Endocrine Abstracts

Introduction: Renal cell carcinoma (RCC) is the most common type of malignant renal tumors in adults. It is often difficult to detect it precociously since early-stage renal tumors are usually asymptomatic and non-palpable. We report a case of RCC revealed by acute adrenal insufficiency (AAI).Case report: Mr. A.B, 46 years old, 30 pack-year smoker, with a medical history of gout treated with Allopurinol, was admitted to our department for acute adrenal i...

Introduction: The COVID-19 pandemic had a significant emotional and psychological impact on populations worldwide, especially vulnerable people with chronic diseases such as diabetics. The objective of our study was to assess the quality of life and psychological distress of diabetic patients and to study patients’ attitudes towards managing their diabetes.Methods: We conducted a cross sectional descriptive study involving 60 diabetic patients follo...

Introduction: Adrenal adenomas development has been partially explained by aberrant adrenal expression of some hormone receptors. Klinefelter’s syndrome is a common cause of hypergonadotropic hypogonadism, which is characterized by increased serum LH level. In this case, we report a patient with Klinefelter syndrome, who was later diagnosed with a non secreting adrenal adenoma.Case presentation: We report the case of a 57 years old patient, diagnose...

Introduction: Gelastic seizures have been typically described with hypothalamic hamartomas and precocious puberty. Invasive EEG recordings have shown that gelastic seizures originated from the hypothalamic hamartomas, however recent findings have shown that they might also arise from other central lesions, like tumors, malformations of cortical development, postinfectious foci and other hypotalamic or pituitary abnormalities. In this case, we describe a patient with gelastic s...

Introduction: Pituitary stalk interruption syndrome is a rare disorder characterized by a specific tirade: an absent or hypoplastic anterior pituitary gland, thin or absent infundibulum, and ectopic posterior pituitary location. This syndrome has been described in association with other somatic abnormalities and recently a polygenic etiology has been suggested. Herein, we report a case of type 1 diabetic patient, explored for short stature, revealing a pituitary stalk interrup...

Introduction: Growth hormone deficiency (GHD) is a rare cause of delay of growth. However, it is primordial to screen for it since its presence leads to a specific treatment which improves statural prognosis. GHD should be confirmed through stimulation tests such as Insulin Tolerance test (ITT) or Clonidine Stimulation Test (CST). The objective of our study was to compare these two diagnostic tools.Methods: We conducted a retrospective study in the endoc...

Introduction: The glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency in humans. In red blood cells, the pentose phosphate pathway is the only source of nicotinamide adenine dinucleotide (NADPH), and defense mechanisms against oxidative damage are highly dependent on G6PD activity. The occurrence of acute haemolysis in patient with G6PD deficiency and diabetes has been reported and ascribed to various mechanisms. Her we report a case of pat...

Introduction: Childhood obesity rates have globally increased in the last five decade. It is well known that eating habits are a crucial contributing factor. Our study aimed to understand the impact of dietary habits on this global issue.Methods: It was a comparative study including 50 obese children (G1) and 35 normal-weight children (G2) aged between 6 and 13 years old. Our study was conducted in the outpatient department of Bechir-Hamza Children’...

Introduction: Childhood obesity is a major global health problem that has reached alarming levels. We conducted our study to determine the influence of environmental factors on this international scourge. Methods: It was a comparative study involving 50 obese children (G1) and 35 normal-weight children (G2) aged between 6 and 13 years old. Our study was conducted in the outpatient department of Bechir-Hamza Children’s Hospital of Tunis, Tunisia from...

Introduction: Childhood obesity is influenced by various factors. Maternal health plays a crucial role in this public concern. We carried out our study aiming to uncover key insights into this relationship. Methods: It was comparative study in the outpatient department of Bechir-Hamza Children’s Hospital of Tunis, Tunisia, from December 26, 2022 to February 1, 2023. The study included 50 obese children (G1) and 35 normal-weight children (G2) aged be...