ea0035p345 | Diabetes (epidemiology, pathophysiology) | ECE2014
, Yang Miao
, Wu Yu-wen
, Sun Su-xin
, Sun Jia-zhong
Objective: To investigate the effects of C1q/TNF related protein 3 CTRP3 on the insulin sensitivity of adipocyte and its possible mechanisms.Methods: The insulin resistance model of 3T3-L1 adipocyte was induced by palmic acid (PA) cultivation. Such adipocytes were treated with different concentration of recombinant CTRP3 (0,10,50,250,1250 ng/ml) for 12 h, and for different time (2, 6, 12, 24 h) at the concentration of 250 ng/ml. The glucose consumption w...