Endocrine Abstracts

Introduction: Severe hypercalcemia is an uncommon but potentially life-threatening condition. Calcium plays a variety of roles and explains the impact of hypercalcemia on the functioning of different organs. We report the case of a patient with severe hypercalcemia revealed by a confusional syndrome.Observation: A 60 year old male patient, with a medical history of hypertension under treatment, presented a confusional syndrome of progressive onset which ...

Introduction: LADA (Latent Autoimmune Diabetes in Adults), is defined by the association of diabetes after 30 years, the presence of antibodies against pancreatic beta cells and the non-use of insulin therapy within 6 months of diagnosis. Graves’ disease is the first cause of hyperthyroidism associating thyrotoxicosis, goiterand exophthalmos with a prevalence 5 times higher in women.Case report: 37-year-old female patient with no notable history, la...

Introduction: Liraglutide is a glucagon-like peptide 1 (GLP-1) receptor agonist, approved for the treatment of adult patients with type 2 diabetes mellitus of a particular interest in the significant improvement of glycaemic, systolic blood pressure and lipid control with their impact on weight, making it possible to avoid this infernal spiral of weight gain-increased insulin resistance.Observation: 55-year-old female patient, known diabetic for 10 years...

Introduction: Parathyroid adenoma can be localized in an ectopic situation, especially at the mediastinal level. The localization at the level of the RLN chain lymph node has not been reported yet.Case presentation: A 67-year-old woman without clinical signs of hyperparathyroidism, having undergone a left isthmolobectomy for a thyroid nodule suspected of being malignant, with intraoperative discovery of lymphadenopathy of the left RLN chain lymph node. T...

Introduction: Amiodarone is a highly effective drug, used for the treatment of arrhythmias. However, it can cause either hypothyroidism or thyrotoxicosis. It leads to alterations in thyroid gland function or thyroid hormone metabolism, due to its high iodine content. Amiodarone-induced hypothyroidism is common in countries with high iodine dietary intake, and Amiodarone-induced thyrotoxicosis is more prevalent in regions with low iodine dietary intake. A large amount of iodide...

Introduction: Finding the optimal levothyroxine (LT4) dose regime to ameliorate the abnormally low levels of natural thyroid hormones, especially for thyroidectomized patients, is still challenging. Many researchers have studied various LT4 dosage regimen clinically; and ultimately, they proposed multiple variables affecting LT4 requirements including age, gender, body weight, body mass index (BMI), and body surface area (BSA). However, prescribing the most appropriate LT4 dos...

An endocrine specialist pharmacist has been running an adrenal incidentaloma clinic since September 2020. As of Jun-22 258 patients have been seen in clinic and managed using a local protocol. Adrenal incidentaloma patient referrals are screened as per current guidelines on receipt; those measuring <1 cm are declined, suspected adrenocortical carcinomas are seen by a consultant and referred elsewhere if needed. All others are seen by the endocrine pharmacist within 4 weeks...

Gums inflammation (gingivitis) if not treated on time and permitted to grow, ends into periodontitis in which alveolar bone that supports teeth is invaded and destroyed. Juvenile periodontitis is a genetic disorder and can occur without plaque and calculus. It is a disease of people below 30 years of age.Subjects and methods: This cross sectional study involved a total of 160 subjects including 80 chronic periodontitis patients and 80 healthy controls be...

We aimed to evaluate the risk factors for the development of definitive thyroid failure, to analyze the natural course of subclinical hypothyroidism and to quantify the incidence rate of overt hypothyroidism in elderly patients.Two hundred and fourteen patients (186 women and 28 men) over age 60 years with subclinical hypothyroidism and no previous history of thyroid disease were prospectively studied. Subjects were followed up for 6–72 months (mean...

Introduction: Primary hyperparathyroidism (PHPT) is a common endocrinopathy caused by inappropriate PTH secretion by the parathyroid glands, which leads to alterations in phosphocalcic metabolism. The aim of our study is to determine the prevalence of complications of PHPT.Materials and Methods: Retrospective descriptive study of 83 patients with primary hyperparathyroidism collected over a period of 07 years (between 2015 and 2022) in the endocrinology ...