Endocrine Abstracts

Pregnancies in women with acromegaly are rare. Data from the literature report the absence of fetal malformation, a rarely symptomatic increase in adenomatous volume, a possible risk of gestational diabetes and gravidic hypertension in women not controlled before pregnancy. We report the case of a 32-year-old woman, nulliparous, who consults for spaniomenorrhea associated with chronic headaches, in whom the diagnosis of acromegaly was suspected in the face of a very discreet a...

Introduction: Prolactin-secreting tumors or prolactinomas comprise the most common pituitary tumor type, acconting of 47-66% of all pituitary tumors. These tumors can be treated with dopaminergic drugs (DA) however 10-15% of prolactinomas are DA resistant.Case 1: A 39 years old man followed for a geant agressif prolactinoma discovered following a progressive decline in visual acuity and associated with visual impairment (diplopia), the MRI of the sellar ...

Introduction: Pituitary adenomas, more recently referred to as pituitary neuroendocrine tumors (PitNets) from other organs, are common neoplasms comprising 10 to 20% on intracranial tumors. Null cell adenoma is a diagnosis of exclusion that requires immunonegativity for all adenohypophyseal hormones and a lack of cell type-specific transcription factors. It represents 0,6% of all pituitary tumors. Case: A 55 years old women with a history of treated thyr...

Introduction: Pituitary abscess (PA) is a rare accounting for 0,2-1% of all sellar lesions, it is generally classified as primary or secondary according to their etiopathogenesis. Case: A 20-year-old female with a history of vulvitis a year ago, dental abscesses on multiple dental caries who presented 05 months ago with intracranial hypertension syndrome in a febrile context. One-month later amenorrhea sets in as well as polyuropolydeptic syndrome, hormo...

Introduction: High-grade astrocytoma with piloid features (HGAP) is arecently described brain tumor entity defined by a specific DNA methylation profile. HGAP has been integrated in the World Health Organization classification of central nervous system tumors 2021.Clinical presentationA 53-year -old woman was admitted to our department with chief complaints of headache with rapid deterioration in visual acuity over a period of 6 months. During the course of the disease, the pa...

Background: Hypophysitis is a rare pathology its symptoms and radiological signs are non-specificy making its diagnosis difficultCase Description: A 62-year-old Women, mother of 5 children, with a History of type 2 diabetes mellitus, hypothyroidism. During a period of fasting, the patient presented with profound asthenia, a tendency to hypotension. A severe hyponatremia at 119 mmol/l was diagnosed. The patient received urgent treatment. The hormonal biol...

Background: Pituitary apoplexy (PA) is a rare neuroendocrine emergency due to acute ischemic infarction or hemorrhage of the pituitary gland. We report a case of apoplexy manifesting with isolated ophtalmoplégia.Case description: We report the case of a 48-year-old man with a history of hypertension, type 2 diabetes mellitus, and dyslipidemia. Consult a private ophthalmologist following the sudden appearance of double vision and sagging of the right...

Introduction: In 2020, Thyroid cancer was responsible for 586,000 cases worldwide, ranking in 9th place in terms of incidence. It is also the most common type of cancer of the endocrine system in 2020. According to the literature, thyroid cancer have reported an increase in the incidence worldwide. However, it varies greatly from country to country. The aim of this work was to evaluate the incidence of thyroid cancer and its trend in northern Tunisia between 1990 and 2019....

Introduction: One of the most common chronic diseases in adolescents is type 1 diabetes (T1D).This period of growth is characterized by hormonal fluctuations and psychological changes which are risk factors for diabetes imbalance.Aims: Describe the clinical, paraclinical and therapeutic profile in adolescents with type 1 diabetes in TunisiaMethods: Cross-sectional study conducted atthe Institute of Nutrition ...

Background: Type 1 diabetes mellitus is the most common chronic illness in childhood. His treatment involves a multifaceted regimen that includes daily blood glucose monitoring, insulin injections, a dietary plan, and regular exercise. Patients, especially during adolescence, do not fully adhere to the diabetes treatment and, as a result, they appear to be at risk for serious medical complications, including hyperglycemic episodes, Ketoacidosis and microvascular complications ...