Searchable abstracts of presentations at key conferences in endocrinology
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Volume 3
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BES2002
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21st Joint Meeting of the British Endocrine Societies
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0043 WCTD2016
0042 Androgens2016
0041 ECE2016
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0036 BSPED2014
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Summary
Abstracts
Contents
Plenary Lectures
Clinical Endocrinology Trust Lecture
The apple of my eye
ea0003s1
Clinical Endocrinology Trust Lecture
ea0003s1biog
Society for Endocrinology Transatlantic Medal Lecture
Mechanisms of preterm birth, and influences on disease in later life
ea0003s2
Society for Endocrinology Transatlantic Medal Lecture
ea0003s2biog
Clinical Endocrinology Trust Visiting Professor Lecture
The neuroendocrinology of Stress
ea0003s3
Clinical Endocrinology Trust Visiting Professor Lecture
ea0003s3biog
British Thyroid Association - Pitt-Rivers Lecture
Molecular genetics of congential hypothyroidism
ea0003s4
British Thyroid Association - Pitt-Rivers Lecture
ea0003s4biog
Society for Endocrinology Dale Medal Lecture
Darwin, De Graaf and selection of the ovulatory follicle(s)
ea0003s5
Society for Endocrinology Dale Medal Lecture
ea0003s5biog
Symposia
Hormonal Control of Female Reproduction
Transgenic models to study ovarian folliculogenesis and oogenesis
ea0003s6
The generation of the preovulatory LH surge
ea0003s7
Role of cofactors for nuclear receptors in reproduction
ea0003s8
Role of COX-2 in implantation
ea0003s9
Recent Advances in Biological Rhythms
Molecular mechanisms of the circadian clockwork
ea0003s10
Photoperiodic regulation of the neuroendocrine system
ea0003s11
Human physiological implications of biological timing
ea0003s12
Endocrine and other biological rhythms in man
ea0003s13
Vascular Risk in Diabetes - Genetic and Environmental Interactions
Diabetes and vascular risk
ea0003s14
Genetic basis of type 2 diabetes
ea0003s15
From QTL locus to insulin resistance gene
ea0003s16
Lifestyle and environmental interactions in type 2 diabetes
ea0003s17
Differentiated Thyroid Cancer
Initiating oncogenic events in thyroid follicular cells: Impact on chromosomal instability and disease progression
ea0003s18
Improving the utility of fine needle aspiration biopsy of thyroid tumours
ea0003s19
Differentiated Thyroid Cancer (DTC): Treatment Outcomes
ea0003s20
UK thyroid cancer guidelines
ea0003s21
Metalloproteinases and Their Inhibitors: Regulators of Endocrine Activity
The biology of matrix metalloproteinases and their inhibitors
ea0003s22
Matrix metalloproteinases, cytokines and bone/cartilage remodelling
ea0003s23
Metalloproteinases and the modulation of growth hormone signalling
ea0003s24
The functional role of matrix-degrading proteinases and their inhibitors in the female reproduction system
ea0003s25
Cell Based Therapies for Treating Neuroendocrine Disease
Embryonic stem cells: Their potential for therapeutics
ea0003s26
Human neural stem cells: A therapeutic modality for neurodegenerative disease
ea0003s27
Engineering cells to treat diabetes
ea0003s28
Repairing and protecting neurones, a dual goal for cell based therapy to the brain
ea0003s29
Parturition and Fetal Stress - Hormonal Strategies for Ensuring Life After Birth
New insights into lung maturation - the role of interleukin-1
ea0003s30
Parturition and fetal stress: hormonal strategies for ensuring life after birth
ea0003s31
Thyroid hormone in the fetal brain
ea0003s32
The prolactin receptor and pregnancy
ea0003s33
Clinical Management Workshops
Insulin Resistance and Type 2 Diabetes in Adolescents and Young Adults
Epidemiology of type 2 diabetes in childhood and adolescents in North America: Possible lessons for the UK
ea0003s34
Pathophysiology of type 2 diabetes in adolescents and young adults
ea0003s35
Management of adolescents and young adults with insulin resistance
ea0003s36
New Treatments for Osteoporosis
Prospects for new treatment approaches in osteoporosis
ea0003s37
Parathyroid hormone for osteoporosis treatment
ea0003s38
Statins for the prevention of postmenopausal osteoporosis
ea0003s39
Unconventional Uses of Thyroid Hormones
T3/T4 combination therapy
ea0003s40
Unconventional uses of thyroid hormones: Psychiatric indications in mood disorder
ea0003s41
Cardiac indications
ea0003s42
Why, Why Not and When to Irradiate the Pituitary
Radiotherapy for pituitary disease
ea0003s43
Radiobiology, conventional fractionated pituitary radiotherapy and stereotactic LINAC radiotherapy
ea0003s44
Gamma-knife radiotherapy of pituitary tumours
ea0003s45
Oral Communications
Genetics: New Insights into Endocrine Disease
All in the family: Site and gender specificity of the genetic control of bone mineral density
ea0003oc1
GATA3 mutations in the hypoparathyroidism, deafness and renal dysplasia (HDR) syndrome
ea0003oc2
A molecular deletional-insertion involving chromosomes Xq27 and 2p25 causes X-linked recessive hypoparathyroidism
ea0003oc3
Analysis of novel mutations in the HSD11B2 gene: Implications for AME and possibly IUGR
ea0003oc4
Identification of differentially expressed genes in rat chromosome 2 congenic strains
ea0003oc5
Y chromosome consomic strains and metabolic syndrome in the stroke prone spontaneously hypertensive rat
ea0003oc6
The vitamin D receptor gene is associated with susceptibility to development of Graves' disease in the UK
ea0003oc7
