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Endocrine Abstracts (2022) 81 EP248 | DOI: 10.1530/endoabs.81.EP248

1Hospital Charles Nicolle, Endocrinology, Tunis, Tunisia; 2Hospital Charles Nicolle, Cardiology, Tunis, Tunisia


Introduction: Diabetes increases the risk of high blood pressure, atherosclerosis, coronary heart disease and stroke. Therefore, People with diabetes have an increased cardiovascular risk. Arterial stiffness is a marker of cardiovascular risk and has been shown to have an independent prognostic effect on cardiovascular disease. The aim of this study was to examine the relationship between cardiovascular risk and arterial stiffness in type 2 diabetes.

Methods: We conducted a prospective study including 249 diabetic patients without macroangipathic complications, between July 2020 and May 2021. Using a SphygmoCor®XCEL device, we measured arterial stiffness directly by the carotid to femoral pulse wave velocity (cfPWV).

Results: The mean age of the study population was 57.53±9.34 years (139 women and 110 men). The mean duration of the disease was 10.2 years.Our population were divided into two groups; high cardi-vascular risk 27.3% and very high cardio-vascular risk 72.7%.CfPWV > 10 m/s was found in 77.9% of the patients with high cardio-vascular risk and in 95% of the patients with a very high cardio-vascular risk.In the first group, cfPWV was at 11.92±2.08 m/s VS 14.29±2.79 m/s in the second group (P<0.001).

Conclusion: Arterial stiffness is often increased in type 2 diabetics. Moreover, it has been shown that it may predict cardiovascular events in asymptomatic individuals. Therefore, its evaluation in a high-risk population such as the diabetics, must be a routine in our daily practice.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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