Searchable abstracts of presentations at key conferences in endocrinology
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17th European Congress of Endocrinology

Guided Posters

Reproduction: Female and other

ea0037gp.07.01 | Reproduction: Female and other | ECE2015

Preconceptional TSH and miscarriage in infertile women submitted to IVF

Vannucchi Guia , Covelli Danila , Renzini Mario , Brigante Claudio , Coticchio Giovanni , Canto Maria Beatrice Dal , Fadini Rubens , Dazzi Davide , Negro Roberto , Fugazzola Laura

It is known that high levels of TSH are associated with higher miscarriage risk, though the precise TSH cut-offs are debated. Aim of the present study was to evaluate if pre-conceptional TSH levels associate with increased risk of early miscarriage in a large series of infertile women submitted to IVF and to determine the threshold of TSH associated with the highest prevalence of pregnancy loss. We retrospectively studied 1484 infertile women (mean±age 36.7±4.1 years...

ea0037gp.07.02 | Reproduction: Female and other | ECE2015

Kisspeptin increased during reproductive ageing and is regulated by sympathetic nerve system

Fernandois Daniela , Marquez Ruth , Lara Hernan , Paredes Alfonso

Kisspeptin is found in the ovary of different species including human and rat. We have recently described, through in vitro studies, that kisspeptin is under the control of sympathetic innervation of the ovary. Considering that ovarian activity of sympathetic nerves increases with ageing, it is possible that the ovarian kisspeptin also increases during this period. As a role of kisspeptin in folliculogenesis has been postulated, this increase in kisspeptin could parti...

ea0037gp.07.03 | Reproduction: Female and other | ECE2015

The role of transvaginal ultrasonography in the evaluation of endometrial hyperplasia or cancer in pre- and perimenopausal women

Kim Sunmie , Hwang Kyu Ri , Kim Jin Ju , Kim Min-Jeong , Kim Seok Hyun

Objective: The aim of our study is to determine clinical factors and sonographic findings associated with endometrial hyperplasia or cancer (EH+) in pre- and perimenopausal women.Study design: A total of 14 340 transvaginal ultrasonography examinations of 9 888 healthy pre- and perimenopausal women were included in this retrospective study. One hundred sixty-two subjects underwent endometrial biopsy based on abnormal uterine bleeding (AUB), sonographic e...

ea0037gp.07.04 | Reproduction: Female and other | ECE2015

Expression of melanocortin receptors in human endometrium

Lantang Anastasia , Gan Earn , Innes Barbara , Pearce Simon , Lash Gendie

Background: The melanocortin system is known to be involved in hypothalamic regulation of energy balance, which is implicated in reproductive success. However, the peripheral role for melanocortin receptor (MCR) signalling in the reproductive system has not been described. During a clinical trial of repeated high dose tetracosactide (ACTH1–24) injection, four of nine premenopausal women with Addison’s disease developed menstrual disturbances. We wondered i...

ea0037gp.07.05 | Reproduction: Female and other | ECE2015

mRNA expressions of skin steroidogenic enzymes in women with idiopathic hirsutism

Taheri Serpil , Unluhizarci Kursad , Zararsiz Gokmen , Karaburgu Sulbiye , Borlu Murat , Ozgun Tuncay , Karaca Zuleyha , Tanriverdi Fatih , Dundar Munis , Kelestimur Fahrettin

Introduction: The pathogenesis of idiopathic hirsutism (IH) is not clear. On the other hand, human skin possesses all the enzymes necessary for androgen synthesis and catabolism indicating that it is an independent peripheral endocrine organ. Thus, in the present study we aimed to investigate the mRNA expression of aromatase enzyme and the other enzymes having functional roles in the steroidogenic pathway, in freshly obtained skin tissue from subumblical skin and the arm of wo...

ea0037gp.07.06 | Reproduction: Female and other | ECE2015

Difficulties in the evaluation of hirsutism using the modified Ferriman-Gallwey scale

Ciaplinskiene Lina , Kozloviene Dalia , Knispelis Robertas , Kriksciuniene Ruta , Zalinkevicius Rimas , Zilaitiene Birute

Inconsistences in hirsutism evaluation using The Modified Ferriman-Gallwey scale (mFG) between different evaluators and need for hirsutism diagnostics standardization has been reported in numerous publications.The aim of the study was to determine the differences in the evaluation of female hirsutism between researchers.Results: The study included healthy 20–34 year old (mean age 25.2 years, 95% CI 23.8–26.5) women with r...

ea0037gp.07.07 | Reproduction: Female and other | ECE2015

Incretin release in a different state of testosterone level among lean PCOS women – case control study

Mrozinska Sandra , Milewicz Tomasz , Rogatko Iwona , Kialka Marta , Spalkowska Magdalena , Migacz Kamila , Kowalczuk Aleksandra , Kawula Agnieszka , Galuszka-Bednarczyk Anna

Introduction: Incretins are peptide hormones, responsible for 70% of the insulin release after oral glucose intake. An impaired incretins secretion was noted in several conditions involving insulin resistance, including polycystic ovary syndrome (PCOS), known as the state with increased testosterone level. This paper considers a possible relationship between the level of free androgen index (FAI) and glucose-dependent insulinotropic peptide (GIP) among lean women affected by P...