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SFE2003
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194th Meeting of the Society for Endocrinology and Society for Endocrinology joint with Diabetes UK Endocrinology and Diabetes Day
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Summary
Abstracts
Contents
Plenary Lectures
Society for Endocrinology Asia and Oceanic Medal Lecture
New insights into growth hormone action
ea0006s1
Society for Endocrinology Asia and Oceanic Medal Lecture
ea0006s1biog
Society for Endocrinology European Medal Lecture
GHRELIN AND SYNTHETIC GHS
ea0006s2
Society for Endocrinology European Medal Lecture
ea0006s2biog
Society for Endocrinology Medal Lecture
Has the mechanism by which the endocrine placenta scavenges the mother whilst sparing the foetus been unmasked?
ea0006s3
Society for Endocrinology Medal Lecture
ea0006s3biog
Basic Science Review Session
(1)
Y Are Men The Weaker Sex?
ea0006s4
Symposia
Newer concepts of mineralocorticoid action
Extra-adrenal aldosterone synthesis and its role in non-classical target tissues
ea0006s5
GENETIC DISORDERS OF MINERALOCORTICOIDS
ea0006s6
DIAGNOSIS OF HYPOALDOSTERONISM
ea0006s7
Treating Primary Aldosteronism with New Aldosterone Receptor Antagonists
ea0006s8
Gaseous signalling
AN OVERVIEW OF GASEOUS SIGNALING BY NITRIC OXIDE
ea0006s9
HIF and cancer
ea0006s10
NO signalling and endogenous methylarginines
ea0006s11
THE HEME OXYGENASE-CARBON MONOXIDE PATHWAY IN THE CONTROL OF NEUROENDOCRINE FUNCTION
ea0006s12
Melanocortin receptors
Role of Brainstem Melanocortin System in CCK-mediated Satiety
ea0006s13
Brain melanocortin receptors - feeding and energy expenditure
ea0006s14
N-terminal POMC ligands and their receptors
ea0006s15
Melanocortin receptors in the anterior pituitary
ea0006s16
The endocrinologist and bone
OSTEOPOROSIS IN INFLAMMATORY BOWEL DISEASE
ea0006s19
11beta-hydroxysteroid dehydrogenase type 1: a prereceptor regulator of glucocorticoids in bone
ea0006s20
Parathyroid hormone in the treatment of osteoporosis: The Dawn of the anabolic era
ea0006s21
Statins and Bone
ea0006s22
Clinical Endocrine Debate
This house believes that the investigation of thyroid nodules should be simplified to a syringe and needle
The case for
ea0006s17
The case against
ea0006s18
Nurses Session
Steroid replacement
Steroid Replacement Therapy
ea0006s23
A Simplfied Protocol for Hydrocortisone Replacement Therapy in Patients with Adrenal Insufficiency
ea0006s24
AN AUDIT OF SELF-CARE OF PATIENTS ON HYDROCORTISONE REPLACEMENT THERAPY
ea0006s25
Steroid replacement therapy: the challenges of medication management in adrenal insufficiency, with reference to insights from patients' experiences
ea0006s26
Oral Communications
Young Endocrinologist Session
Bicuspid Aortic Valve is associated with increased arterial stiffness in adult women with Turner Syndrome
ea0006oc1
The nature of the quality of life (QOL) impairment in adult GHD survivors of cancer and their response to GH replacement therapy
ea0006oc2
Recurrent painful unilateral Gynaecomastia with relapsing Hyperthyroidism
