Searchable abstracts of presentations at key conferences in endocrinology
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22nd European Congress of Endocrinology

05 Sep 2020 - 09 Sep 2020

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Europe's leading endocrinology congress showcasing the very best in the study and treatment of endocrine disorders.

Oral Communications

Environmental Endocrinology

ea0070oc8.1 | Environmental Endocrinology | ECE2020

The mosaic effects of endocrine disrupting chemicals mixtures on thyroid hormone levels: experimental study

Buha Aleksandra , Milovanovic Vesna , Bulat Zorica , Antonijevic Biljana

The lifelong exposure to mixtures of endocrine disrupting chemicals raises serious concerns about their deleterious effects on human health. Polychlorinated biphenyls (PCBs) had widespread use in numerous industrial applications, and were massively produced for several decades. After the discovery of the adverse effects of PCBs in the 1970s, brominated flame retardants (BFRs) were established as the major chemical flame retardant. Both chemicals persist in the environment and ...

ea0070oc8.2 | Environmental Endocrinology | ECE2020

Air pollution and incidence of hypertension in spanish adults [email protected] study

Valdes Sergio , Doulatram-Gamgaram Viyey , Maldonado-Araque Cristina , Lago-Sampedro Ana , Martín-Llorente Fernando , García-Vivanco Marta , Calle-Pascual Alfonso , Castaño Luis , Delgado Elias , Franch-Nadal Josep , Montanya Eduard , Rojo-Martinez Gemma

Introduction: The metabolic risk associated with air pollution could vary according to the specific pollution levels of each area, as well as factors related to lifestyle (diet, activity physical, socioeconomic status, tobacco), other exposures, comorbidities etc.. and has been insufficiently evaluated in our country.Objective: To study the association between long term exposure to air pollution (measured as PM concentrations) and the incidence of hypert...

ea0070oc8.3 | Environmental Endocrinology | ECE2020

Comparative histopathology of endocrine glands in phthalate exposed male Wistar rats unveil the vulnerability of adrenal gland and augmented by molecular docking

Ahmad Shahzad , Raisuddin Sheikh

Limited research has been conducted on adrenal gland as target of endocrine disrupting chemicals (EDCs). Moreover, studies on steroidogenesis as the target of EDCs has also attracted lesser attention compared to other metabolic pathways. We studied the effects of two extensively used phthalate esters viz., di-ethyl hexyl phthalate (DEHP) and di-butyl phthalate (DBP) on the adrenal gland in Wistar rats and checked its susceptibility against the exposure of these extensively use...

ea0070oc8.4 | Environmental Endocrinology | ECE2020

Cigarette smoking and the risk to develop symptoms of Hashimoto’s thyroiditis

Jabrocka-Hybel Agata , Skalniak Anna , Hubalewska-Dydejczyk Alicja

Introduction: Hashimoto’s thyroiditis (HT) is a complex disease which is caused by genetic as well as environmental factors. While the genetic predisposition to HT has been extensively investigated, the influence of most environmental factors still needs to be evaluated. Based on our previous study, we did not find any correlation between HT and the fact of cigarette smoking or the number of pack-years. We did, however, find a significant correlation between the age of s...

ea0070oc8.5 | Environmental Endocrinology | ECE2020

Effects of perinatal exposure to triclosan on neuronal development and behavior of mice

Jeong Sunhwa , Nam Tran Dinh , Myeong Go Seon , Bich Thuy Vo Thi , Jung Eui-Man , Jeung Eui-Bae

There have been raising concerns in the effects of endocrine disrupting chemicals like triclosan (TCS) on the embryo development. Triclosan (TCS) is commonly present in household and personal wash products We hypothesize that exposure to TCS during early stage of development could alter brain development affecting behavior. To test this hypothesis, primary cortical neurons were exposure to TCS with/without estrogen antiestrogen ICI 182780 from day in vitro 1 to 4. We also addr...

ea0070oc8.6 | Environmental Endocrinology | ECE2020

Temporal and spatial trends of operated cryptorchidism in France and environmental hypotheses: a nationwide study from 2002 to 2014

Le Moal Joëlle , Goria Sarah , Guillet Agnès , Rigou Annabel , Chesneau Julie

Introduction: Santé publique France develops a national epidemiological monitoring program to study health indicators related to endocrine disruptor exposure. Based on the weight of evidence, cryptorchidism was selected for this purpose. In this study, we aimed to analyze temporal, spatial and spatio-temporal trends of cryptorchidism during the period 2002–2014 in France, and explore and/or generate environmental hypotheses.Methods: We built a...