Endocrine Abstracts

In the United States of America, among adults, the prevalence of type 2 diabetes has increased nearly 5 fold over the last half century. During this unfolding epidemic among adults, type 2 diabetes has now emerged among children. Primarily thought to be a disease of adults, type 2 diabetes was first described among Pima Indian children in the late 1970s. Since then, a number of clinic-base case series have clearly described type 2 diabetes in children of all racial and ethnic ...

An estimated 100 million people worldwide currently suffer from type 2 diabetes mellitus (T2DM). The incidence of T2DM is steadily escalating throughout the world in people from a wide range of ethnic groups and all social and economic levels. Parallel with the global epidemic of T2DM in adults, an 'emerging epidemic' of T2DM has been observed in youth over the last decade. Research and clinical experience in adults have established that insulin resistance is a major risk fact...

Childhood onset Type 2 diabetes mellitus is appearing in Asia. Sadly, the risk factors appear to be obesity, a sedentary lifestyle, and a family history of type 2 diabetes mellitus or gestational diabetes and IUGR. Comorbidities include abnormal lipid profiles, steatohepatitis, hypertension for age and obstructive sleep apnoeaModalities of treatment include diet, exercise, insulin, metformin, and sulphonylureas and more recently, the use of insulin sens...