ea0006oc3
Influence of Annexin 1 gene deletion on dopaminergic cell numbers in the mid-brain
ea0006oc4
Non-genomic Progesterone Receptors in Human Endometrium
ea0006oc5
Crosstalk between IGF signalling and cadherin-mediated cell adhesion promotes myogenic differentiation
ea0006oc6
Reproduction
IGF-I STIMULATES EARLY FOLLICULAR DEVELOPMENT IN CULTURED HUMAN OVARIAN TISSUE
ea0006oc7
Inverse relationship between aromatase and connective tissue growth factor (CTGF) during rat granulosa cell differentiation
ea0006oc8
Prokineticins (EG-VEGF and Bv8) and their receptors (PKR1 and PKR2) in the human endometrium
ea0006oc9
PROSTAGLANDIN EP2 RECEPTOR PROMOTES VEGF EXPRESSION VIA THE EGFR AND ERK1/2 SIGNALLING PATHWAYS
ea0006oc10
EFFECT OF DIETARY N-6 POLYUNSATURATED FATTY ACIDS (PUFAS) ON PROSTAGLANDINS (PG) PRODUCED BY MATERNAL INTERCOTYLEDONARY ENDOMETRIAL (IC) TISSUES IN LATE PREGNANT EWES
ea0006oc11
SERUM C-REACTIVE PROTEIN (CRP) IS RELATED TO AGE AND BODY MASS INDEX (BMI) IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME (PCOS) BUT NOT TO INSULIN SENSITIVITY
ea0006oc12
Resistance to insulin-dependent glucose metabolism in human granulosa-luteal cells from anovulatory women with polycystic ovaries
ea0006oc13
Expression and signaling characteristics of orexin receptors in the human male reproductive system
ea0006oc14
Growth and Development
Spontaneous differentiation of mouse embryonic stem cells into an islet phenotype
ea0006oc15
Overexpression of insulin-like growth factor binding protein-5 (Igfbp5) in mice results in compromised muscle development
ea0006oc16
BONE MORPHOGENETIC PROTEIN-2 - RECEPTOR EXPRESSION AND FUNCTION IN PITUITARY GONADOTROPHS
ea0006oc17
Testosterone 17beta-hydroxysteroid dehydrogenase (17beta-HSD) activities of mouse type I and VI 3beta-hydroxysteroid dehydrogenases
ea0006oc18
DIFFERENTIAL EFFECTS OF MATERNAL NUTRITION ON MOLECULAR INDICES OF FETAL ADIPOSE TISSUE DEVELOPMENT AND FUNCTION
ea0006oc19
THE EFFECT OF MATERNAL NUTRITION DURING THE FIRST OR SECOND HALF OF GESTATION ON GLUCOSE TOLERANCE OF THE SOW
ea0006oc20
CHRONIC UMBILICAL CORD COMPRESSION BLUNTS THE FETAL PLASMA ARGININE VASOPRESSIN (AVP) RESPONSE TO SUBSEQUENT ACUTE HYPOXAEMIA
ea0006oc21
REASSESSMENT OF GROWTH HORMONE STATUS IS REQUIRED AT FINAL HEIGHT IN CHILDREN TREATED WITH GROWTH HORMONE REPLACEMENT FOLLOWING RADIATION THERAPY
ea0006oc22
Neuroendocrinology
Receptor Shedding: A Novel Mechanism for the Disinhibition of CNS Neuronal Growth
ea0006oc23
PACAP STIMULATES PHOSPHORYLATION AND LIGAND-BINDING ACTIVITY OF STEROIDOGENIC FACTOR-1 (SF-1) IN alphaT3-1 GONADOTROPHS
ea0006oc24
Sexual dimorphism in anterior pituitary function in the annexin 1 knockout mouse
ea0006oc25
Suppression of the hypothalamo-pituitary adrenal axis by long-term intra-arcuate Cocaine- and Amphetamine-regulated transcript (CART) peptide
ea0006oc26
The MC3-R does not play a role in mediating the effects of gamma-MSH peptides on the adrenal
ea0006oc27
Safety And Efficacy Of Converting Patients With Acromegaly From Long-Acting Octreotide To Pegvisomant
ea0006oc28
