ECE2022 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (318 abstracts)
Evaluation of pulse wave velocity in type 2 diabetes
Chayma Besrour 1 , Rojbi Imen 1 , Ben Ahmed Habib 2 , Mekni Sabrine 1 , Mchirgui Nadia 1 , Ben Nacef Ibtissem 1 & Khiari Karima 1
1Hospital Charles Nicolle, Endocrinology, Tunis, Tunisia; 2Hospital Charles Nicolle, Cardiology, Tunis, Tunisia
Introduction: Type 2 diabetes is an insidious and progressive disease; accounting for about 90% of all diabetes cases worldwide. Atherosclerosis is a common pathology in diabetes that involves a combination of fatty degeneration (atherosis) and stiffening of the arterial vessels (sclerosis), and the best tool to evaluate the arterial stiffness is the pulse wave velocity. The aim of this study is to evaluate the arterial stiffness in type 2 diabetic patients.
Methods: We conducted a prospective study including 249 diabetic patients without macroangipathic complications, between July 2020 and May 2021. Using a SphygmoCor®XCEL device, we measured arterial stiffness directly by the carotid to femoral pulse wave velocity (cfPWV).
Results: The mean age of the study population was 57.53±9.34 years (139 women and 110 men). The mean duration of the disease was 10.2 years. The mean body mass index was at 29.31±4.98 kg/m2 and the prevalence of obesity was at 41%.High blood pressure and dyslipidemia were present in 54.2% and 98.4% of patients. Microangiopathic complications were found in 58.2% of the patients. Only 24.5% of the patients had a controlled diabetes. Arterial stiffness defined as cfPWV > 10 m/s was present in 91.2% of the patients. And the mean cfPWV was at 13.64±2.82 m/s.
Conclusion: Arterial stiffness is often increased in type 2 diabetes. It is currently considered an essential link in the development of atherosclerosis and represents a new marker of cardiovascular risk. Carotid-femoral pulse wave velocity is the “gold-standard” method for assessing arterial stiffness in both populations; diabetics and the general population.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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