou...