Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2015) 37 EP405 | DOI: 10.1530/endoabs.37.EP405

ECE2015 Eposter Presentations Diabetes (complications & therapy) (143 abstracts)

Correlation of left ventricular hypertrophy and left ventricular diastolic dysfunction with HbA1c in newly diagnosed type 2 diabetics

Manish Gutch 1 , Syed Mohd Razi 1 , Abhinav Gupta 1 , Sukriti Kumar 2 & Keshav Gupta 1


1LLRM Medical College, Meerut, India; 2SGPGI, Lucknow, Uttar Pradesh, India.


Introduction: Diabetes is associated with dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Diabetic macrovascular complications are the leading cause of deaths in diabetics. The correlation between LVH and LVDD with HbA1c is not clear in newly diagnosed T2DM Indian diabetics.

Aims and objective: To study the frequency of left ventricular hypertrophy (LVH) and left ventricular diastolic dysfunction (LVDD) in normotensive newly diagnosed type 2 diabetic patients by using 2D echocardiography and correlation with HbA1c.

Materials and methods: The present study is an observational cross sectional study in which 100 newly diagnosed normotensive type 2 diabetes mellitus patients between 30 and 60 year of age were enrolled from endocrine OPD of a tertiary care centre during a period of 1 year. All cases were subjected to thorough clinical history, examination and 2D echocardiography along with HbA1c.

Observations and results: Out of 100 patients of newly diagnosed normotensive type 2 DM; 41% patients had LVDD and 37% patients had LVH. The mean HbA1c of population with LVDD was 7.67±0.90% and that with LVH was 7.74±0.91%. The LVDD and LVH were positively correlated with HbA1c (P value=0.0057 and 0.0011) respectively.

Conclusion: LVDD and LVH were positively correlated with HbA1c in newly diagnosed T2DM population.

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