Searchable abstracts of presentations at key conferences in endocrinology

ea0063p454 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

Selective arterial calcium stimulation test in two cases with occult insulinoma

Ahmadova Konul , Tam Abbas Ali , Topaloglu Oya , Akkan Koray , Bostancı Birol , Ersoy Reyhan , Cakir Bekir

Introduction: 80–90% of insulinomas are smaller than 2 cm, equally located in the head, body and tail of pancreas. Computer tomography (CT) is 75%, magnetic resonance imaging (MRI) is 55–90%, endoscopic ultrasonography (EUS) is 85–95% and selective arterial calcium stimulation test (SACST) is 95–100% sensitive in the diagnosis of insulinomas. Here, we presented two cases of insulinoma which could not be located by conventional methods and evaluated with SAC...

ea0070aep321 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Severe insulin resistance with cirrhosis: A case report

Durmaz Himmet , Evranos Ogmen Berna , Ahmadova Konul , Kucukcongar Yavas Aynur , Keskin Caglar , Dirikoc Ahmet , Cakir Bekir

Background: Alstrom syndrome is a rare autosomal recessive genetic disorder characterised by vision loss, hearing loss, childhood obesity, insulin resistance and hyperinsulinemia, type 2 diabetes, hypertriglyceridemia, cardiomyopathy, and progressive pulmonary, hepatic, and renal dysfunction. Hyperinsulinemia develops early, and pancreatic islets show beta-cell proliferation, thus suggesting that both insulin resistance and increased insulin secretion might contribute to gluco...

ea0070ep100 | Bone and Calcium | ECE2020

Nonmedullary hypercalcitoninemia in a hypocalcemic patient: Shoud we look at serum calcitonin level in the differantial diagnosis of hypocalcemia?

Durmaz Himmet , Aydin Cevdet , Ahmadova Konul , Dirikoc Ahmet , Ersoy Reyhan , Cakir Bekir

Background: Although high levels of calcitonin suggest neoplastic proliferations such as medullary thyroid carcinoma, C cell hyperplasia and some neuroendocrine tumors, systemic diseases and drugs may also elevate calcitonin. Although calcitonin is not as effective as PTH, it has got a role in calcium hemoastasis. Supraphysiological calcitonin level can lead to hypocalcemia.Case presentation: A 57-year-old male patient was diagnosed with epilepsy with co...

ea0073aep884 | Late Breaking | ECE2021

A tru-cut biopsy proven rare thyroid neoplasia in a giant nodule with a benign fine needle aspiration cytology

Leyla Akdoğan , Ahmadova Konul , Bestepe Nagihan , Burcak Polat Sefika , Dilek Imdat , Aydin Cevdet , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

IntroductionExtramedullary plasmacytoma (EMP) is a plasma cell neoplasm of extraosseous tissues. Less than 5% of all plasma cell neoplasms develop extramedullary. EMP is most common in the upper respiratory tract and oral cavity. The thyroid gland is one of the extremely rare regions. It is more common in men and the average age at diagnosis is 55. Primary thyroid plasmacytoma is one of the rare thyroid neoplasms. It often manifests as a rapidly growing ...

ea0073ep239 | Late Breaking | ECE2021

A rare cause of levothyroxine malabsorption: İleostomy

Leyla Akdoğan , Ahmadova Konul , Sacikara Muhammed , Ali Tam Abbas , Ozdemir Didem , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

IntroductionIt is recommended to determine levothyroxine (LT4) dose individually in patients with hypothyroidism. However, higher doses of LT4 therapy are required to achieve target TSH levels in significant number of patients. Oral LT4 absorption occurs in the small intestine, especially in the jejunum and proximal ileum, while a small amount is absorbed in duodenum. Causes of LT4 malabsorption include helicobacter pylori infection, chronic atrophic gas...

ea0073aep782 | Late Breaking | ECE2021

Heterozygous 461A> T (p.Asp154Val) Mutation in POR gene in a male case

Müge Keskin , Ahmadova Konul , Nurcanİnce , Narin Nasirogluİmga , Cevdet Ceylan Ahmet , Aydin Cevdet , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

BackgroundCytochrome P450 oxidoreductase (POR) deficiency is an autosomal recessive steroidogenesis disorder similar to combined deficiencies of 17a-hydroxylase, 17, 20-lyase, 21-hydroxylase. POR deficiency (PORD) is a very rare type of congenital adrenal hyperplasia(CAH) characterized by sexual development disorders and skeletal anomalies. We present a case that was evaluated with a prediagnosis of nonclassical CAH and was found to have a heterozygo...