Searchable abstracts of presentations at key conferences in endocrinology

ea0014p460 | (1) | ECE2007

Selected parameters of lipid metabolism in patients with Turner’s syndrome

Wikiera Beata , Barg Ewa , Noczynska Anna

Women with Turner syndrome (TS) more frequently develop cardiovascular disease. Abnormal lipid metabolism is a well known risk factor for ischemic heart disease. Adiponectin as well as cytokines are useful tool in evaluation the fat tissue metabolism.The aim of the study was to evaluate the relationship between adiponectin, TNF-alpha, IL-6 and lipids in patients with TS.Patients and method: The study group consisted of 87 girls wit...

ea0022p496 | Female reproduction | ECE2010

The impact of the disease on life quality and health concept in young women with Turner’s syndrome

Wikiera Beata , Szpich Elzbieta , Barg Ewa , Noczynska Anna

The individual development of patients with Turner’s syndrome (TS) is determined by the illness from the moment of diagnosis. The aim of the study was to determine life quality (QL) of TS patients and their concept of health.Patients and methods: Twenty-six TS patients aged 18–25 who experienced many years of treatment. R L Schaloc, K D Keith Life Quality Questionnaire was used to determine their QL. Their views on health were analyzed on the b...

ea0014p510 | (1) | ECE2007

The assesment of life quality satisfaction in women with Turner’s syndrome

Wikiera Beata , Szpich Elzbieta , Barg Ewa , Noczynska Anna

Quality life satisfaction is important for personal resources analysis and perspectives for coping with ilness.The aim of the study was to present a psychological portrait of a woman with Turner’s syndrome (TS) and assessing perspectives for increased well-being of such patients. The study concerns psychological aspects of TS women’s own assessment of their health and illness.The area of interest was:<p class="...

ea0016p359 | Growth and development | ECE2008

Lipid peroxidation as possible mechanism of apoptosis activation in low birth weight children

Barg Ewa , Gasiorowski Kazimierz , Wikiera Beata , Skoczynska Anna , Turczyn Barbara , Wojcik Elzbieta , Grabowski Marcin

Children born with low birth weight (LBW, below 2500 g) exhibit slower development with deficit of height susceptibility to recurrent infections, especially of respiratory tract and, in adulthood, an increased risk of developing syndrome X. One possible explanation could be an enhanced elimination of cells by apoptosis.The aim of this study was evaluate of mechanism of lipid peroxidation and activity of caspase 3 in children with low birth weight.<p ...

ea0014p251 | (1) | ECE2007

Obesity in pre-school children –new epidemic problem?

Barg Ewa , Joanna Chmielarska , Barbara Adamska , Inna Begar , Agnieszka Konieczna , Malgorzata Skarzynska

In the opinion of the World Health Organization the obesity will become one of four major epidemics of the 21st century. The most important factor for its occurrence is the lifestyle.The aim of the research was to analyse the body mass index (BMI) of pre-school children and their parents and the components of their lifestyle, such as diet, sports and free time activities.Material and Methods: The two-stage study included 537 childr...

ea0014p267 | (1) | ECE2007

The polymorphism of PPAR and susceptibility to atherosclerosis in children with low birth weight (below 2500 g)

Barg Ewa , Skoczynska Anna , Wikiera Beata , Chacka Dorota , Glab Ewa , Lebioda Arleta , Turczyn Barbara

Children, who are born with low birth weight (less 2500 g) are known to have an increased risk of developing lipid disturbances and atherosclerosis in later live.PPAR alpha activity could play a regulatory role in the pathogenesis of hyperlipidemia and a modulatory role in the control of inflammatory response.The aim of this study was to determine whether the presence of polymorphism in gene of peroxisome proliferators-activated re...

ea0016p596 | Paediatric endocrinology | ECE2008

The superoxide dismutase and lipid peroxide in children with Down syndrome and congenital heart disease

Wojcik Elzbieta , Barg Ewa , Gromkowska Malgorzata , Maslowska Ewa , Wikiera Beata , Kalita Danuta , Gamian Elzbieta , Turczyn Barbara , Skoczynska Anna

Metabolic disturbances occur more often in patients with Down Syndrome (DS, trisomy 21) than in the health population.Superoxide dismutase (SOD-1), the main enzyme in the antioxidative system, is coded on chromosome 21. Disturbances in the antioxidative system may play a major role in the development of complications of CHD with arterio-venous shunt.The aim was to evaluate the activity of SOD-1 and concentration of LPO in children ...

ea0035p1057 | Thyroid (non-cancer) | ECE2014

Analysis of chosen polymorphisms in FoxP3 gene in children and adolescents with autoimmune thyroid diseases

Bossowski Artur , Borysewicz-Sanczyk Hanna , Wawrusiewicz-Kurylonek Natalia , Szalecki Mieczyslaw , Wikiera Beata , Barg Ewa , Mysliwiec Malgorzata , Kucharska Anna , Bossowska Anna , Gorska Maria , Kretowski Adam

Forkhead box P3 (Foxp3) is an important regulatory factor for the development and function of T regulatory cells (Tregs). Moreover it has been established that deficiency of the Foxp3 gene in Treg cells suppresses their regulatory function leading to the development of autoimmune thyroid diseases (AITDs). The aim of our study was to estimate the association of three polymorphism of FOXP3 gene with the predisposition to GD and HT in children.<p class="abst...