Identification and characterization of a novel missense mutation in the growth hormone gene in a child with short stature
ea0003oc8
Endocrine Neoplasia
Breast cancer cells express the vitamin D activating enzyme 1alpha-hydroxylase
ea0003oc9
2-methoxyestradiol sulphamatas induce G2-M arrest and apoptosis in ER-VE MDA-MB-231 breast cancer cells
ea0003oc10
CYP24 action: An intrinsic mechanism of resistance in breast and prostate cancer cells
ea0003oc11
Ghrelin inhibits proliferation of breast cell lines acting via the growth hormone secretagogue receptor (GHS-R)
ea0003oc12
Disruption of the SH3 domain of pituitary tumor transforming gene (PTTG) reveals distinct mechanisms of FGF-induction and cell transformation
ea0003oc13
Expression and function of vascular endothelial growth factor (VEGF) and its receptor KDR in pituitary tumours
ea0003oc14
Regional gene expression in the colon of patients with and without acromegaly
ea0003oc15
BPDZ-154 is a potent activator of ATP-sensitive potassium channels in pancreatic beta-cells
ea0003oc16
Growth Regulation
The identification of cryptic gene sequences that encode putative ligands: The example of POP1
ea0003oc17
Overexpression of insulin-like growth factor binding protein-5 (IGFBP-5) induces severe growth retardation in transgenic mice
ea0003oc18
Thyroid hormone activates fibroblast growth factor receptor-1 in bone
ea0003oc19
Advanced bone formation in mice with resistance to thyroid hormone due to a targeted mutation in the thyroid hormone receptor beta gene
ea0003oc20
Decidual matrix metalloproteases MMP-3 and MMP-9 proteolyse insulin-like growth factor binding protein-1
ea0003oc21
The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ZD1839 ('Iressa') inhibits growth of human pituitary cells expressing a mutated form of the EGFR
ea0003oc22
Follicle-stimulating hormone and transforming growth factor beta superfamily members regulate granulosa cell connective tissue growth factor (CTGF) gene expression in vitro and in vivo
ea0003oc23
Abnormalities of folliculogenesis in polycystic ovaries start at the primordial stage
ea0003oc24
Metabolism
Programming of adult adipose tissue metabolism by prenatal glucocorticoids in the rat
ea0003oc25
Impact of thiazolidinediones on cardiovascular disease risk factors
ea0003oc26
A digenic basis for severe insulin resistance in a large UK kindred - cosegregation of mutations in PPAR gamma and PPP1R3
ea0003oc27
Rosiglitazone inhibits insulin-mediated rise in angiotensinogen expression and angiotensin II secretion in human subcutaneous adipocytes
ea0003oc28
Deleterious effect of non-esterified free fatty acids (NEFAs) on resistance artery endothelial function
ea0003oc29
Increased muscle oxidation of dietary lipid contributes to oestrogen-induced improvements in postprandial lipid metabolism
ea0003oc30
An interaction between ghrelin and a species of high-density lipoprotein
ea0003oc31
Regulation of leptin receptor cleavage
ea0003oc32
Hormone Action
The role of the PPAR gamma in thyroid eye disease: Possible contra-indication for thiazolidenedione therapy
ea0003oc33
Iodothyronine deiodinase expression in thyroid responsive fetal tissues
ea0003oc34
Modification of calcium sensing receptor expression modulates 25-hydroxyvitamin D3-1alpha-hydroxylase activity in a human proximal tubule cell line
ea0003oc35
Increasing fracture risk with age: Possible role of local corticosteroid generation
ea0003oc36
Demonstration of progesterone receptor mediated gonadotrophin suppression in men
ea0003oc37
Autocrine generation of androgens within adipose tissue: Implications for polycystic ovarian syndrome (PCOS)
ea0003oc38
DHEA, a selective glucocorticoid receptor antagonist, studies in human lymphoblasts and hepatocytes
ea0003oc39
RU486, the glucocorticoid receptor (GR) antagonist, recruits NCoR, but not SRC-1: Explaining type II antagonism
ea0003oc40
Neuroendocrinology
11beta-hydroxysteroid dehydrogenase type 1 (11beta HSD1) is expressed in human brain: inhibition with carbenoxolone improves cognitive function in healthy elderly men
ea0003oc41
A possible role for the melanocortin 3 receptor in the control of the hypothalamo-pituitary gonadal axis
ea0003oc42
CGRP-alpha inhibits food intake via the paraventricular nucleus (PVN) of the hypothalamus partly through the CGRP-type 1 receptor
ea0003oc43
MSH precursor peptides in rat cerebrospinal fluid: Evidence that pro-opiomelanocortin (POMC) processing is regulated with respect to energy balance
ea0003oc44
Evidence for a role of the ATP-binding cassette transporter - A1 (ABC-A1) in the externalisation of annexin I from folliculostellate cells
ea0003oc45
Chronic CNS administration of Agouti related protein (Agrp) reduces energy expenditure
ea0003oc46
A2B adenosine receptors mediate the adenosine-induced increase in cell growth and IL-6 expression in pituitary folliculostellate cells
ea0003oc47
Hypothalamic actions of Neuromedin U
ea0003oc48
Poster Presentations
Novartis Award Posters
A molecular deletional-insertion involving chromosomes Xq27 and 2p25 causes X-linked recessive hypoparathyroidism
ea0003np1
11beta-Hydroxysteroid dehydrogenase type 1 (11betaHSD1) is expressed in human brain; inhibition with carbenoxolone improves cognitive function in healthy elderly men
ea0003np2
Bone
Bone mineral density in children with insulin dependent diabetes mellitus (IDDM)
ea0003p1
Bone mineral density of asthmatic children after long term treatment with inhaled corticosteroids
ea0003p2
Investigation into the plasticity of adult human bone marrow adipocytes
ea0003p3
Is bone mineral density in women with type 2 diabetes different from nondiabetic women?
