Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep12 | Adrenal cortex (to include Cushing's) | ECE2017

Evaluation of cardiovascular risk in patients with adrenal incidentaloma

Yorulmaz Goknur , Akalin Aysen , Yagiz Burcu

Introduction: Recent studies indicate that patients diagnosed with adrenal incidentaloma may present with cardiovascular disease. The aim of this study was to investigate markers of subclinical cardiovascular disease in patients with adrenal incidentaloma and healthy control group.Methods: This study included 50 patients with non-functional adrenal adenoma and 30 healthy controls. BMI and waist circumference of the patients were measured. The lipid param...

ea0049ep1033 | Pituitary - Clinical | ECE2017

A rapidly resolving prolactinoma with cabergoline treatment

Yorulmaz Goknur , Akalin Aysen , Akcan Esra

Introduction: Prolactinomas are the most common pituitary tumors. Macroadenomas are rarely seen. Dopamine agonists such bromocriptin and cabergoline are the preferred treatments for prolactinomas. Herein, we report a patient with macroadenoma whose adenoma has resolved rapidly with cabergoline treatment.Case: A 49 year old male patient evaluated for weakness and headache. After detection of central hypothyroidism he was referred to our department. His pr...

ea0041ep357 | Clinical case reports - Thyroid/Others | ECE2016

Postpartum osteoporosis associated with hypercalcemia and hypoparathyroidism

Kebapci Nur , Yorulmaz Goknur , Akalin Aysen

A lactating 31-year-old woman who developed L5 vertebral compression fracture 2 months after the delivery of her first child is presented. Serum concentrations of Ca was 10.24 mg/dl (8.6–10.2 mg/dl), phosphorus was 4.1 mg/dl (2.7–4.5 mg/dl), albumin was 4.6 mg/dl, ALP was 210 U/l (35–105 U/l), PTH was 13.8 pg/ml (15–65). There was axial osteoporosis, as assessed by dual-energy X-ray absorptiometry. Z score; L1 (−3), L2 (−3.8), L3 (&#872...

ea0020p275 | Clinical case reports and clinical reports | ECE2009

Paget’s disease of sacrum: a case report

Yorulmaz Goknur , Akalin Aysen , Serbetci Banu Sensoy

Background: Paget’s disease may affect as many as 3% of adults older than 40 years of age; it is often asymptomatic and usually progresses slowly. Paget’s disease affects men and women almost equally, but men tend to be more symptomatic. The disease is usually not clinically apparent until age 50–60 years. It usually progresses slowly and does not develop in new sites. Many different bones can be affected, and the lesions can vary from single, monostotic lesions...

ea0049ep244 | Bone & Osteoporosis | ECE2017

Neutrophil lymphocyte ratio in 6 month teriparatide therapy of osteoporosis

Taskiran Bengur , Yorulmaz Goknur , Cansu Guven Baris , Akalin Aysen

Aim: Low BMD and atherosclerosis may share similar underlying biological mechanisms including higher serum phosphate and inflammation. Neutrophil-lymphocyte ratio (NLR) as a simple marker of inflammation. There are scarce data indicating improved atherosclerosis and cardiovascular events with biphosphonate and teriparatide therapy. We aimed to evaluate NLR before and after 6 months of teriparatide therapy in patients with severe established osteoporosis....

ea0022p109 | Bone/Calcium | ECE2010

Primary hyperparathyroidism at pregnancy

Yorulmaz Goknur , Kebapci Nur , Onbasi Kevser , Efe Belgin , Akalin Aysen

Primary hyperparathyroidism during pregnancy is a rare condition associated with a high frequency of complications in both mother and fetus. Operation in the second trimester is offered. Here we report about a case with hyperemesis and hyperparathyroidism during routine laboratory examinations.A 30-years-old pregnant woman attendant our policlinic with hyperemsis gravidarum. Her calcium and parathormone level were elevated; 11.6 mg/dl and 135 pg/ml, resp...

ea0020p303 | Clinical case reports and clinical reports | ECE2009

Large intrathoracic goiter mimicking lung cancer

Onbasi Kevser , Akalin Aysen , Yorulmaz Goknur , Kebapci Nur , Efe Belgin

Herein, we present a case of a 68-year-old woman who had hyperthyroidism and a large mass lesion in the upper portion of her right lung. The patient had a history of previous subtotal thyroidectomy 40 years before. A few years after the operation she noticed some enlargement on her neck. Two years before the admission she was evaluated for some unrelated complaint and a large mass was discovered on her right lung on X-ray examination and she was considered to have a lung cance...

ea0014oc12.6 | Diabetes | ECE2007

Short-term effects of atorvastatin on endothelial functions and oxidized LDL levels in type 2 diabetic patients

Akalin Aysen , Temiz Gokhan , Akcar Nevbahar , Sensoy Banu

Objective: We aimed to investigate the short term effects of atorvastatin on endothelial function and oxidized LDL (oxLDL) levels and to evaluate the association of endothelial dysfunction to oxLDL levels and inflammatory markers in type 2 diabetic patients.Material and methods: After ethical committee approval thirty type 2 diabetic and 11 healthy subjects with LDL levels between 100–160 mg/dl. Without a history of cardiovascular event were include...

ea0081ep722 | Pituitary and Neuroendocrinology | ECE2022

Assessment of the thyroid status in acromegaly patients

Yuksel Bahar Gokce Sezgin , Yorulmaz Goknur , Kalkan Ahmet Toygar , Kebapci Medine Nur , Akalin Aysen , Efe Belgin

Acromegaly is a rare disease associated with hypersecretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland, with elevated morbidity and mortality. Acromegaly and thyroid diseases show high co-occurrence. In our study; we aimed to determine the relationship between disease activity at the time of admission and after treatment with the presence of goiter, presence of nodules, and possible accompanying thyroid malignancy in 119 patients with acromega...

ea0090p810 | Late-Breaking | ECE2023

Evaluation with Dynamic Contrast Enhancement (DCE)-MRI in Patients with Acromegaly

Toygar Kalkan Ahmet , Ozer Ozge , Toprak Ugur , Efe Belgin , Akalin Aysen , Nur Kebapci Medine , Yorulmaz Goknur

Acromegaly is a rare disease with high morbidity and mortality associated with excessive secretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland. In patients with acromegaly, residue may remain after surgical treatment, and disease control is attempted with surgery, medical treatment or radiotherapy for these patients. Pituitary imaging, IGF-1 and GH measurement are used in the follow-ups. Dynamic Contrast Enhancement perfusion MRI provides infor...