Searchable abstracts of presentations at key conferences in endocrinology

ea0073ep127 | Endocrine-Related Cancer | ECE2021

Advanced metastatic disease in a low-grade pulmonary neuroendocrine tumor: a case report with partial response to targeted therapy

Cristiana Calin , Dusceac Roxana , Burcea Iulia-Florentina , Catalina Poiana

BackgroundIt has been well recognized that grade heterogenity exists within well-differentiated neuroendocrine tumors (WD-NETs). Targeted therapy plays an important role in metastatic disease control.Case presentationWe present the case of a 58-year-old male patient who was diagnosed with a pulmonary tumor on computer tomography (CT) and underwent a posterobasal left lobectomy. On immunohistochemical staining...

ea0081p753 | Thyroid | ECE2022

Somatostatin analog therapy in advanced sporadic medullary thyroid carcinoma: a case report

Dumitriu Roxana , Cristiana Calin , Florentina Burcea Iulia , Dumitrascu Anda , Poiana Catalina

Introduction: Medullary thyroid carcinoma (MTC) is an aggressive neuroendocrine tumor derived from C cells that is responsible for approximately 5% of the gland malignancies, most of them occuring sporadically. Lymph node metastasis may occur early in disease pathogenesis and is one of the most important negative prognostic factor. Surgery is the only curative therapy while other chemotherapeutic options are limited. Neuroendocrine differentiated C cells may express somatostat...

ea0081ep968 | Thyroid | ECE2022

Thyrotoxicosis and multisystemic inflammatory syndrome in a patient with recent history of COVID-19

Cristiana Calin , Ioana Iulia Greere Daniela , Burcea Iulia Florentina , Poiana Catalina

Introduction: There is evidence on the association of subacute thyroiditis (SAT) and SARS-CoV-2 infection, the first case report being described in a young woman back in July 2020 (1). Multisystemic inflammatory syndrome in adults (MIS-A) is a rare complication of SARS-CoV-2, usually 2 to 12 weeks after initial infection. The development of Graves disease after SAT is rare, with approximately 31 reported cases, of which only 5 occurring in men (2). We pre...

ea0090p233 | Thyroid | ECE2023

Impact of SARS-COV-2 infection on the endocrine system: a case series

Cristiana Calin , Florentina Burcea Iulia , Dobre Ramona , Dumitriu Roxana , Trifanescu Raluca , Poiana Catalina

Introduction: There is evidence that SARS-COV-2 infection can result in development of endocrine disturbances. Expression of the angiotensin-converting enzyme 2, which is postulated to be at the center of the pathogenesis of COVID-19, has been reported in various endocrine tissues.Case Series: We retrospectively analyzed 12 patients with recent history of SARS-COV-2 infection: 5 cases with subacute thyroiditis (SAT), 2 cases with GravesÂ’ disease, 2 ...

ea0099ep152 | Endocrine-Related Cancer | ECE2024

Tumor behaviour in neuroendocrine tumors (NETs) of unknown primary versus known primary site location

Cristiana Calin , Dobre Ramona , Florentina Burcea Iulia , constantin teodor , Poiana Catalina

Introduction: While most of neuroendocrine tumors (NETs) primary sites are discovered, NETs of unknown primary are not entirely uncommon in the clinical setting. The primary site is a significant factor in terms of overall prognosis. The aim is to determine whether NETs of unknown primary site location (NET-USs) have more aggressive behavior than those with a known primary location. Matherials and Methods: We retrospectively studied 50 consecutive patien...