ea0003p4
Changes in parathyroid hormone sensitivity and rhythmicity and its effects on bone metabolism following growth hormone replacement in adult growth hormone deficient patients
ea0003p5
Evaluation of vitamin-D deficiency and other bone biochemical factors in urban population of Tehran - winter 2001
ea0003p6
Bone turnover markers after a single intravenous injection of growth hormone in adults with growth hormone deficiency
ea0003p7
Availability of a reliable marker of bone resorption in serum, C-terminal cross-linking telopeptide of type I collagen, for evaluation of metabolic bone disease
ea0003p8
Development of bone remodelling balance and turnover indices in patients with metabolic bone disease
ea0003p9
A comparative study of raloxifen and estrogen on bone strength and cholesterol levels in ovariectomized rats
ea0003p10
Effect of rosiglitazone on bone strength in osteoporotic rats
ea0003p11
Clinical Case Reports
The perils of low dose locally delivered steroids
ea0003p12
Isolated growth hormone deficiency and BPES
ea0003p13
Pituitary mass and hypopituitarism with Wegeners granulomatosis
ea0003p14
Hyperparathyroidism and polycythaemia
ea0003p15
Type 1 diabetes in the elderly
ea0003p16
Management of thyrotoxicosis in a non-compliant pregnant woman
ea0003p17
Lack of cortisol response using the glucagon stimulation test in diabetic autonomic neuropathy
ea0003p18
'Brittle Addison's disease' but not 'Brittle diabetes' in a young woman with Addison's disease and type 1 diabetes mellitus
ea0003p19
A rare cause of intrasellar mass: Cholesterol granuloma
ea0003p20
Mitochondrial inheritance of maternal, familial short stature with diabetes mellitus
ea0003p21
Prolactin elevation to 16,630 mU/l in a case of a large non-functioning pituitary adenoma
ea0003p22
Glucocorticoid remediable aldosteronism. A Northern Ireland experience
ea0003p23
Acute polyarticular synovitis complicating Grave's disease
ea0003p24
Congenital adrenal hyperplasia: A tale of two enzymes
ea0003p25
A new management for congenital adrenal hyperplasia?
ea0003p26
A case of pseudohypoparathyroidism with diagnostic dilemmas
ea0003p27
Cushing's syndrome of indeterminate origin. Sucessful treatment of a liver abscess after therapy with a block and replacement medical regimen
ea0003p28
Self-hypophysectomy - and return to normal
ea0003p29
Acute presentation of a ruptured craniopharyngioma
ea0003p30
What is the natural history of scalp hairloss in association with the use of somatostatin analogues in the treatment of acromegaly?
ea0003p31
Fish oil and antacids: A cautionary tale
ea0003p32
Primary hyperaldosteronism in association with primary hyperparathyroidism and prolactinoma - a case report
ea0003p33
A case of Gitelman's syndrome
ea0003p34
Iatrogenic Acromegaly
ea0003p35
Efficacy and safety of high dose testosterone therapy in partial androgen insensitivity
ea0003p36
Xanthoma Disseminatum: A rare cause of hypopituitarism
ea0003p37
Sustained improvement in vision in a recurrent growth hormone secreting macroadenoma during treatment with octreotide in the absence of marked tumour shrinkage. A reason for cautious optimism ?
ea0003p38
Hyperprolactinaemia in a patient taking the herbal remedy Agnus Castus
ea0003p39
Differentiated thyroid carcinoma with large bony metastases - what is the best approach?
ea0003p40
An unusual presentation of sarcoidosis
ea0003p41
A spontaneously resolving mediastinal parathyroid adenoma with no previous Tc-99m pertechnetate uptake
ea0003p42
A patient with Turner's syndrome, type 2 diabetes and primary biliary cirrhosis
ea0003p43
A case of polyuria, thirst and weight loss
ea0003p44
Growth hormone deficiency in salt-losing congenital adrenal hyperplasia
ea0003p45
Steroid responsiveness in a case of Riedel's thyroiditis and retroperitoneal fibrosis
ea0003p46
Thromboembolism in patients with Cushing's disease - a retrospective case review
ea0003p47
Multidisciplinary management of Cushing's syndrome due to a malignant thymic carcinoid tumour
ea0003p48
Li-Fraumeni syndrome with adrenocortical tumours producing oestrogens in the father and testosterone in his 18-month-old daughter
ea0003p49
Cushing's disease and nasal obstruction from a large biochemically 'silent' corticotroph adenoma
ea0003p50
Cushing's syndrome presenting with weight loss and type II diabetes mellitus
ea0003p51
Extremely long effects of vitamin D therapy: A near-fatal complication of thyroid surgery
ea0003p52
Severe thyroid eye disease associated with stable primary hypothyroidism
ea0003p53
Apparent mineralocorticoid excess caused by Barnips cough tablets
ea0003p54
Bilateral adrenal histoplasmosis
ea0003p55
Cranial diabetes insipidus and possible prolactinoma-an interesting case
ea0003p56
The use of the domperidone test in differentiating macroprolactinaemia from true hyperprolactinaemia
ea0003p57
A case report of hungry bone syndrome in the course of Graves disease
ea0003p58
Anaplastic carcinoma of the thyroid presenting with hyperthyroidism
ea0003p59
A case of Addison's disease caused by the antiphospholipid syndrome
ea0003p60
Acute adrenal insufficiency and encephalomeningitis with cerebral haemorrhage: A case of secondary lupus anticoagulant syndrome?
