Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep159 | Calcium and Bone | ECE2022

Long term treatment with teriparatide in hypoparathyroidism

Spada Antonio , Bosco Daniela , Santonati Assunta

Hypoparathyroidism is, in Italy, an orphan disease because the hormonal replacement therapy is possible only with teriparatide (fragment 1–34 of of human parathyroid hormone). Otherwise the patients use oral calcium and calcitriol. This scheme of therapy obtained correct plasmatic calcium and phosphate levels, correct urinary excretion of calcium and phosphate, adequate quality of life – QoL only in a little percentage of patients. Especially kidney stones, intra-ren...

ea0084op-12-63 | Oral Session 12: Nodules and Diagnostic | ETA2022

Real-world performance of a novel dual-component molecular assay in cytologically indeterminate thyroid nodules: a single institutional experience

Sponziello Marialuisa , Grani Giorgio , Verrienti Antonella , Pecce Valeria , Del Gatto Valeria , Bosco Daniela , Ascoli Valeria , Filetti Sebastiano , Durante Cosimo

Objective: We developed a novel dual-component molecular assay as an ancillary method to improve clinical decision-making in patients with cytologically indeterminate thyroid nodules. The assay includes next-generation sequencing (NGS) based detection of mutations in 23 thyroid cancer related genes and digital polymerase chain reaction (dPCR) evaluation of the expression levels of a microRNA strongly associated with thyroid cancer. The method was designed as a “rule-out&#...

ea0063gp258 | Thyroid Nodules and Cancer 2 | ECE2019

Predictors of malignancy in thyroid FNA classified as high-risk indeterminate lesions (TIR3B): combining ultrasonographic and cytology features

Cozzolino Alessia , Pozza Carlotta , Faggiano Antongiulio , Pofi Riccardo , Ascoli Valeria , Di Gioia Cira , Bosco Daniela , Lenzi Andrea , Isidori Andrea M , Giannetta Elisa , Gianfrilli Daniele

Introduction: The new Italian cytological classification of thyroid nodules published in 2014 has replaced the TIR3 ‘indeterminate’ category into two subcategory with different risk of thyroid cancer (TC): TIR3A, low-risk indeterminate lesion and TIR3B, high-risk indeterminate lesion. The aim of our study was to describe the incidence of TIR3B in a large prospective cohort of patients, the risk of TC, and its correlation with anamnestic, ultrasonographic (US) and cyt...