Searchable abstracts of presentations at key conferences in endocrinology

ea0029p188 | Bone & Osteoporosis | ICEECE2012

Comparison of the effects of hormone replacement therapy on bone mineral density, lipid profiles, and biochemical markers of bone metabolism

Namkung J. , Chung Y. , Kwak S. , Kim J. , Kim M.

Objective: To assess the effects of hormone replacement therapy on bone mineral density (BMD), biochemical markers of bone turnover, and lipid profiles in postmenopausal women.Methods: We retrospectively reviewed the medical records of 199 postmenopausal women who had received care at the Department of Obstetrics and Gynecology of Catholic University Seoul St. Mary’s Hospital between January 1994 and December 2008. The patients were divided into the...

ea0026p661 | Diabetes therapy | ECE2011

Effect of amino acid residues on N-terminal extension of GLP-1/IgG-Fc fusion protein

Lee C , Boyineni J , Chung H-S , Jang S-H

Glucagon-like peptide-1 (GLP-1) is an incretin hormone playing an important role in glucose-dependent insulin secretion and β-cell growth. However, GLP-1 is rapidly degraded by dipeptidyl peptidase IV (DPP-IV) in vivo. Many attempts have been made to develop long-acting GLP-1 analogs with chemical modification, amino acid substitution, and fusion protein technology. We previously showed that the N-terminal Ala- or Gly-extended GLP-1 and human immunoglobulin ...

ea00100oc2 | Oral Communications | SFEEU2024

Non-islet cell tumour hypoglycaemia in adrenocortical carcinoma responding to combined growth hormone and corticosteroid therapy

Plowman C E , Soruna O , Pittaway J , Goodchild E , Shamash J , Chung TT , Abdel-Aziz T E , M Drake W

Case History: A 26-year-old woman with known metastatic adrenocortical carcinoma (ACC) was transferred to our department with recurrent severe hypoglycaemic episodes. Her ACC was diagnosed in 2018 and a 175 × 130 × 89 mm 1200 g mass was surgically resected (ENS@T stage-II, Weiss score-5, Ki-67 20%, Helsinki score-28). Her disease progressed despite adjuvant radiotherapy, mitotane and three chemotherapy regimens. In January 2023, she began experiencing episodes of pro...

ea0029p504 | Diabetes | ICEECE2012

Glycoalbumin is the best indicator for glycemic variability assessed by continuous glucose monitoring

Suh S. , Joung J. , Park S. , Cho Y. , Jin S. , Kim S. , Kim H. , Bae J. , Kim S. , Chung J. , Min Y. , Lee M. , Lee M. , Kim K. , Kim J.

Aims: We investigated the interrelationship between HbA1c, fructosamine, glycoalbumin (GA), 1,5-anhydroglucitol (1,5-AG) with glycemic variability data from continuous glucose monitoring system (CGMS).Methods: Seventy diabetic patients (mean age of 54 years including seven type 1 diabetes mellitus subjects) were enrolled, and all wore a CGMS for 72 hours. For the parameters of glucose excursion, mean glucose, standard deviation (SD) of glucose, the area ...

ea0029p685 | Diabetes | ICEECE2012

A Randomized controlled trial of the effect of internet based mentoring program for type 1 diabetes patients with inadequate glycemic control

Suh S. , Park S. , Cho Y. , Joung J. , Jin S. , Kim S. , Kim H. , Bae J. , Kim S. , Chung J. , Min Y. , Lee M. , Lee M. , Kim K. , Kim J.

Introduction: Widespread availability of internet makes it an attractive communication tool among patients and providers. However, the clinical benefit of telemedical support on diabetes care remains inconclusive. This study is to determine whether an internet based mentoring program can improve glycemic control in type 1 diabetes (T1DM) patients with inadequate glycemic control.Methods: Patients with T1DM on intensive insulin therapy and with HbA1c &#x2...

ea0029p1388 | Pituitary Clinical | ICEECE2012

Diabetes insipidus could be the initial sign of primary hypophysitis

Suh S. , Park S. , Joung J. , Cho Y. , Jin S. , Kim S. , Kim H. , Bae J. , Kim J. , Kim S. , Chung J. , Min Y. , Lee M. , Lee M. , Kim K.

Introduction: The natural history of primary hypophysitis is incompletely understood and best treatment remains controversial.Methods: We performed a retrospective study of 19 patients (mean age of 47 years, fifteen women and four men) who were diagnosed with primary hypophysitis in Samsung Medical Center in Seoul, Korea, from January 2001 to October 2011.Results: Two patients had recent pregnancy and underlying autoimmunity. Most ...