ea0003p61
Pituitary carcinoma - a pain in the head and a pain in the neck
ea0003p62
A case of false immunoassay results due to assay interference
ea0003p63
Prolactinoma and macroprolactin
ea0003p64
Is the Endocrine nurse too accessible?
ea0003p65
Ghanaian influenza
ea0003p66
Seizures as first manifestation of catch 22 syndrome in adulthood
ea0003p67
An androgen-secreting tumour presenting with resistant hypertension and an 'incidentaloma'
ea0003p68
A near fatal case of haematuria
ea0003p69
An unusual case of secondary amenorrhea
ea0003p70
A diagnostic trilemma of primary adrenal failure, sepsis and HITTS
ea0003p71
Cytokines and Growth Factors
Studying of e-selectin in patients with diabetes type 1 amp microangiopathy
ea0003p72
The universal expression of ghrelin in normal and malignant breast tissue and its association with tumourigenic genes
ea0003p73
Antiangiogenic effect of lanreotide on GH-secreting pituitary adenomas
ea0003p74
Ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon: Importance of P-selectin, CXC chemokines
ea0003p75
Expression of the membrane interleukin-6 receptor (mIL6R) but absence of shedding of soluble IL6R (sIL6R) in human pituitary tumour cells
ea0003p76
Inhibitory effects of interleukin1-alpha, interleukin-6 and leptin on growth of HP75 human pituitary tumour cells
ea0003p77
Leptin increases expression of CD11b on human neutrophils
ea0003p78
Adrenomedullin stimulation of cytokines and growth factor release in endothelial cells and skin fibroblasts: A possible role in wound healing
ea0003p79
Growth hormone treatment does not decrease homocysteine levels
ea0003p80
Bacterial lipopolysaccharide directly stimulates cortisol secretion by human adrenal cells
ea0003p81
IGFBP-5 regulates IGF-I mediated signaling and survival in the mouse mammary gland
ea0003p82
Diabetes & Metabolism
Effects of growth hormone replacement (GHR) on VLDL and LDL APOB100 kinetics in growth hormone deficient (GHD) subjects
ea0003p83
The effect of growth hormone replacement (GHR) on lipoprotein composition in growth hormone deficient (GHD) hypopituitary adults
ea0003p84
Demonstration of diurnal variation of plasma glycated insulin in type 2 diabetes
ea0003p85
Increased red cell folate subsequent to folic acid supplementation in type II diabetes results in a reduction in microalbumin excretion but an increased atherogenic lipid profile
ea0003p86
Changes in anthropometric, metabolic and insulin resistance indices among offspring of caribbean patients with type 2 diabetes mellitus
ea0003p87
Insulin secretion and metabolic control in Caribbean type 2 diabetic patients commonly treated with sulphonylurea drugs
ea0003p88
Abnormalities of vascular function and fibrinolysis in young women with polycystic ovary syndrome
ea0003p89
Insulin resistance and metabolic syndrome in obese children
ea0003p90
Thioland and steriod levels in polycystic ovary syndrome
ea0003p91
Acanthosis nigricans: A valid clinical marker of insulin resistance in obesity
ea0003p92
Effects of ACE inhibitors on myocardial infarction, cerebrovascular death, stroke, diabetic nephropathy and insulin sensitivity in patients with diabetes mellitus type 2
ea0003p93
Screening strategy and cost analysis of gestational diabetes mellitus in Iranian pregnant women
ea0003p94
Incidence of hypertension in patients with gestational diabetes mellitus and non diabetic pregnant women
ea0003p95
Effectiveness of a weight management programme in a hospital staff setting
ea0003p96
The expression of resistin mRNA in human adipose tissue
ea0003p97
Expression of adiponectin mRNA in human adipose tissue depots in non-diabetic and diabetic patients
ea0003p98
Expression of purinergic receptors in human insulin-secreting cells in health and disease
ea0003p99
A novel gender dimorphism in the response of the gonadal axis to critical illness
ea0003p100
Weight gain is not inevitable in the management of type 2 diabetes mellitus
ea0003p101
Comparison of effect of insulin in hypothyroidism and after the thyroid hormone therapy
ea0003p102
The utility of the HOMA model for identifying women with polycystic ovarian syndrome (PCOS) who are insulin resistant
ea0003p103
Paradoxical variability of SHBG and insulin resistance in PCOS patients and controls
ea0003p104
Islet amyloid polypeptide (IAPP) accumulates in lysosomes of human beta-cells by crinophagy but does not form fibrils
ea0003p105
Audit on lipid management in diabetes
ea0003p106
Single nucleotide polymorphisms in the ghrelin gene in tall obese children
ea0003p107
Paediatric diabetes survey shows type 2 diabetes prevalence 0.4%, distinct from type 1, and associated with overweight, puberty, female sex and ethnic minority status
ea0003p108
ACTH stimulates insulin secretion by MIN6 mouse insulinoma cells
ea0003p109
Intensive insulin therapy in diabetic pregnancy
ea0003p110
Counterregulatory hormone responses to hypoglycaemia in type 2 diabetes mellitus - comparison of metformin and sulphonylurea treated subjects
ea0003p111
Complication in acute myocardial infarction and admission hyperglycaemia
ea0003p112
