Endocrine Abstracts

Aims: To examine, in children with Osteogenesis Imperfecta (OI): the prevalence of overweight and obesity, longitudinal trends in body mass index (BMI) z-scores and total body fat percentage (TBF) assessed on dual-energy X-ray absorptiometry (DXA) scans, correlation between BMI and TBF and fractures and BMI z-score.Methods: Retrospective cross-sectional and longitudinal analysis of children with OI, with minimum 5 years data on DXA scans, at a single nat...

Background: The National Paediatric Diabetes audit (NPDA) reports increasing number of children and young people with type 2 diabetes (CYP2D). CYP2D are less likely to receive all recommended health checks compared to those with type 1 diabetes (33% vs 59% respectively) and do not receive treatment for complications even when they are identified (T2D spotlight audit 2019/20). We assessed variation in care across different units against the national T2D guideli...

Introduction: Diabetes-related Ketoacidosis (DKA) is a commonly-encountered acute endocrine emergency requiring prompt recognition and treatment. DKA is triggered by risk factors that are often preventable. There are limited studies evaluating the precipitating causes of DKA and depicting their trends over the years. The latter is important in the prevention of DKA by ensuring appropriate education and interventions.Aim: To study the trends of aetiologie...

Introduction: Diabetes related ketoacidosis (DKA) is usually associated with type 1 diabetes mellitus (T1DM). However, DKA is increasingly being recognised in type 2 diabetes mellitus (T2DM). We studied the differences in prevalence and precipitating factors of DKA between T1DM and T2DM.Methods: This retrospective study included all DKA episodes from January to November 2021 in six hospitals in the West Midlands, UK. DKA was diagnosed as serum glucose&#8...

Background: Hyperosmolar hyperglycaemic state (HHS) is an acute metabolic complication of diabetes that can lead to significant morbidity and mortality if managed incorrectly. With <1% prevalence, there is limited published literature available on HHS and most management guidelines worldwide are based solely on expert advice and opinions.Aims: To study the precipitating causes and identify baseline practises of HHS management, to highlight areas for ...