Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep763 | Clinical case reports - Thyroid/Others | ECE2017

Endocrine complications in a female patient with β-thalassemia major following bone marrow transplantation

Cima Luminita Nicoleta , Lambrescu Ioana Maria , Stejereanu Lavinia , Colita Anca , Fica Simona

We report the case of a 14-year-old female patient with β-thalassemia major (β-TM) that presented numerous endocrine complications following bone marrow transplantion (BMT). The patient was admitted in our department for endocrine evaluation 3 years after BMT. She was diagnosed with β-TM at 1 year of age and received chronic blood transfusions and oral chelating therapy until 2012 when BMT was performed. The patient developed acute skin and intestine graft-versu...

ea0041ep365 | Clinical case reports - Thyroid/Others | ECE2016

Graves’ orbitopathy and Graves’ disease after bone marrow transplant in a patient with Fanconi anemia

Cima Luminita Nicoleta , Stejereanu Lavinia , Lambrescu Ioana Maria , Colita Anca , Barbu Carmen Gabriela , Fica Simona

Introduction: Endocrinopathies are a common late effect of haematopietic stem cell transplantation, resulting in thyroid dysfunction, impaired growth and pubertal development during childhood and metabolic syndrome. Because of the possible endocrine complications, transplanted patients need life-long endocrine follow-up.Case report: A 14-year-old male patient with a history of Fanconi anemia (7 years), bone marrow transplant (10 years) and Graves Disease...

ea0090p490 | Thyroid | ECE2023

Challenges in the management of endocrine complications after hematopoietic stem cell transplantation – could it be reconstitution Graves’ disease?

Grosu Iustina , Dumitrache Sabina-Maria , Stan Raluca , Zubaci Ana , Iliescu Marina , Tarna Mihaela , Jercan Cristina , Colita Anca , Nicoleta Cima Luminita , Fica Simona

Background: The rapid advancements in the field of allogenic hematopoietic stem cell transplantation (allo-HSCT) and better management of acute postprocedural complications have led to increased life expectancy, but at the same time to higher incidences of long-term complications. Conditioning regimens (chemotherapy, total body irradiation), immunosuppresive treatments and immune dysregulation threaten endocrine and metabolic functions, leading to late effects, including hypog...

ea0056gp188 | Pituitary / Growth Hormone ' IGF Axis | ECE2018

Growth disorders in paediatric survivors of hematopoietic stem cell transplantation after chemotherapy-only conditioning- the experience of a single center

Cima Luminita-Nicoleta , Lambrescu Ioana Maria , Nedelea Lavinia , Sava Elisabeta , Leca Bianca , Vadana Elena-Alexandra , Colita Anca , Barbu Carmen Gabriela , Fica Simona

Objective: The reported incidence of growth disorders in hematopoietic stem cell transplantation (HSCT) recipients ranges from 20 to 80% and it was usually described in patients that were given total body irradiation (TBI) in the conditioning regimen. Because the effect of chemotherapy-only conditioning is less clear, we investigated the frequency of growth failure in our series of children treated with HSCT for different disorders without TBI as part of the conditioning proto...