Endocrine Abstracts

Background: As adoption of continuous glucose monitoring (CGM) continues to expand, lot more studies are investigating the effects of CGM on HbA1C and hypoglycaemia risks in people with Diabetes Mellitus (PwD). In PwD, established benefits of usage of CGM along with digital diabetes self-management and education (DSME) program in Indian real-world context are scarce. OneCare compares patients engaged in its “IMPACT’ DSME program alone vs program assisted by CGM.<...

Background: People with Diabetes (PwD) experience many obstacles in diabetes management including, but not limited to lack of motivation, limited knowledge on diabetes self-management and treatment adherence issues. Diabetes mandates regular follow-ups for good glycemic control and manage complications. Internet and smartphones, have revolutionized digital health and hence by employing digital health and technology, better outcomes may be achieved; which is realizable in India...

Background: Numerous studies have reported the role of the N-terminal of pro-opiomelanocortin (N-POMC1-76) and its smaller fragments; 1-28 and 1-49, in adrenal steroidogenesis and mitogenesis. A full understanding of this area will help to understand the pathophysiology of certain adrenal tumours but exactly how these peptides elicit this effect is unclear. We have recently identified an orphan G protein-coupled receptor (GPCR) as a possible N-POMC receptor. Preliminary data s...

Introduction: Nonmedullary carcinoma of thyroid is most common of thyroid carcinoma with familial predisposition and very low incidence.We describe cases of three brothers with familial nonmedullary thyroid carcinoma diagnosed over a span of six years clinical follow up.Case: 58 years male with swelling in neck for 5 days. On examination he had left thyroid nodule. Ultrasound thyroid showed multinodular goiter while fine needle aspiration cytology (FNAC)...

Background and aims: Rickets is a childhood condition resulting from impaired mineralisation of the growth plate, resulting in bony deformities. A retrospective survey was undertaken to identify causes of rickets in children treated at the Royal Manchester Children’s Hospital from 2009 to 2014.Methods: Cases of rickets were identified through a search of all paediatric radiology reports containing the words ‘Rickets’ or ‘Osteomalacia&...

Introduction: Diagnosis of sub acute thyroiditis is readily considered in a patient presenting with classical history and characteristic clinical features. Confirmation of diagnosis is based on particular set of laboratory investigations and supported by characteristic imaging findingsof Tc-99 scan. However, prescence of sub acute thyroiditis with normal thyroid scintigraphy findings is exceedingly rare.Case report: 51 years old postmenopausal female wit...

Retinoid-X-receptor (RXR) and retinoic acid receptor (RAR) are transcription factors; each expresses in α, β and γ isoforms. Whereas RAR plays roles in growth and differentiation, RXR regulates lipids homeostasis. Specifically, RXRβ mediates intracellular control of cholesterol levels. RXR is activated by 9-cis-retinoic acid (9-cis-RA), cervonic acid, docosapentaenoic acid, adrenic acid and arachidonic acid. The present investigation was aimed...

Introduction: Small-group teaching (SGT) has been widely adopted in medical education to promote problem-based learning and enhance the process of deep learning. Simulation via Instant Messaging - Birmingham Advance (SIMBA) is a simulation-based learning approach using WhatsApp and Zoom to increase participants’ confidence in managing various clinical scenarios.Aim: To investigate whether SIMBA provided similar knowledge and experiences as compared ...

Introduction: Simulation via Instant Messaging – Birmingham Advance (SIMBA) for Students is an online education model used to teach endocrine topics to pre-clinical medical and pharmacy students using simulated clinical cases delivered through WhatsApp and Zoom. In this study, we investigated the efficacy and acceptability of SIMBA for students compared to traditional small-group teaching (SGT).Methods: These SIMBA sessions were conducted from 2020 ...

Introduction: Simulation via Instant Messaging – Birmingham Advance (SIMBA) for Students is an online education model used to teach endocrine topics to pre-clinical medical and pharmacy students using simulated clinical cases delivered over WhatsApp. This study investigated the efficacy and acceptability of SIMBA for students compared with traditional small group teaching (SGT).Methods: The SIMBA sessions focussed on curriculum learning objectives a...