Endocrine Abstracts

A 28-year-old female presented to ED with one week history of flu-like symptoms, palpitations, increasing breathlessness, and productive cough with copious sputum, of two days duration. There was h/o some weight loss over the last year, with episodic palpitations over the last 8-10 years that increased in frequency over the last one year. She had a family history of hyperthyroidism paternally and maternally. On examination, there was mild lid-lag and proptosis. She was tachypn...

Thyrotoxicosis causing hypokalaemic paralysis is a known complication among Asians, Myopathy as a result of thyrotoxicosis or caused by antithyroid drugs (ATD) is rare. Myositis, resulting in a rise in creatinine kinase levels (CK) is commonly seen in overt hypothyroidism, however, rapid lowering in circulating thyroid hormone levels during the treatment of Graves’ disease could result in myalgia and elevated CK levels. This complication needs to be actively diagnosed whe...

Introduction: Musculoskeletal disease is one of the common symptoms observed in people with diabetes. Shoulder pain is found to be the most common symptom and can lead to hindrance in daily activities that can directly or indirectly influence the metabolic processes of our body affecting the quality of life. Hence, we studied the prevalence of shoulder pain and its functional limitations among patients with uncontrolled diabetes mellitus (DM).Materials: ...

A 49-year old woman presented with four months history of drowsiness and weakness. She had twelve years history of intermittent menorrhagia, and was treated with iron and folic acid tablets, with partial relief. Clinically she was dehydrated, drowsy, pale and had pedal edema. Pelvic examination revealed a uterine mass 16 centimeter in diameter. Investigations- hemoglobin 9.0 gm/dl, peripheral smear microcytic, hypochromic anemia,serum albumin- 2.8 g/dl (3.6–4.7 g/dl), ser...

Introduction: Radioiodine (131-I) treatment for benign thyroid disease has a 70 year history. Among the radioactive isotopes, (131-I) can be used successfully. The intention of radioiodine treatment is primarily to induce a euthyroid or hypothyroid state, but in the case of large multinodular goitres, shrinkage represents a secondary aim of therapy. The optimal method for determining iodine-131 treatment doses for Toxic Thyroid nodule is unknown, and techniques have varied fro...

A 65-year-old Caucasian gentleman was admitted with weight loss and generally feeling unwell. X ray chest done a week before admission as part of routine investigation by the General Practitioner, showed healing rib fractures with diffuse sclerosis. Malignancy was initially suspected due to the bony changes in the chest X-ray. Hence a full body CT scan was done and was normal. Incidentally he was noted to have low adjusted calcium of 2.16 mmol/l (2.20–2.60), raised parath...

Case history: 73-year-old male was seen in breast clinic for right breast lump which was noted 6 weeks back with no nipple discharge. Mammogram and ultrasound confirmed bilateral gynaecomastia more on right side. Referred to endocrine clinic with abnormal hormone profile. He is a retired builder. He was a heavy smoker for 50 years and has stopped smoking 1 year back. He drinks socially and has never used illicit drugs. His only past medical history was GORD for which he takes ...

A 64 year old lady was admitted with a 2 day history of feeling generally unwell. Her relatives also reported new onset confusion over these 2 days. Her bloods showed raised inflammatory markers (CRP 110.3 mg/l, WCC 18.2×109/l) hypoalbuminemia (17 g/l), bilirubinemia (55 μmol/l) and a raised alkaline phosphatase (917 IU/l). She had recently been diagnosed with carcinoid syndrome; primary tumour situated in the terminal ileum with liver metastasis and had b...

Pituitary abscess is very rare accounting for 0.2 – 0.6% of all pituitary lesions. Only around 210 case reports have been described so far. We report a case of pituitary abscess presented as pituitary mass lesion with hypopituitarism.A 51 year old man was admitted with headache and found to have severe hyponatraemia. Past medical history included paranoid schizophrenia. Clinical examination was normal.Relevant investigations: ...

AKI is a potentially a life threatening condition and it is extremely crucial to investigate the root cause it order to manage the patient appropriately.Case reportA 30 years old female presented with complaints of generalized muscle weakness, lethargy and mood changes. She was found to have raised creatinine with significant drop in her GFR to 41. Rest of her electrolytes and full blood count were within normal range. She was comm...