Searchable abstracts of presentations at key conferences in endocrinology

ea0090p44 | Calcium and Bone | ECE2023

CYP24A1 mutation - a rare cause of hypercalcemia and nephrocalcinosis in adulthood

Brunerova Ludmila , Reeš Ondrej , Zoubkova Veronika , Votypka Pavel

Background: CYP24A1 gene encodes the enzyme vitamin D 24-hydroxylase, which converts active vitamin D to inactive metabolites. More than 20 currently described, usually biallelic pathogenic variants of this gene are responsible for idiopathic infantile hypercalcemia manifested typically in childhood (often in newborns) with hypercalcemia, hypercalciuria and nephrocalcinosis. However, a few patients (mostly with monoallelic heterozygous pathogenic variant) can develop mild symp...

ea0026p734 | Diabetes (epidemiology, pathophysiology) | ECE2011

Does anxiety influence food preference and insulin resistance in healthy men?

Brunerova Ludmila , Potockova Jana , Horacek Jiri , Andel Michal

Introduction: We tested our hypotheses that higher anxiety/depression scores can be connected with food preference of carbohydrates and higher insulin resistance.Methods: We examined 42 healthy men (average age 43.5±7.4 years, average BMI 27.4±5.7 kg/m2). Study protocol included filling in the self-asssessing scores of anxiety (SAS) resp. depression (SDS), carbohydrate-craving questionnaire (CCQ); assessment of 3-days diet records, h...

ea0022p633 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Relationship between metabolic parameters and central dopaminergic activity in healthy men

Brunerova Ludmila , Horacek Jiri , Potockova Jana , Andel Michal

Background: Dopaminergic agonists have been proved to improve control of diabetes and lipids. Central dopaminergic activity can be measured by apomorphin test (apomorphin increases GH and decreases prolactin levels, which is a marker of dopaminergic activity).The aim of our study was to evaluate the relationship between central dopaminergic activity and metabolic parameters in healthy men.Methods: We examined 42 healthy men (averag...

ea0014p520 | (1) | ECE2007

Food preference, central serotoninergic activity, depression and insulin resistance in obese and lean healthy men: a pilot study

Brunerova Ludmila , Potockova Jana , Horacek Jiri , Andel Michal

Objective: Higher anxiety/depression scores can be connected with food preference of carbohydrates, with increased insulin secretion and thus can lead to insulin resistance. Three hypotheses were postulated: 1. more depressive (still in the normal range) subjects do not differ in the central serotoninergic activity from those less depressive. 2. the former do not differ in food preference and 3. in insulin resistance from the latter.Methods: healthy men,...