EFFICACY AND SAFETY OF TITRATED-DOSES LANREOTIDE AUTOGEL IN PATIENTS WITH ACROMEGALY
ea0006oc29
Circulating Cocaine- and Amphetamine-regulated transcript (CART) peptide in subjects with abnormalities of the hypothalamo-pituitary axis
ea0006oc30
Poster Presentations
Clinical case reports
A young woman with allergic rhinitis and proximal myopathy
ea0006p1
A CASE OF HYPERTHYROIDISM PRESENTING AS HAEMATOLOGICAL MALIGNANCY
ea0006p2
PROFOUND HYPOTHYROIDISM IN A PATIENT WITH LACTOSE INTOLERANCE
ea0006p3
Acromegaly with Optic Atrophy in a case of Macroadenoma of pituitary with no pressure effect on Optic Chiasm
ea0006p4
An unusual case of phaeochromocytoma
ea0006p5
Gestational DI and oligohydramnios
ea0006p6
Tuberous Sclerosis and Cushing's syndrome: a rare association
ea0006p7
Tall or thin
ea0006p8
A RARE CAUSE OF HYPOGLYCAEMIA
ea0006p9
Transphenoidal basal encephalocoele presenting with panhypopituitarism
ea0006p10
NOW YOU SEE IT, NOW YOU DON'T: A VARIABLE PITUITARY MASS
ea0006p11
Uneventful pregnancy in a patient with pituitary apoplexy
ea0006p12
Surgical treatment for insulinoma and disappearance of type 2 diabetes mellitus
ea0006p13
Relapsing lymphocytic hypophysitis with progressive hypopituitarism and permanent neurological deficit
ea0006p14
A Case of ACTH Secreting Benign Mediastinal Carcinoid with Hypocalcaemia
ea0006p15
What is the Clinical Relevance of Macroprolactinaemia? A Clinical Case Report
ea0006p16
PERSISTENT VOMITING: AN UNCOMMON PRESENTING SYMPTOM OF THYROTOXICOSIS IN A WOMAN WITH TYPE 1 DIABETES MELLITUS
ea0006p55
RECOGNIZING PARATHYROID CARCINOMA
ea0006p56
Cytokines
EFFECT OF CATHEPSIN D AND PROSTATE SPECIFIC ANTIGEN ON LATENT TRANSFORMING GROWTH FACTOR-BETA IN BREAST CANCER CELL LINES
ea0006p17
EFFECT OF MATERNAL NUTRIENT RESTRICTION DURING LATE-GESTATION ON THE HEPATIC INSULIN-LIKE GROWTH FACTOR (IGF) SYSTEM IN NEONATAL SHEEP
ea0006p18
EFFECT OF CHRONIC PROLACTIN ADMINISTRATION ON THE SOMATOTROPHIC AXIS IN ONE-WEEK-OLD LAMBS
ea0006p19
INVESTIGATION OF GROWTH HORMONE SECRETION AND SENSITIVITY IN RHEUMATOID ARTHRITIS
ea0006p20
GH and nitric oxide production by pig pituitary cells in different culture conditions
ea0006p21
Pro-adrenomedullin N terminal 20 peptide (PAMP) causes proliferation of human endothelial and adrenocortical cells
ea0006p22
Diabetes, metabolism and cardiovascular
Relationship between insulin resistance and exercise test parameters in asymptomatic type II diabetics without any documented evidence of coronary artery disease
ea0006p23
Pancreatic islet protective effect of vanadium in streptozotocin-induced diabetic rats, histological, immunohistochemical and ultrastructural study
ea0006p24
Testosterone-Induced Vasodilatation Of Isolated Human Mesenteric Resistance Arteries Is Independent Of The Vascular Endothelium
ea0006p25
The relationship between serum levels of testosterone and inflammatory cytokines in men wih coronary artery disease
ea0006p26
HYPERTENSION AND PLASMA RENIN ACTIVITY IN WOMEN WITH TURNER SYNDROME
ea0006p27
DOES INSULIN FORMULATION MATTER IN ANTENATAL DIABETES CARE?
