Endocrine Abstracts

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The gastrointestinal tract is anatomically positioned to play a crucial role in the regulation of metabolic homeostasis, providing critical postingestive negative feedback to regulate both exogenous energy intake, as well as endogenous glucose production. This talk will highlight the ability of small intestinal lipid sensing to lower glucose production via a gut–brain–liver axis that is dependent on local gut peptide signaling. Furthermore, recent evidence indicates ...

In recent years, there has been a renewed interest in the role of dietary fibre in obesity management. Much of this interest stems from animal and human studies that suggest increased intake of fermentable fibre can improve body composition.A growing number of reports have demonstrated that the principal products of colonic fermentation of dietary fibre, short chain fatty acids (SCFAs), contribute to energy homeostasis via effects on cellular metabolic p...