Serum lipoprotein (a) and other lipid parameters in patients with liver cirrhosis and chronic active hepatitis
ea0003p113
Lectin binding of serum hCG in pregnancy and type 1 diabetes
ea0003p114
Atorvastatin decreases LDL oxidation in glucocorticoid excess state
ea0003p115
A pilot study of metformin for the treatment of hirsutism in patients without diabetes
ea0003p116
Ultrasound features of polycystic ovaries (PCO) and metabolic syndrome X
ea0003p117
Endocrine Tumours and Neoplasia
Outcome of transphenoidal surgery by one surgeon for acute acromegaly
ea0003p118
Identification of novel epigenetically silenced sequences in pituitary tumours
ea0003p119
Expression of the F-box protein Skp-2 in normal and tumorous human pituitary
ea0003p120
High resolution allelotyping of adenomas identifies novel regions of genetic loss
ea0003p121
Cushing's syndrome due to apparently autonomous adrenal hyperplasia in a patient with multiple endocrine neoplasia type I
ea0003p122
An evalution of endocrine assessment of patients with pituitary tumours prior to tertiary referral
ea0003p123
Hereditary multiple exostosis due to an acceptor splice site mutation in the EXT1 gene
ea0003p124
Approaches to evaluating the role of vitamin D receptor polymorphisms in breast and prostatic carcinoma
ea0003p125
Treatment options for refractory hypercalcaemia in a patient with PTHrP-secreting neuroendocrine tumour and primary hyperparathyroidism
ea0003p126
Multiple endocrine neoplasia type 1 (MEN-1) with two different pancreatic tumours
ea0003p127
Cigarette smoking exposure, serum insulin-like growth factors, and cancer risk: A population-based study
ea0003p128
Hypercalcaemia associated with clear cell carcinoma of the ovary
ea0003p129
pound31,474 saved with shared care
ea0003p130
The pathogenesis of pancreatic beta-cell adenoma does not involve defects in ATP-sensitive potassium channels
ea0003p131
Do symptoms and signs of acromegaly correlate with GH during medical treatment?
ea0003p132
Alterations in expression levels of ER subtypes and their coregulators in endocrine resistant breast cancer
ea0003p133
A role for co-regulators in estrogen receptor function
ea0003p134
Experience with cabergoline therapy in 34 patients with acromegaly
ea0003p135
Expression of somatostatin receptor subtypes 1, 2, 3, and 5 in the hyperplastic and neoplastic endometrium
ea0003p136
Do non-functioning pituitary adenomas with positive immunoreactivity for ACTH behave more aggressively than other non-functioning adenomas?
ea0003p137
Chronic lymphoedema improved by the diagnosis and treatment of underlying acromegaly
ea0003p138
The destruction box of pituitary tumor transforming gene (PTTG) mediates cell transformation
ea0003p139
Growth hormone receptor and type 1 IGF receptor in human somatotroph tumours
ea0003p140
Hunting for oncogenes in pituitary adenomas - a cautionary tale of new technology
ea0003p141
Diagnostic accuracy of ultrasound in preoperative assessment of primary hyperparathyroidism
ea0003p142
Choice of calcitonin assay
ea0003p143
The incidence of colorectal neoplasia in acromegaly
ea0003p144
Clinical and biochemical findings in paragangliomas
ea0003p145
Inhibition of 11beta-HSD2 has an anti-proliferative effect on pituitary tumour cells
ea0003p146
Reference ranges for urinary metadrenalines in patient populations
ea0003p147
Primary medical management of macroprolactinomas with cabergoline(CAB)
ea0003p148
Routine calcitonin measurement in management of thyroid nodules: A decision analysis approach
ea0003p149
Patterns and mechanisms of hypercortisolism in association with phaeochromocytoma
ea0003p150
Ghrelin, but not GHRP-6 or hexarelin increases proliferation of colonic epithelium via effects on c-myc mRNA
ea0003p151
Genetics
No association of a 3' UTR polymorphism of the interleukin-12 P40 (IL12B) gene with Grave's disease in a UK population
ea0003p152
Lack of association of the insulin gene region with Grave's disease in the UK
ea0003p153
The angiotensin II response to an acute exercise stimulus and the angiotensin converting enzyme (ACE) genotype
ea0003p154
A nonsense mutation in exon two of the DNASE1 gene is not present in UK subjects with SLE and autoimmune thyroid disease
ea0003p155
Seven novel mutations in the androgen receptor gene associated with complete androgen insensitivity syndrome
ea0003p156
Compound heterozygous AIRE-1 mutations in autoimmune polyendocrinopathy type 1
ea0003p157
Lack of association between polymorphic markers within 11b-hydroxysteroid dehydrogenase type 1 gene (HSD11B1) and obesity
ea0003p158
Single nucleotide polymorphisms of the beta2-adrenergic receptor (ADRB2) gene and hypertension
ea0003p159
Independent Y chromosome markers associated with blood pressure and testosterone levels
ea0003p160
Growth and Development
Increased heights and weights of Isfahani male children and adolescents in Iran
ea0003p161
Androgen receptors are expressed in the developing antler tip and velvet skin of the red deer (Cervus elaphus )
ea0003p162
Gender variation in leptin circadian rhythm and pulsatility in adult growth hormone deficiency; effects of growth hormone replacement
ea0003p163