ea0006p28
THE EFECTS OF ACUTE HYPERINSULINEMIA AND INSULIN SENISTIVITY ON PLASMA HOMOCYSTEINE IN NON-OBESE WOMEN WITH POLYCYSTIC OVARY SYNDROME
ea0006p29
Endocrine tumours and neoplasia
Extracts from the Marine Sponges Anthosigmella varians (AV) and Spongia barbara (SB) Lower Cyclin B1 Levels, Cause a G2/M Cell Cycle Block and Trigger Apoptosis in SW-13 Human Adrenal Carcinoma Cultures
ea0006p30
CYCLOSPORIN A ENHANCES CERAMIDE SIGNALLING IN HUMAN BREAST CANCER CELLS IN RESPONSE TO N-(4-HYDROXYPHENYL) RETINAMIDE
ea0006p31
TITLE: Acquired prolactin deficiency (APD) reflects residual pituitary function after treatment for Cushing's disease
ea0006p32
PHAEOCHROMOCYTOMA AND MULTIFOCAL GASTROINTESTINAL STROMAL TUMOURS:CARNEY TRIAD VARIANT OR A NEW SYNDROME?
ea0006p33
AN AUDIT OF SESTAMIBI SCANNING IN THE INVESTIGATION OF PRIMARY HYPERPARATHYROIDISM
ea0006p34
THE SENSITIVITY OF (super)123I-MIBG IN THE DETECTION OF HISTOLOGICALLY CONFIRMED CATECHOLAMINE-PRODUCING TUMOURS
ea0006p35
Macroprolactinomas in men: long-term efficacy of bromocriptine treatment
ea0006p36
Normalisation of serum IGF-I by pegvisomant is not associated with a reduction in median nerve size in patients with active acromegaly
ea0006p37
Ghrelin and a Novel Ghrelin Isoform Have Potential Autocrine/Paracrine Roles in Hormone-Dependent Cancer
ea0006p38
Use of Continous glucose monitoring system in the medical management of insulinomas
ea0006p39
The effect of pegvisomant therapy on plasma levels of matrix metalloproteinases 2, 9 and vascular endothelial growth factor in patients with acromegaly
ea0006p40
Intraoperative parathyroid hormone (PTH) determinations
ea0006p41
SUBCLINICAL GROWTH HORMONE EXCESS, SIGNIFICANT OR IRRELEVANT?
ea0006p42
Growth and development
EFFECTS OF MATERNAL COLD EXPOSURE DURING LATE GESTATION ON GHRELIN mRNA ABUNDANCE IN THE OVINE LIVER
ea0006p43
CHRONIC UMBILICAL CORD COMPRESSION BLUNTS THE ARGININE VASOPRESSIN RESPONSE TO SUBSEQUENT ACUTE HYPOXAEMIA IN SHEEP DURING LATE GESTATION
ea0006p44
Effect of protein supplementation to the mother at specific stages of gestation on fetal adipose tissue
ea0006p45
The influence of birth weight on adipose tissue (AT) uncoupling protein 3 (UCP3) expression and thyroid regulation in neonatal pigs
ea0006p46
Lanreotide Autogel in acromegaly: a pharmacokinetic and pharmacodynamic analysis
ea0006p47
QLS-H, A MEASURE OF QUALITY OF LIFE IN ADULT UK GHD PATIENTS
ea0006p48
Neuroendocrinology and behaviour
QLS-H, A MEASURE OF QUALITY OF LIFE IN ADULT UK GHD PATIENTS
ea0006p49
The oxytocin response to increased plasma sodium following ovariectomy and oestrogen replacement
ea0006p50
Bone
sRANK-L AND OPG ARE INCREASED IN SOME OSTEOPOROTIC PATIENTS
ea0006p52
VITAMIN D INSUFFICIENCY AND PLASMA LEVELS OF sRANK-L and OPG IN OSTEOPOROTIC WOMEN
ea0006p53
sRANK-L AND OPG CORRELATE WITH BONE MINERAL DENSITY IN OSTEOPOROSIS
ea0006p54
Reproduction
Ovarian follicle culture: an old technique revisited
ea0006p57
Audit of the effects of Sibutramine and Metformin in the management of Polycystic Ovarian Syndrome - clinical experience from an endocrine clinic
ea0006p58
Vascular endothelial growth factor (VEGF), its receptors (KDR and Flt-1) and eNOS are up-regulated in the rat uterine cervix during pregnancy
