Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2009) 19 P120

SFEBES2009 Poster Presentations Diabetes, Metabolism and Cardiovascular (49 abstracts)

Insulin resistance before and after parathyroidectomy in primary hyperparathyroidism

O Ajala , S Thondam & A Khaleeli


North Cheshire Hospitals NHS Trust, Warrington, UK.


Introduction: Primary hyperparathyroidism is associated with insulin resistance and reduced pancreatic beta cell function. Approximately 40% of patients with primary hyperparathyroidism have impaired glucose tolerance. This observational study sought to show improvement in insulin resistance after parathyroidectomy in patients with primary hyperparathyroidism.

Methods: Insulin resistance and pancreatic beta-cell function was calculated before and 12 weeks after parathyroidectomy in 16 patients. Insulin resistance was calculated using the homeostatic model assessment.


Results: Post parathyroidectomy, there was a reduction in Insulin resistance in 12 (75%) patients and increased beta cell function in 7 (44%) patients.

Conclusion: Our data shows a reduction in insulin resistance in a significant proportion of our study group.

/images/missingimage.jpg

Article tools

My recent searches

No recent searches.