Monitoring insulin-like growth factor-I and IGF binding protein-3 in children and adolescents on GH treatment using filter paper blood spots
ea0003p164
Serum Ghrelin concentrations in healthy children and adolescents
ea0003p165
BMI corresponds to oestradiol levels and delayed puberty in boys
ea0003p166
An audit of paediatric to adult transition of childhood onset growth hormone deficiency
ea0003p167
Factors affecting insulin-like growth factor I response to growth hormone (GH) treatment in GH-deficient adults
ea0003p168
Familial combined pituitary hormone deficiency by PROP1 gene mutation, in a Portuguese family
ea0003p169
A survey of the investigation of short stature in Wales
ea0003p170
Accelerated aortic root dilatation in Turner syndrome
ea0003p171
Cellular proliferation in the adrenal cortex in vitro
ea0003p172
Developmental regulation of the mt1 melatonin receptor gene in the rat pituitary gland
ea0003p173
Growth hormone therapy decreases LDL oxidation in oestrogen deficiency
ea0003p174
Abnormal collagen morphology and decreased bone strength in growth hormone deficient rats
ea0003p175
Growth hormone replacement: Patients' views
ea0003p176
Neuroendocrinology
Growth hormone deficient patients over 60 years require a low dose of GH and short titration phase to achieve normal serum IGF-I levels
ea0003p177
A relationship between interleukin-1 and interleukin-6 secretion by human pituitary adenomas in culture
ea0003p178
Time dependency of somatotroph dysfunction following radiation damage of the hypothalamic-pituitary axis
ea0003p179
Ghrelin is acutely regulated by insulin but not glucose
ea0003p180
Gender differences in the relationship between leptin and the autonomic nervous system
ea0003p181
Magnetic resonance perfusion enables assessment of blood supply to pituitary gland
ea0003p182
Long term treatment of adult growth hormone deficiency does not normalise quality of life compared to control subjects: A need for a different strategy?
ea0003p183
Expression and purification of histidine-tagged anosmin-1 by drosophila S2 cells and Ni-NTA agarose chromatography
ea0003p184
Cardiac sympathovagal balance correlates positively with age in growth hormone deficient (GHD) patients
ea0003p185
The pattern of green fluorescent protein (GFP) expression following intrahypothalamic injection of adeno-associated virus-GFP
ea0003p186
The effect of serotonin on the GH, T3, T4, milk production and composition
ea0003p187
Diet-induced obesity in the Sprague-Dawley (SD) rat
ea0003p188
The correlation between serum insulin-like growth factor 1 levels and creatinine clearance in adults with growth hormone deficiency
ea0003p189
Functional neurosecretory GnRH deficiency in a man with adult onset hypogonadotrophic hypogonadism: an unrecognised entity?
ea0003p190
Precipitating factors and surgical outcome in pituitary apoplexy
ea0003p191
Single centre audit of surgical outcome in Cushing's disease
ea0003p192
Leptin and leptin receptors are developmentally regulated in rat pituitary
ea0003p193
Influence of age on the vulnerability of the hypothalamic-pituitary axis to radiation damage
ea0003p194
Weight gain and obesity in patients with hypothalamic damage
ea0003p195
Urinary catecholamines and catecholamine-metabolites in the immediate post-operative period following coronary revascularization surgery
ea0003p196
The effect of bombesin on the Gh, T3, T4 and milk production and compositions
ea0003p197
Functional complement C3a receptors in the rat pituitary gland
ea0003p198
Serum IGF-I levels and correlation with functional activity in the elderly
ea0003p199
Disease activity in acromegaly may be assessed four weeks after discontinuation of pegvisomant
ea0003p200
Outcome of treatment for Cushing's disease in Birmingham; the experience of a single surgeon
ea0003p201
Beta-adrenergic input exerts both acute and chronic effects on steroid production in H295R human adrenocortical cells
ea0003p202
Neuropeptides and adrenocortical proliferation in vitro
ea0003p203
Growth hormone (GH) deficiency in adults treated for acute lymphoblastic leukaemia (ALL) in childhood
ea0003p204
Outcomes in the management of pituitary apoplexy; a conservative approach may be prudent
ea0003p205
Prolactin releasing peptide does not have a significant role in the control of growth hormone secretion either in vitro or in vivo in freely moving male rats
ea0003p206
Measures of cardiovascular parameters in patients with acromegaly switched from SC octreotide to Sandostatin-LAR
ea0003p207
Reproduction
Is the antidiuretic effect of recombinant prolactin mediated by changes in the glomerular filtration rate?
ea0003p208
Cardiovascular risk profiles in women with polycystic ovarian syndrome (PCOS)
ea0003p209
Weight change and androgen levels during contraceptive treatment of women affected by polycystic ovary syndrome (PCOS)
ea0003p210
Parathyroid polyhormone action on motility of pregnant mouse uterus in vitro: Role of nitric oxide
ea0003p211
Phenotype and insulin resistance (IR) in polycystic ovary syndrome (PCOS) among South Asians (SA) and Caucasians (C): Is there a difference?