ea0006p59
Aromatase is abundantly expressed in neonatal rat penis but down-regulated in adulthood
ea0006p60
Prostaglandin production and timing of parturition in sheep fed a diet high in n-6 polyunsaturated fatty acids
ea0006p61
Hyperemesis in pregnancy not the usual suspects
ea0006p62
THE INFLUENCE OF POLYCYSTIC OVARY SYNDROME ON OVARIAN GENE EXPRESSION
ea0006p63
Steroids
The short synacthen test and the overnight metyrapone test in the investigation of adrenal suppression in patients on prednisolone therapy
ea0006p64
Opposite effects of dexamethasone and oestardiol on annexin 1 expression
ea0006p65
Hydrocortisone Induced Inhibition of Nuclease Activities in Rat Liver Nuclei
ea0006p66
DESIGN OF OESTROGEN RESPONSIVE REPORTER CONSTRUCTS FOR USE IN CELL CULTURE: USE OF CMV PROMOTER
ea0006p67
Estradiol Action on Phospholipid Composition of Rat Liver Chromatin
ea0006p68
REDUCED EXPRESSION OF 11BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 2 IN KIDNEY BIOPSIES OF PATIENTS WITH RENAL FAILURE
ea0006p69
Effects of food deprivation on the expression and signalling of orexin and orexin receptors in the rat hypothalamus and adrenal gland
ea0006p70
OESTROGEN RECEPTOR ALPHA (ERalpha) BUT NOT OESTROGEN RECEPTOR BETA (ERbeta) EXPRESSION IS DOWNREGULATED BY DEXAMETHASONE IN HUMAN SCALP HAIR DERMAL PAPILLA CELLS
ea0006p71
Normal Synacthen Test response and Evolution of Schmidt's Syndrome in brittle Type 1 Diabetes
ea0006p72
Thyroid
An epidemiological clinical study on Ukrainian patients with severe postoperative hypoparathyroidism using a new questionnaire instrument
ea0006p51
Management of thyroid nodule Audit
ea0006p73
AN AUDIT OF THE MANAGEMENT OF DIFFERENTIATED THYROID CANCER IN A SPECIALIST CLINIC IN A LARGE DISTRICT HOSPITAL
ea0006p74
An Audit of Initial Management of Thyroid Nodules in secondary care
ea0006p75
Urticaria The Presenting Symptom Of Thyrotoxicosis
ea0006p76
Lectures
Hypertension and diabetes
Mechanism of hypertension-mediated end-organ damage in diabetes
ea0006ds1
Mechanisms contributing to hypertension in type 2 diabetes
ea0006ds2
Epidemiology of hypertension and diabetes
ea0006ds3
Symposium
Hypertension
Genetics: Polymorphisms linking hypertension and type 2 diabetes
ea0006ds4
Vascular cell dysfunction in hypertension and diabetes
ea0006ds5
Diabetes amp Hypertension: Causes, Investigations and Management
ea0006ds6
Expert Session
Diabetes
Hypoglycaemia
ea0006ds7
Diabetes and Pregnancy
ea0006ds8
Debate
Management of the hypertensive diabetic patient
Diabetic Hypertension: Best left to the Diabetologist
ea0006ds9
Diabetic Hypertension: Best Left to the Cardiologist
ea0006ds10
Poster Presentations (1)
Diabetes, metabolism and cardiovascular
Silent myocardial ischemia in patients with type II diabetes mellitus without the clinical manifestations of ischemic heart disease in Turkish population
ea0006dp1
Diurnal variation in insulin sensitivity
ea0006dp2
Pancreatic islet protective effect of vanadium in streptozotocin-induced diabetic rats, histological, immunohistochemical and ultrastructural study
ea0006dp3
AMBULATORY BLOOD GLUCOSE MEASUREMENT IN A NON-PATIENT GROUP OF WOMEN REPORTING SYMPTOMS OF REACTIVE HYPOGLYCAEMIA
