Searchable abstracts of presentations at key conferences in endocrinology
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21st European Congress of Endocrinology

Lyon, France
18 May 2019 - 21 May 2019

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18-21 May 2019, Lyon, France

Guided Posters

Diabetes and Cardiovascular Disease

ea0063gp26 | Diabetes and Cardiovascular Disease | ECE2019

Association of MR-proANP with cardiovascular risk factors in middle aged patients with diabetes mellitus type 2 and non-diabetic controls

Chisaliita Simona , Wijkman Magnus , Nystrom Fredrik , Ostgren Carl Johan

Aim: To explore if MR-proANP is associated with cardio-metabolic risk factors in patients with med type 2 diabetes mellitus (T2D) and non-diabetic controls.Methods: MR-proANP was analyzed in 761 middle-aged (54–66years) patients with type 2 diabetes and 184 non-diabetic controls and related cardio-metabolic conventional risk factors as age, sex, previous cardiovascular diseases (atrial fibrillation, myocardial infraction), glucose, LDL cholesterol, ...

ea0063gp27 | Diabetes and Cardiovascular Disease | ECE2019

Serum insulin levels are associated with vulnerable plaque components in the carotid artery

Mujaj Blerim , Bos Daniel , Kavousi Maryam , Staessen Jan A , Franco Oscar H , Vernooij Meike

Background: Impaired insulin and glucose levels are implicated in the etiology of cardiovascular disease, however, their influence on the formation and composition of atherosclerotic plaque remains unclear.Purpose: To investigate the association between fasting serum insulin and glucose levels with atherosclerotic plaque composition in the carotid artery.Methods: In 1740 participants (mean age 72.9 years, 46% women, 14.4% diabetes ...

ea0063gp28 | Diabetes and Cardiovascular Disease | ECE2019

The synergistic impact of apolipoprotein B/ A-1 and lipoprotein (a) on coronary artery calcification

Ahn Chul Woo , Choi Arim , Kim Jung Hye , Park Kahui , Lee Sang Bae , Kim Yusik , Nam Ji Sun , Kang Shinae , Park Jong Suk

Objective: Apolipoprotein B/Apolipoprotein A-1 ratio (Apo B/Apo A-1) and lipoprotein (a) (Lp(a)) are known to be associated with atherosclerotic vascular disease. We investigated the influence of Apo B/Apo A-1 and Lp(a) on coronary artery calcification (CAC) among healthy Korean adults.Methods: A total of 1081 participants underwent cardiac computed tomography in health promotion center were enrolled. Anthropometric profiles and multiple cardiovascular r...

ea0063gp29 | Diabetes and Cardiovascular Disease | ECE2019

Systematic screening of masked hypertension in normotensive type 2 diabetic patients

Ghorbel Dorra , Hadjkacem Faten , Triki Faten , Mnif Mouna , Charfi Nadia , Rekik Nabila , Kammoun Samir , Abid Mohamed

Introduction: Masked hypertension (MH) is a relatively recent description leading to a similar cardiovascular risk as permanent hypertension. Masked hypertension is more common among diabetic patients.Methods: This was a case-control study. We performed 24-hour ambulatory BP in 53 type 2 diabetic patients normotensive in clinical measurement. We compared both Masked Hypertension and Normotensive groups according to clinical/laboratory parameters and targ...

ea0063gp30 | Diabetes and Cardiovascular Disease | ECE2019

Cardiovascular risk factors in patients with type 2 diabetes and non-alcoholic fat liver disease

Svetlana Rodionova , Elena Birukova , Larisa Zvenigorodskaya

Background and aims: To investigate the level of lipoprotein associated phospholipase A2 (LpPLA2), nitrogen oxide (NO) in patients with type 2 diabetes (DM2) and nonalcoholic fatty liver disease (NAFLD) against a variety of hypoglycemic therapies (HT).Materials and methods: A one-stage examination of 90 patients with DM 2 and NAFLD was carried out. Men ratio 37.8%, women ratio 62.2%, mean age 57.3±11.6 years. Mean HbAlc 7.4±1.82%. According to ...

