Endocrine Abstracts

Introduction: Non-alcoholic fatty liver disease (NAFLD) represents the most common and fastest growing liver disease. Its incidence is associated with the global obesity epidemic.Objective: To develop a simple score to predict the risk of NAFLD in the obese patient.Methods and Materials: This is a descriptive cross-sectional study including 95 patients who consulted at the Human Obesity Research Unit of the National Institute of Nu...

Background: Pituitary apoplexy is a rare clinical syndrome due to abrupt hemorrhaging and/or infarction of the pituitary gland, generally within a pituitary adenoma. The outcome of acute apoplexy is variable and difficult to predict. This explains why the optimal management of acute pituitary apoplexy remains controversial. The aim of our study was to investigate the clinical, hormonal and radiological characteristics of pituitary apoplexy and to determine treatment outcomes.<...

Insulinoma is a very rare type of islet cell tumor. The aim of our study is to report our clinical experience with insulinoma in order to determine clinical, biological, radiological and therapeutic particularities of this tumor type.It’s a retrospective study, including five patients (three women and two men) referred to our department between 2005 and 2011 for hypoglycemia exploration. Mean age of our group is 39.8±15.4 years (ranges: 20&#150...

Introduction: Cushing disease (CD) is a condition due to an ACTH-secreting pituitary adenoma that is usually a microadenoma. Seldom, the lesion may be atypical by his size or his radiological aspect.The aim of this study is to analyze the clinical and biological data of CD with atypical radiological aspect (macroadenoma or other), to compare them to those of CD with a typical radiological aspect (microadenoma) and to determine the clinical or biological ...

Background: Resistin is a recently discovered adipocyte-secreted hormone that links obesity with insulin resistance and/or metabolic and cardiovascular risk. This study was designed to investigate whether serum resistin concentrations constitute a significant coronary risk factor, with a particular focus on diabetes and one of its microvascular complications; nephropathy.Methodology: Serum resistin was measured in 86 overweight patients with acute corona...

Introduction: Anaplastic thyroid cancers are undifferentiated malignancies accounting for 2% of thyroid cancers.Objective: To study the clinical, evolutionary and therapeutic characteristics of these carcinomas.Materials and methods: A retrospective study covering 7 cases collected at our ENT department between 1994 and 2021.Results: They were 6 women and one man with an average age of 50 (41-78). The reason ...

Introduction: Secondary hyperparathyroidism is the main disorder of mineral and bone metabolism associated with chronic kidney disease. This disorder is characterized by hypersecretion of parathyroid hormone (PTH). Given the high cost and unavailability of calcimimetics, surgery remains a good alternative. In the immediate postoperative period after parathyroidectomy, hypocalcemia is common and close monitoring is critical.Objective: The aim of our work ...

Introduction: Hyperparathyroidism is the clinical and biological manifestation of excessive and inappropriate parathyroid hormone (PTH) production. It is the third most common endocrinopathy. It is often secondary to a single adenoma (80%). Occasionally, it may be a multi-glandular disease (15-18%). Treatment is surgical.Objective: the aim is to evaluate therapeutic results after surgery for primary hyperparathyroidism.Method: This...

Introduction: Hyperparathyroidism is the third most common endocrinopathy. Minimally invasive surgery using a unilateral approach is now increasingly common. In such cases, preoperative localization of the lesion by imaging is essential. Among the techniques available, ultrasound and scintigraphy play a predominant role.Objective: our aim is to evaluate the diagnostic contribution of ultrasound and parathyroid scintigraphy in localizing the pathological ...

Introduction: hyperparathyroidism is an endocrinopathy affecting calcium metabolism. Its curative treatment is surgical. Postoperative hypocalcemia is one of the main risks of this surgery.Objective: The aim of this study is to identify predictive factors of postoperative hypocalcemia after surgery for primary hyperparathyroidism.Method: This is a retrospective study including 84 patients operated on for pimary hyperparathyroidism ...