ea0006dp4
AN AUDIT OF THE MANAGEMENT OF DIFFERENTIATED THYROID CANCER IN A SPECIALIST CLINIC IN A LARGE DISTRICT HOSPITAL
ea0006dp5
An unusual case of phaeochromocytoma
ea0006dp6
MODULATION OF NICOTINE MEDIATED RESPONSES IN HUMAN GINGIVAL FIBROBLASTS BY PLATELET DERIVED GROWTH FACTOR (PDGF) AND THE ALKALINE PHOSPHATASE INHIBITOR LEVAMISOLE
ea0006dp7
TRANSFORMING GROWTH FACTOR BETA (TGF) and INSULIN LIKE GROWTH FACTOR (IGF) MEDIATED RESPONSES, TO SERIAL CONCENTRATIONS OF NICOTINE, USING ANDROGEN BIOMARKERS IN HUMAN GINGIVAL FIBROBLASTS
ea0006dp8
Treatment of metabolic syndrome with topiramate. An open study
ea0006dp9
Confirmation of altered hypoglycaemia awareness by structured questionnaire and continuous ambulatory glucose profiles in those with Type 1 diabetes mellitus complicated by severe hypoglycaemia
ea0006dp10
A Prospective Audit of Triple Therapy in Type 2 Patients
ea0006dp11
NOW YOU SEE IT, NOW YOU DON'T: A VARIABLE PITUITARY MASS
ea0006dp12
ASYMPTOMATIC TYPE 1 DIABETES MELLITUS
ea0006dp13
Onset of insulin-resistant stage in a Type II diabetic rat model is associated with diminished levels of vascular endothelial growth factor (VEGF) and its receptors in the penis: implications in the pathogenesis of erectile dysfunction in diabetes
ea0006dp14
Estradiol Action on Phospholipid Composition of Rat Liver Chromatin
ea0006dp15
An Audit of Initial Management of Thyroid Nodules in secondary care
ea0006dp16
THE EFFECT OF MATERNAL NUTRITION DURING THE FIRST OR SECOND HALF OF GESTATION ON GLUCOSE TOLERANCE OF THE SOW
ea0006dp17
PHAEOCHROMOCYTOMA AND MULTIFOCAL GASTROINTESTINAL STROMAL TUMOURS:CARNEY TRIAD VARIANT OR A NEW SYNDROME?
ea0006dp18
Effect Of The Mode Of Conception On Incidences Of Apoptotic And Proliferative Cells In Full Term Human Placentas
ea0006dp19
PITUITARY METASTASIS FROM AN UNKNOWN PRIMARY
ea0006dp20
An Audit On Adherence To Renal Guidelines in Prevention and Early Management of Renal disease in Type 2 Diabetes
ea0006dp21
A Case of ACTH Secreting Benign Mediastinal Carcinoid with Hypocalcaemia
ea0006dp22
Use of Continous glucose monitoring system in the medical management of insulinomas
ea0006dp23
Evidence for a cholinergic defect in the brain of the obese-diabetic (ob/ob) mouse
ea0006dp24
Effect of beta-endorphin on glucose uptake and muscle fatigue in resting and contracting muscles of normal and obese-diabetic (ob/ob) mice
ea0006dp25
SERUM C-REACTIVE PROTEIN (CRP) IS RELATED TO AGE AND BODY MASS INDEX (BMI) IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME (PCOS) BUT NOT TO INSULIN SENSITIVITY
ea0006dp26
DOES INSULIN FORMULATION MATTER IN ANTENATAL DIABETES CARE?
ea0006dp27
Prevalence and Management of Cardiovascular disease in a Diabetic-Renal cohort
ea0006dp28
Spontaneous differentiation of mouse embryonic stem cells into an islet phenotype
ea0006dp29
What is the Clinical Relevance of Macroprolactinaemia? A Clinical Case Report
ea0006dp30
Bicuspid Aortic Valve is associated with increased arterial stiffness in adult women with Turner Syndrome
ea0006dp31
Normal Synacthen Test response and Evolution of Schmidt's Syndrome in brittle Type 1 Diabetes
ea0006dp32
QLS-H, A MEASURE OF QUALITY OF LIFE IN ADULT UK GHD PATIENTS
ea0006dp33