ea0003p212
Detection of bio-inactive prolactin (macroprolactin) is analyser dependant
ea0003p213
Awareness of Libyan women of the menopause and their attitudes to hormone replacement therapy
ea0003p214
The mRNA expression and regulation of natural antimicrobials in human fetal membranes and placenta
ea0003p215
Activation of supraoptic nucleus (SON) oxytocin neurones during mouse parturition
ea0003p216
Residual ovarian function after cytotoxic chemotherapy and possible predictors of ovarian recovery
ea0003p217
A randomised controlled trial comparing the use of metformin and dianette in hirsutism associated with PCOS
ea0003p218
Testicular Leydig cell tumour presenting as primary infertility
ea0003p219
Phytoestrogens as inhibitors of aromatase and 17beta-hydroxysteroid dehydrogenase type 1 in luteinized human granulosa cells
ea0003p220
Oxygen tension regulates placental 11 beta-hydroxysteroid dehydrogenase type 2
ea0003p221
Androgen status and female sexual dysfunction in healthy pre-menopausal women
ea0003p222
A novel sensitive radioimmunoassay for the measurement of soluble Flt-1 (soluble vascular endothelial growth factor receptor-1)
ea0003p223
Improvement of hyperandrogenism and insulin resistance in females with severe obesity after weight loss through bariatric surgery
ea0003p224
Oral clatharate-DHEA as a potential form of androgen replacement in hypogonadal men. A phase 2, open label, placebo controlled, parallel group pharmacokinetic study
ea0003p225
Significant ethnic variation in circulating total bound and free testosterone
ea0003p226
Increased HOXA10 expression in late gestation: A novel target for hormonal regulation in placenta and decidua
ea0003p227
Efficacy of metformin for ovulation induction in polycystic ovary syndrome
ea0003p228
Expression of mRNA for IGF-1, IGF-2, type 1-IGF receptor, type 2-IGF receptor and insulin receptor in isolated, human preantral follicles
ea0003p229
FSH alters metabolism and increases chromosomal abnormalities in mouse cumulus-oocyte-complexes matured in vitro
ea0003p230
Engineering of single chain antibodies selected from a phage display library into human IgGs that recognise gonadotrophin surge-attenuating factor (GnSAF) bioactivity
ea0003p231
1,25-dihydroxyvitamin D3 receptors (VDR) are present on human granulosa cells and cells of the corpus luteum
ea0003p232
Semen profile, hormonal analysis and physiological activity of Pakistani men with varying degrees of sperm concentrations
ea0003p233
Effectiveness of antioxidant vitamin therapy in improving semen quality
ea0003p234
Regulation of expression and activity of lysyl oxidase in developing ovarian follicles
ea0003p235
Signalling
Do inhibitors of NAD(P)H oxidase improve endothelial function in rat and human arteries?
ea0003p236
Analysis of GR/NFkB interactions in living cells
ea0003p237
Interactions of vitamin D analogues with downstream effectors of insulin-like growth factor 1 (IGF-I) signalling
ea0003p238
Dexamethasone blocks mitochondrial targeting-induced apoptosis
ea0003p239
Expression and function of voltage-gated calcium channels in human pancreatic B-cells in health and disease
ea0003p240
Mutations in the growth hormone receptor (GHR) may differentially affect signalling and receptor trafficking
ea0003p241
Essential role of p38 mitogen-activated protein kinase in adipogenesis
ea0003p242
Steroids
Free cortisol index in suspected HPA axis pathology
ea0003p243
Expression and corticosteroid regulation of serum and glucocorticoid regulated kinase, and epithelial sodium channel subunits in human ocular ciliary epithelium
ea0003p244
Carbenoxolone, an inhibitor of 11 beta hydroxysteroid dehydrogenase type 1, reduces intraocular pressure in patients with ocular hypertension
ea0003p245
Comparison of the efficacy of long-term self-administration of subcutaneous human chorionic gonadotrophin with intramuscular exogenous testosterone (Sustanon) in male hypogonadism
ea0003p246
The prevalence and morbidity of long-term oral corticosteroid therapy
ea0003p247
The relationship between smoking, statin therapy and testosterone in men with coronary artery disease
ea0003p248
Androgens and diabetes mellitus in men with coronary artery disease
ea0003p249
Testosterone and pro-inflammatory cytokines in men with chronic heart failure
ea0003p250
Testosterone therapy improves depressive symptoms in men with chronic heart failure
ea0003p251
Testosterone increases interleukin 10, an anti-inflammatory cytokine, in whole blood from hypogonadal men
ea0003p252
Testosterone and skeletal muscle parameters in men with chronic heart failure
ea0003p253
Hypoglycaemia and Addison's disease - cause or association?
ea0003p254
Intermittent hyponatraemia due to isolated ACTH deficiency
ea0003p255
Expression of adipose 11 beta-hydroxysteroid dehydrogenase type 1 in human obesity
ea0003p256
Enhanced hepatic A-ring reduction of glucocorticoids in obesity: Regulation by glucocorticoids and insulin
ea0003p257
In vitro expression of catalytically active human aldosterone synthase
ea0003p258
Reduced glucocorticoid receptor expression in obese Zucker rats: Protection from the metabolic consequences of obesity?