ea0063gp32 | Diabetes and Cardiovascular Disease | ECE2019

Breastfeeding is inversely associated with subclinical atherosclerosis in postmenopausal women

Kaparos George , Apostolakis Michael , Armeni Eleni , Augoulea Areti , Paschou Stavroula A , Panoulis Konstantinos , Bakas Panagiotis , Georgiopoulos Georgios , Delialis Dimitrios , Deligeoroglou Efthymios , Stamatelopoulos Kimon , Lambrinoudaki Irene

Introduction: The aim of this study was to evaluate the association between a personal history of lactation and indices of subclinical atherosclerosis and arterial stiffness in postmenopausal women.Patients and methods: This cross-sectional study included 283 postmenopausal women. Sonographically assessed indices of vascular function [pulse wave velocity (PWV)] and vascular structure [intima-media thickness (IMT), atherosclerotic plaque presence] were te...

ea0063gp33 | Diabetes and Cardiovascular Disease | ECE2019

Application of 3D skin culture model as a tool to study the role of immune mechanisms in chronic diabetic foot ulcers pathogenesis

Mashkova Maryia , Goranov Vitaly , Mokhort Tatiana , Shyshko Alena , Mantachik Marina

The aim: To test cytotoxic effects of immune factors of patients with chronic diabetic foot ulcers on keratinocytes and fibroblasts in a 3D skin culture system.Materials and methods: In this study a multilayer 3D human skin model comprising of keratinocytes, fibroblasts and dendritic cells in an agarose-fibronectin gel was used. 20% serum of 13 patients with chronic noninfected diabetic foot ulcers, 13 diabetic type 2 patients and 13 healthy people and l...

ea0063gp34 | Diabetes and Cardiovascular Disease | ECE2019

Stroke in diabetic patients and cardiovascular risk factors control

Idougourram Soraya Leon , Martin Ana Barrera , Roman Angel Rebollo , Moreno Paloma Moreno , Laguna Maria Alcantara , Ortega Rafael Palomares , Moreno Maria Angeles Galvez

Introduction: Strokes are common diabetes macrovascular complications. A good control of cardiovascular risk factors such as glycemic control has been proven to reduce the risk of its appearance. Aim: Describe diabetes prevalence in patients admitted to hospital because of a stroke, as well as their treatment and metabolic control.Patients and methods: Observational retrospective study of patients admitted to the Neurology section because of a s...

ea0063gp35 | Diabetes and Cardiovascular Disease | ECE2019

Cardiovascular biomarkers and calculated risks - an association study

Markova Alexandra , Boyanov Mihail , Bakalov Deniz , Tsakova Adelina

The identification of type 2 diabetes patients at particularly high risk for cardiovascular events might be facilitated by the use of specific risk calculators or by measurements of serum biomarkers.Objectives: To correlate the levels of cardiovascular biomarkers – assymetric dymethylarginine (ADMA), endothelin 1 (ET-1), N-terminal brain natriuretic pro-peptide (NT-proBNP) and placental growth factor (PIGF-1), with calculated cardiovascular risks us...

ea0063gp36 | Diabetes and Cardiovascular Disease | ECE2019

Family education, quality of life and glycosylated haemoglobin control among Nigerian diabetics: a quasi-experimental study

Ojewale Lucia Y , Oluwatosin Abimbola

Glycaemic control remains poor among individuals with diabetes mellitus (DM) in Nigeria and is linked to a non-supportive family environment. Family-Integrated Diabetes Education (FIDE) has been shown to improve glycaemic control in studies among Hispanics and Caucasians. However, there is dearth of literature on its effectiveness among Africans; despite the close-knit nature of many African families. The study aimed at determining the effects of FIDE on glycosylated haemoglob...