ea0003p259
Assessment of mineralocorticoid status by urinary corticosteroid profiling using gas chromatography-mass spectrometry (GCMS)
ea0003p260
Angiotensin II and ACTH differentially regulate adrenal steroid production through key steroidogenic enzymes
ea0003p261
A role for nur-77 in the regulation of adrenal steroid production
ea0003p262
Growth hormone increases fat mass in patients with simple obesity
ea0003p263
Cortisone reductase (11 beta-hydroxysteroid dehydrogenase type 1) deficiency presenting with features of late onset congenital adrenal hyperplasia
ea0003p264
Phytoestrogen dietary supplementation does not alter serum IGF-1 levels in postmenopausal women
ea0003p265
Testosterone exhibits a calcium antagonistic action upon store operated calcium channels in cultured vascular smooth muscle cells
ea0003p266
Testosterone does not increase the production of cyclic AMP (cAMP) in cultured vascular smooth muscle cells
ea0003p267
Circulating steroid levels in the testicular feminised (Tfm) mouse
ea0003p268
Size at birth, gestational age and cortisol secretion in adult life: Do multiple mechanisms underlie fetal programming of the hypothalamic-pituitary-adrenal axis?
ea0003p269
Roles of K-Ras and Gadd153 in 17beta-oestradiol-induced apoptosis in colo205 cells
ea0003p270
Fetal and maternal regulation of aldosterone synthase and 11 beta hydroxylase
ea0003p271
Quantification of aldosterone synthase (CYP11B2 ) gene expression in the adrenal gland and central nervous system following dietary sodium manipulation
ea0003p272
Long-term overall success after transsphenoidal surgery for Cushing's disease: Time for a reappraisal of therapy?
ea0003p273
What value do cortisol measurements provide in monitoring metyrapone therapy?
ea0003p274
Thyroid
Atrial fibrillation predicts mortality in thyrotoxicosis
ea0003p275
Increased force/unit cross sectional area as well as increased bulk causes recovery in proximal strength in hyper/hypothyroidism
ea0003p276
Influence of pre-treatment factors on outcomes following the use of high fixed dose radioiodine treatment for hyperthyroidism
ea0003p277
The female preponderance to autoimmune thyroid disease is reduced in multiplex type 1 diabetes families
ea0003p278
Analysis of a clinical workstation thyrotoxicosis share-care scheme
ea0003p279
Thyrotoxic heart failure in a previously fit 40 year old woman
ea0003p280
Delayed resolution of endothelial dysfunction despite biochemical correction of thyrotoxicosis
ea0003p281
Thyroid function in paediatric patients with malignancy after radiotherapy in Isfahan, Iran
ea0003p282
Thyroid hormone (TH) regulation of iodothyronine deiodinase and thyroid hormone receptor (TR) expression in placental trophoblast cells
ea0003p283
Pituitary tumor transforming gene and basic fibroblast growth factor-2 - novel potential molecular indicators for thyroid cancer
ea0003p284
Outcome at two years of fixed dose radioiodine treatment for thyrotoxicosis
ea0003p285
Effect of blood exchange transfusion on neonatal thyroid function
ea0003p286
Provision of a new strength thyroxine tablet would facilitate tight control of TSH concentrations in primary hypothyroidism
ea0003p287
The follow-up status of patients 10 years after treatment with radioactive iodine(RI) for hyperthyroidism
ea0003p288
A cluster of cases of subacute thyroiditis in North East England
ea0003p289
Audit of the management of maternal hypothyroidism in pregnancy: Implications for service provision
ea0003p290
Lithium associated thyrotoxicosis
ea0003p291
Thyroid dysfunction in diabetes: Can we justify routine screening?
ea0003p292
Clinical assessment of two methods for measuring thyrotropin binding inhibiting immunoglobulin (TBII)
ea0003p293
Thyroid peroxidase antibodies are not a surrogate for thyroid stimulating antibodies in the investigation of the etiology of thyrotoxicosis
ea0003p294
Molecular characterisation of congenital hypothyroidism
ea0003p295
Pyrimidine and purine metabolism in human leukocytes in autoimmunological thyroid diseases - RNA expression of some enzymes
ea0003p296
Protein kinase C delta interacts with the sodium iodide symporter (NIS) to increase its activity in human thyrocytes
ea0003p297
Profile of the thyroid function in a population with type-2 diabetes mellitus
ea0003p298
Thyroid function in early pregnancy. A prospective study
ea0003p299
Determining the molecular causes of hyperthyroidism
ea0003p300
Telephone follow-up following radioiodine therapy for thyrotoxicosis improves outcome
ea0003p301
Environmental factors produce variation within a model of thyroid eye disease
ea0003p302
The use of lithium as an adjunct to radioiodine therapy for thyrotoxicosis
ea0003p303
Adenoviral expression of secreted Tie-2 reduces thyroid follicular cell growth and adhesion
ea0003p304
Primary hypothyroidism and unilateral thyroid eye disease: A case report
ea0003p305
Plasma total and free tissue factor pathway inhibitor, tissue plasminogen activator antigen, and plasminogen activator inhibitor antigen levels in various thyriod disorders
ea0003p306
High thyroglobulin autoantibodies in Sri Lankan tamil tea workers exhibit an epitope-recognition pattern distinct from healthy subjects and autoimmune thyroid disease (AITD) patients
ea0003p307
Thyroid disease in patients with genetic haemochromatosis - A prospective study
ea0003p308